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Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents
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JoVE Journal Engineering
Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents

Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents

DOI:
10.3791/53607-v

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08:59 min

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April 15, 2016

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, , ,
1Imaging Physics,University of Texas M.D. Anderson Cancer Center, 2Advanced Imaging Research Center,University of Texas Southwestern Medical Center

Chapters

  • 00:05Title
  • 01:12Preparation of Hyperpolarized Pyruvate
  • 03:10Preparation of the Enzyme Phantom
  • 04:13Run Quality Assurance (QA) and Positioning Scans
  • 05:21Radial Echo Planar Spectral Imaging Scan Setup and Running Dissolution
  • 07:17Results: Radial Spectroscopic Imaging of Single Enzyme Phantom
  • 07:57Conclusion

Summary

Automatic Translation

Automatic Translation

A multi-compartment dynamic phantom is used to simulate some biology of interest for metabolic studies using hyperpolarized magnet resonance agents.

Tags

Multi-compartmentDynamic Single Enzyme PhantomHyperpolarized Magnetic Resonance AgentsConversionPyruvateLactateMagnetic Resonance ImagingControlled Phantom EnvironmentHyperpolarized MRI FieldChemical ConversionMetabolismIn VivoControllable And RepeatableCancer DiagnosisMetabolic ImagingCardiac MetabolismTime ConstraintsHyperpolarized MediaDissolutionEjection StepsGadoteridol SolutionPyruvic Acid Solution

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