Ed Lein

Cell Types Program, Allen Institute for Brain Science

Affiliated withAllen Institute for Brain Science

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 346	2018

Other Publications

Article	Year
Genome-wide atlas of gene expression in the adult mouse brain. Nature\| PubMed ID: 17151600	2007
Neuroinformatics for genome-wide 3D gene expression mapping in the mouse brain. IEEE/ACM transactions on computational biology and bioinformatics\| PubMed ID: 17666758	2007
Quantitative methods for genome-scale analysis of in situ hybridization and correlation with microarray data. Genome biology\| PubMed ID: 18234097	2008
New developments in sleep research: molecular genetics, gene expression, and systems neurobiology. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19005045	2008
Genomic anatomy of the hippocampus. Neuron\| PubMed ID: 19109908	2008
An anatomic gene expression atlas of the adult mouse brain. Nature neuroscience\| PubMed ID: 19219037	2009
Areal and laminar differentiation in the mouse neocortex using large scale gene expression data. Methods (San Diego, Calif.)\| PubMed ID: 19800006	2010
Surface-based mapping of gene expression and probabilistic expression maps in the mouse cortex. Methods (San Diego, Calif.)\| PubMed ID: 19818854	2010
Shifting the paradigm: new approaches for characterizing and classifying neurons. Current opinion in neurobiology\| PubMed ID: 19896835	2009
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nature neuroscience\| PubMed ID: 20023653	2010
Divergent and nonuniform gene expression patterns in mouse brain. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20956311	2010
Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. The Journal of comparative neurology\| PubMed ID: 21491433	2011
Multi-scale correlation structure of gene expression in the brain. Neural networks : the official journal of the International Neural Network Society\| PubMed ID: 21764550	2011
Transcriptional architecture of the primate neocortex. Neuron\| PubMed ID: 22445337	2012
Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures. Cell\| PubMed ID: 22500809	2012
An anatomically comprehensive atlas of the adult human brain transcriptome. Nature\| PubMed ID: 22996553	2012
Correlated gene expression and target specificity demonstrate excitatory projection neuron diversity. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 24014670	2015
Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development (Cambridge, England)\| PubMed ID: 24154525	2013
The complete genome sequence of a Neanderthal from the Altai Mountains. Nature\| PubMed ID: 24352235	2014
Improving reliability and absolute quantification of human brain microarray data by filtering and scaling probes using RNA-Seq. BMC genomics\| PubMed ID: 24564186	2014
Transcriptional landscape of the prenatal human brain. Nature\| PubMed ID: 24695229	2014
Disruptive CHD8 mutations define a subtype of autism early in development. Cell\| PubMed ID: 24998929	2014
Functional organization of the hippocampal longitudinal axis. Nature reviews. Neuroscience\| PubMed ID: 25234264	2014
Spatial mapping of structural and connectional imaging data for the developing human brain with diffusion tensor imaging. Methods (San Diego, Calif.)\| PubMed ID: 25448302	2015
Convergent transcriptional specializations in the brains of humans and song-learning birds. Science (New York, N.Y.)\| PubMed ID: 25504733	2014
Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin. Molecular psychiatry\| PubMed ID: 25510509	2015
Spatiotemporal dynamics of the postnatal developing primate brain transcriptome. Human molecular genetics\| PubMed ID: 25954031	2015
Canonical genetic signatures of the adult human brain. Nature neuroscience\| PubMed ID: 26571460	2015
Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nature protocols\| PubMed ID: 26890679	2016
Comments and General Discussion on "The Anatomical Problem Posed by Brain Complexity and Size: A Potential Solution". Frontiers in neuroanatomy\| PubMed ID: 27375436	2016
A comprehensive transcriptional map of primate brain development. Nature\| PubMed ID: 27409810	2016
Comprehensive cellular-resolution atlas of the adult human brain. The Journal of comparative neurology\| PubMed ID: 27418273	2016
Biallelic mutations in human DCC cause developmental split-brain syndrome. Nature genetics\| PubMed ID: 28250456	2017
Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation. Neuron\| PubMed ID: 28279351	2017
Fast assembling of neuron fragments in serial 3D sections. Brain informatics\| PubMed ID: 28365869	2017
Transcriptomic Perspectives on Neocortical Structure, Development, Evolution, and Disease. Annual review of neuroscience\| PubMed ID: 28661727	2017
SmartScope2: Simultaneous Imaging and Reconstruction of Neuronal Morphology. Scientific reports\| PubMed ID: 28839271	2017
The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing. Science (New York, N.Y.)\| PubMed ID: 28983044	2017
Neuropathological and transcriptomic characteristics of the aged brain. eLife\| PubMed ID: 29120328	2017
Molecular and cellular reorganization of neural circuits in the human lineage. Science (New York, N.Y.)\| PubMed ID: 29170230	2017
STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array. Scientific reports\| PubMed ID: 29180631	2017
The Human Cell Atlas. eLife\| PubMed ID: 29206104	2017
Cell type discovery and representation in the era of high-content single cell phenotyping. BMC bioinformatics\| PubMed ID: 29322913	2017