Patrick Pauwels

Molecular Pathology, Antwerp University Hospital (UZA)

Affiliated withAntwerp University Hospital (UZA)Antwerp University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 59	2016

Other Publications

Article	Year
Fluorescence in situ hybridization study of chromosome 7 aberrations in hepatosplenic T-cell lymphoma: isochromosome 7q as a common abnormality accumulating in forms with features of cytolog... Genes, chromosomes & cancer\| PubMed ID: 11807981	2002
Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. Genes, chromosomes & cancer\| PubMed ID: 12112524	2002
Complex genetic alterations in gastrointestinal stromal tumors with autonomic nerve differentiation. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 12118105	2002
Frequent occurrence of BCL6 rearrangements in nodular lymphocyte predominance Hodgkin lymphoma but not in classical Hodgkin lymphoma. Blood\| PubMed ID: 12393409	2003
ALK-ATIC fusion in urinary bladder inflammatory myofibroblastic tumor. Genes, chromosomes & cancer\| PubMed ID: 12939746	2003
Differential expression of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 15154005	2004
Uterine gastrointestinal stromal tumour (GIST). Gynecologic oncology\| PubMed ID: 15943997	2005
Metastasized angiosarcoma of the spleen in a 2-year-old girl. Pediatric hematology and oncology\| PubMed ID: 16020128	2005
Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia. Cancer research\| PubMed ID: 16357161	2005
Inflammatory myofibroblastic tumor with ALK/TPM3 fusion presenting as ileocolic intussusception: an unusual presentation of an unusual neoplasm. Human pathology\| PubMed ID: 16360423	2006
Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients. Human molecular genetics\| PubMed ID: 16461335	2006
Differences in imiquimod treatment outcome in two patients with bowenoid papulosis containing either episomal or integrated human papillomavirus 16. The Journal of investigative dermatology\| PubMed ID: 17008876	2007
One-stage penectomy and phalloplasty for epithelioid sarcoma of the penis in an adolescent. European urology\| PubMed ID: 17095143	2007
Array CGH analysis in primary gastrointestinal stromal tumors: cytogenetic profile correlates with anatomic site and tumor aggressiveness, irrespective of mutational status. Genes, chromosomes & cancer\| PubMed ID: 17171690	2007
Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis. Human pathology\| PubMed ID: 17376510	2007
Absence of lymphangiogenesis in ductal breast cancer at the primary tumor site. Cancer letters\| PubMed ID: 17442484	2007
One-stage penectomy and phalloplasty for epithelioid sarcoma of the penis in an adolescent: part 2. European urology\| PubMed ID: 17575585	2007
Detection of beta-catenin mutations in paraffin-embedded sporadic desmoid-type fibromatosis by mutation-specific restriction enzyme digestion (MSRED): an ancillary diagnostic tool. The American journal of surgical pathology\| PubMed ID: 17721184	2007
Gastrin-releasing peptide receptor imaging in human breast carcinoma versus immunohistochemistry. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 18199617	2008
Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion. Cancer letters\| PubMed ID: 18423981	2008
Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front. Histochemistry and cell biology\| PubMed ID: 18648847	2008
Re: Plexiform angiomyxoid myofibroblastic tumor of the stomach. The American journal of surgical pathology\| PubMed ID: 18824897	2008
Expression of SGLT1, Bcl-2 and p53 in primary pancreatic cancer related to survival. Cancer investigation\| PubMed ID: 18853313	2008
The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment. Current pharmaceutical design\| PubMed ID: 19355975	2009
Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma. Histology and histopathology\| PubMed ID: 19554504	2009
Re: Infrequent SMARCB1/INI1 gene alteration in epithelioid sarcoma: a useful tool in distinguishing epithelioid sarcoma from malignant rhabdoid tumor: Direct evidence of mutational inactivat... Human pathology\| PubMed ID: 19683621	2009
Combined effect of EPO and radiotherapy on the expression of endogenous molecular markers of tumor metabolism and metastasis. Cancer biotherapy & radiopharmaceuticals\| PubMed ID: 19877886	2009
Prognostic role of vasculogenic mimicry in colorectal cancer. Diseases of the colon and rectum\| PubMed ID: 19934926	2009
Carbonic anhydrase IX expression correlates with FDG uptake by primary non-small cell lung cancer. Cancer biotherapy & radiopharmaceuticals\| PubMed ID: 20423227	2010
Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas. BMC cancer\| PubMed ID: 20459770	2010
Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis. Journal of the National Cancer Institute\| PubMed ID: 20484105	2010
Clear-cell variant of solid-pseudopapillary neoplasm of the pancreas: a case report and review of the literature. The Malaysian journal of pathology\| PubMed ID: 20514858	2009
