Douglas D. Ross

Greenebaum Cancer Center, University of Maryland School of Medicine

Affiliated withUniversity of Maryland School of Medicine Baltimore Va Medical Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2016

Other Publications

Article	Year
Palliative Care Section. Journal of cancer education : the official journal of the American Association for Cancer Education\| PubMed ID: 12092854	2002
Timed sequential therapy of acute leukemia with flavopiridol: in vitro model for a phase I clinical trial. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 12538483	2003
Activity of ascaridol from the anthelmintic herb Chenopodium anthelminticum L. against sensitive and multidrug-resistant tumor cells. Anticancer research\| PubMed ID: 12553060	2002
Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 12616342	2003
Differential effects of the breast cancer resistance protein on the cellular accumulation and cytotoxicity of 9-aminocamptothecin and 9-nitrocamptothecin. Cancer research\| PubMed ID: 12810652	2003
Molecular modes of action of artesunate in tumor cell lines. Molecular pharmacology\| PubMed ID: 12869643	2003
Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport. Cancer research\| PubMed ID: 12874005	2003
Identification of gene expression profiles predicting tumor cell response to L-alanosine. Biochemical pharmacology\| PubMed ID: 12906926	2003
Quantitative analysis of breast cancer resistance protein and cellular resistance to flavopiridol in acute leukemia patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 12960118	2003
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2). Oncogene\| PubMed ID: 14576842	2003
Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic. International journal of cancer\| PubMed ID: 14618629	2004
Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis. Molecular pharmacology\| PubMed ID: 14645676	2003
Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene. Cancer research\| PubMed ID: 14973083	2004
The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. The Journal of biological chemistry\| PubMed ID: 15044468	2004
Liquid chromatography method for the quantitation of the breast cancer resistance protein ABCG2 inhibitor fumitremorgin C and its chemical analogues in mouse plasma and tissues. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 15203030	2004
Mining our ABCs: pharmacogenomic approach for evaluating transporter function in cancer drug resistance. Cancer cell\| PubMed ID: 15324691	2004
Development of required postgraduate palliative care training for internal medicine residents and medical oncology fellows. Journal of cancer education : the official journal of the American Association for Cancer Education\| PubMed ID: 15456662	2004
Modulation of drug resistance transporters as a strategy for treating myelodysplastic syndrome. Best practice & research. Clinical haematology\| PubMed ID: 15494300	2004
Breast cancer resistance protein (BCRP/MXR/ABCG2) in adult acute lymphoblastic leukaemia: frequent expression and possible correlation with shorter disease-free survival. British journal of haematology\| PubMed ID: 15521915	2004
Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference. Molecular cancer therapeutics\| PubMed ID: 15634651	2004
A phase I and pharmacologic study of idarubicin, cytarabine, etoposide, and the multidrug resistance protein (MDR1/Pgp) inhibitor PSC-833 in patients with refractory leukemia. Leukemia research\| PubMed ID: 15661261	2005
The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15994225	2005
Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma. Neoplasia (New York, N.Y.)\| PubMed ID: 16026644	2005
Message for mid-term, 2005. Journal of cancer education : the official journal of the American Association for Cancer Education\| PubMed ID: 16083366	2005
Long-term evaluation of required coursework in palliative and end-of-life care for medical students. Journal of palliative medicine\| PubMed ID: 16238509	2005
Interactive effects of histone deacetylase inhibitors and TRAIL on apoptosis in human leukemia cells: involvement of both death receptor and mitochondrial pathways. International journal of molecular medicine\| PubMed ID: 16273296	2005
Phase I and pharmacokinetic study of flavopiridol followed by 1-beta-D-arabinofuranosylcytosine and mitoxantrone in relapsed and refractory adult acute leukemias. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16322302	2005
Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan. Cancer chemotherapy and pharmacology\| PubMed ID: 16404634	2006
Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression. Blood\| PubMed ID: 16543472	2006
Novel 5' untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: implications for drug resistance, tissue-specific e... Cancer research\| PubMed ID: 16707421	2006
Flavopiridol synergizes TRAIL cytotoxicity by downregulation of FLIPL. Cancer chemotherapy and pharmacology\| PubMed ID: 17187253	2007
Mechanisms of resistance and adaptation to thapsigargin in androgen-independent prostate cancer PC3 and DU145 cells. Archives of biochemistry and biophysics\| PubMed ID: 17475205	2007
Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells. Molecular pharmacology\| PubMed ID: 18042733	2008
The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells. The Journal of biological chemistry\| PubMed ID: 18056989	2008
Experimental design and interaction analysis of combination studies of drugs with log-linear dose responses. Statistics in medicine\| PubMed ID: 18186545	2008
Preclinical studies of vorinostat (suberoylanilide hydroxamic acid) combined with cytosine arabinoside and etoposide for treatment of acute leukemias. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19223502	2009
Suberoylanilide hydroxamic acid (Zolinza/vorinostat) sensitizes TRAIL-resistant breast cancer cells orthotopically implanted in BALB/c nude mice. Molecular cancer therapeutics\| PubMed ID: 19509267	2009
Impact of breast cancer resistance protein on cancer treatment outcomes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19949928	2010
Methods to evaluate transporter activity in cancer. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20419431	2010
Aryl hydrocarbon receptor is a transcriptional activator of the human breast cancer resistance protein (BCRP/ABCG2). Molecular pharmacology\| PubMed ID: 20460431	2010
Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: a possible target for combination therapy with anti-proliferative aminopeptidase inhibitors... Biochemical pharmacology\| PubMed ID: 20510678	2010
A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells. Biochemical pharmacology\| PubMed ID: 20804740	2010
Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924. Molecular cancer therapeutics\| PubMed ID: 21220496	2011
Creative solution for implementation of experiential, competency-based palliative care training for internal medicine residents. Journal of cancer education : the official journal of the American Association for Cancer Education\| PubMed ID: 21553329	2011
Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine. Biochimica et biophysica acta\| PubMed ID: 21718815	2011
Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression. Chinese journal of cancer\| PubMed ID: 22098950	2012
Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance. Biochemical pharmacology\| PubMed ID: 22248732	2012
Dasatinib targets chronic myeloid leukemia-CD34+ progenitors as effectively as it targets mature cells. Haematologica\| PubMed ID: 23065516	2013
Induction of multidrug resistance transporter ABCG2 by prolactin in human breast cancer cells. Molecular pharmacology\| PubMed ID: 23150485	2013
Translational Phase I Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) Combined with Cytarabine and Etoposide in Patients with Relapsed, Refractory, or High-Risk Acute Myeloid Leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23403629	2013
Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1. Biochimica et biophysica acta\| PubMed ID: 24189494	2013
Concomitant bone marrow involvement by plasma cell myeloma and primary myelodysplastic syndrome with biclonal complex chromosome anomalies. Leukemia & lymphoma\| PubMed ID: 25586604	2015
Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/... Biochimica et biophysica acta\| PubMed ID: 25615818	2015