Array-based DNA methylation profiling for breast cancer subtype discrimination. PloS one\| PubMed ID: 20830311	2010
Postextubation obstructive pseudomembranes: a case series and review of a rare complication after endotracheal intubation. Lung\| PubMed ID: 21082188	2011
Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice? Cell transplantation\| PubMed ID: 21092405	2011
The presence of Y chromosomal deoxyribonucleic acid in the female vaginal swab: possible implications for human papillomavirus testing. Cancer epidemiology\| PubMed ID: 21095173	2011
Recognition of cellular implants by the brain's innate immune system. Immunology and cell biology\| PubMed ID: 21102538	2011
MDM2 gene amplification and protein expressions in colon carcinoma: is targeting MDM2 a new therapeutic option? Virchows Archiv : an international journal of pathology\| PubMed ID: 21113617	2011
Relationship between pathological features, HER2 protein expression and HER2 and CEP17 copy number in breast cancer: biological and methodological considerations. Journal of clinical pathology\| PubMed ID: 21177747	2011
Labeling of Luciferase/eGFP-expressing bone marrow-derived stromal cells with fluorescent micron-sized iron oxide particles improves quantitative and qualitative multimodal imaging of cellul... Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 21246293	2011
EGFR in melanoma: clinical significance and potential therapeutic target. Journal of cutaneous pathology\| PubMed ID: 21352258	2011
Current challenges for the advancement of neural stem cell biology and transplantation research. Stem cell reviews\| PubMed ID: 21537994	2012
Immune Cells in Colorectal Cancer: Prognostic Relevance and Role of MSI. Cancer microenvironment : official journal of the International Cancer Microenvironment Society\| PubMed ID: 21618031	2011
Expression and prognostic value of glucose transporters and hexokinases in tonsil and mobile tongue squamous cell carcinoma. Histology and histopathology\| PubMed ID: 21751148	2011
(99)mTc-(CO)(3) His-annexin A5 micro-SPECT demonstrates increased cell death by irinotecan during the vascular normalization window caused by bevacizumab. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22045708	2011
Expression analysis on archival material: comparison of 5 commercially available RNA isolation kits for FFPE material. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 22089347	2011
Tumor cells and tumor-associated macrophages: secreted proteins as potential targets for therapy. Clinical & developmental immunology\| PubMed ID: 22162712	2011
Isolated lung perfusion with gemcitabine combined with radiotherapy: no additional lung toxicity in an experimental model. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 22345281	2012
Incidence and survival trends of uncommon corpus uteri malignancies in the Netherlands, 1989-2008. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society\| PubMed ID: 22398706	2012
Single-photon emission computed tomographic imaging of the early time course of therapy-induced cell death using technetium 99m tricarbonyl His-annexin A5 in a colorectal cancer xenograft mo... Molecular imaging\| PubMed ID: 22469241	2012
Cell type-associated differences in migration, survival, and immunogenicity following grafting in CNS tissue. Cell transplantation\| PubMed ID: 22472278	2012
Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling. Gut\| PubMed ID: 22535374	2013
An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue. The International journal of developmental biology\| PubMed ID: 22811270	2012
EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations. Virchows Archiv : an international journal of pathology\| PubMed ID: 22825000	2012
Quantitative and phenotypic analysis of mesenchymal stromal cell graft survival and recognition by microglia and astrocytes in mouse brain. Immunobiology\| PubMed ID: 22944251	2013
The interaction between ER and NFκB in resistance to endocrine therapy. Breast cancer research : BCR\| PubMed ID: 22963717	2012
Identification of CUX1 as the recurrent chromosomal band 7q22 target gene in human uterine leiomyoma. Genes, chromosomes & cancer\| PubMed ID: 22965931	2013
Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays. PloS one\| PubMed ID: 23094027	2012
Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression. Proteomics\| PubMed ID: 23175172	2013
Expression analysis on archival material revisited: isolation and quantification of RNA extracted from FFPE samples. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 23370428	2013
Smooth muscle cell transplantation improves bladder contractile function in streptozocin-induced diabetic rats. Cytotherapy\| PubMed ID: 23731765	2013
Are erlotinib and gefitinib interchangeable, opposite or complementary for non-small cell lung cancer treatment? Biological, pharmacological and clinical aspects. Critical reviews in oncology/hematology\| PubMed ID: 24041630	2014
Sarcomatous degeneration in fibrous dysplasia of the rib cage. The Annals of thoracic surgery\| PubMed ID: 24088499	2013
Krüppel-like factors in cancer progression: three fingers on the steering wheel. Oncotarget\| PubMed ID: 24429391	2014
Detection of ALK expression in non-small-cell lung cancer with ALK gene rearrangements--comparison of multiple immunohistochemical methods. Histopathology\| PubMed ID: 24621075	2014
Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer. Current pharmaceutical biotechnology\| PubMed ID: 24846062	2014
Mutation analysis of genes in the EGFR pathway in Head and Neck cancer patients: implications for anti-EGFR treatment response. BMC research notes\| PubMed ID: 24899223	2014
Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors. Cancer treatment reviews\| PubMed ID: 24953979	2014
Looking for a new panacea in ALK-rearranged NSCLC: may be Ceritinib? Expert opinion on therapeutic targets\| PubMed ID: 24998601	2014
The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein. BMC cancer\| PubMed ID: 25128202	2014
Immunotherapy: is a minor god yet in the pantheon of treatments for lung cancer? Expert review of anticancer therapy\| PubMed ID: 25148289	2014
Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins. Cancer letters\| PubMed ID: 25192874	2014
The relevance of external quality assessment for molecular testing for ALK positive non-small cell lung cancer: results from two pilot rounds show room for optimization. PloS one\| PubMed ID: 25386659	2014
Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 25436802	2014
Liquid biopsies in lung cancer: the new ambrosia of researchers. Biochimica et biophysica acta\| PubMed ID: 25444714	2014
Circulating tumour cells and lung microvascular tumour cell retention in patients with metastatic breast and cervical cancer. Cancer letters\| PubMed ID: 25449778	2015
The role of cMet in non-small cell lung cancer resistant to EGFR-inhibitors: did we really find the target? Current drug targets\| PubMed ID: 25511614	2014
Improvement in lung cancer outcomes with targeted therapies: an update for family physicians. Journal of the American Board of Family Medicine : JABFM\| PubMed ID: 25567833	2015
Automation of ALK gene rearrangement testing with fluorescence in situ hybridization (FISH): a feasibility study. Experimental and molecular pathology\| PubMed ID: 25576649	2015
Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast ca... Oncoscience\| PubMed ID: 25593984	2014
Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1. Journal of molecular endocrinology\| PubMed ID: 25612765	2015
ALK and crizotinib: after the honeymoon…what else? Resistance mechanisms and new therapies to overcome it. Translational lung cancer research\| PubMed ID: 25806308	2014
cMET in NSCLC: Can We Cut off the Head of the Hydra? From the Pathway to the Resistance. Cancers\| PubMed ID: 25815459	2015
Onartuzumab in lung cancer: the fall of Icarus? Expert review of anticancer therapy\| PubMed ID: 25818471	2015
What can platinum offer yet in the treatment of PS2 NSCLC patients? A systematic review and meta-analysis. Critical reviews in oncology/hematology\| PubMed ID: 25922216	2015
Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer. Oncotarget\| PubMed ID: 25951351	2015
The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer. Oncotarget\| PubMed ID: 26125230	2015
CD44 enhances tumor aggressiveness by promoting tumor cell plasticity. Oncotarget\| PubMed ID: 26189059	2015
Proteomics in cancer research: Are we ready for clinical practice? Critical reviews in oncology/hematology\| PubMed ID: 26277237	2015
Prognostic and Predictive Value of RAS Gene Mutations in Colorectal Cancer: Moving Beyond KRAS Exon 2. Drugs\| PubMed ID: 26347132	2015
Targeting immune checkpoints: New opportunity for mesothelioma treatment? Cancer treatment reviews\| PubMed ID: 26433514	2015
Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect. Journal of immunology research\| PubMed ID: 26605342	2015
TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value. Critical reviews in oncology/hematology\| PubMed ID: 26689115	2016
Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 26728163	2016
Exosomes isolation and characterization in serum is feasible in non-small cell lung cancer patients: critical analysis of evidence and potential role in clinical practice. Oncotarget\| PubMed ID: 26919248	2016
Multicenter Evaluation of a Novel Automated Rapid Detection System of BRAF Status in Formalin-Fixed, Paraffin-Embedded Tissues. The Journal of molecular diagnostics : JMD\| PubMed ID: 26921540	2016
APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines. Cancer letters\| PubMed ID: 26975633	2016
Long-term acquired everolimus resistance in pancreatic neuroendocrine tumours can be overcome with novel PI3K-AKT-mTOR inhibitors. British journal of cancer\| PubMed ID: 26978006	2016
Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using (18)F-FDG PET/CT for Monitoring Treatment Response. Cancer biotherapy & radiopharmaceuticals\| PubMed ID: 27093343	2016