Tomoko Betsuyaku

Division of Pulmonary Medicine, Keio University School of Medicine

Affiliated withKeio University School of Medicine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2016

Other Publications

Article	Year
The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema. American journal of respiratory and critical care medicine\| PubMed ID: 21057003	2011
The role of catalase in pulmonary fibrosis. Respiratory research\| PubMed ID: 21190578	2010
Beta2-adrenergic receptor polymorphisms as a determinant of preferential bronchodilator responses to β2-agonist and anticholinergic agents in Japanese patients with chronic obstructive pulmo... Pharmacogenetics and genomics\| PubMed ID: 21881540	2011
Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoid. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 21979170	2012
Annual change in pulmonary function and clinical phenotype in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine\| PubMed ID: 22016444	2012
Roles of interleukin-17 in an experimental Legionella pneumophila pneumonia model. Infection and immunity\| PubMed ID: 22144493	2012
[A case of elderly advanced squamous cell lung carcinoma successfully treated with nedaplatin and S-1 combination chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 22421773	2012
Sensitivity of heterozygous α1,6-fucosyltransferase knock-out mice to cigarette smoke-induced emphysema: implication of aberrant transforming growth factor-β signaling and matrix metalloprot... The Journal of biological chemistry\| PubMed ID: 22433854	2012
Predictors of osteoporosis and vertebral fractures in patients presenting with moderate-to-severe chronic obstructive lung disease. COPD\| PubMed ID: 22489911	2012
Cytokine profile of bronchoalveolar lavage fluid in patients with combined pulmonary fibrosis and emphysema. Respirology (Carlton, Vic.)\| PubMed ID: 22515655	2012
CRTH2 is a critical regulator of neutrophil migration and resistance to polymicrobial sepsis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22544936	2012
α1,6-Fucosyltransferase (Fut8) is implicated in vulnerability to elastase-induced emphysema in mice and a possible non-invasive predictive marker for disease progression and exacerbations in... Biochemical and biophysical research communications\| PubMed ID: 22732410	2012
Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma. The Journal of allergy and clinical immunology\| PubMed ID: 23006546	2013
Tuberous sclerosis diagnosed by incidental computed tomography findings of multifocal micronodular pneumocyte hyperplasia: a case report. Journal of medical case reports\| PubMed ID: 23072249	2012
Bronchiolar epithelial catalase is diminished in smokers with mild COPD. The European respiratory journal\| PubMed ID: 23100509	2013
Bacillus cereus necrotizing pneumonia in a patient with nephrotic syndrome. Internal medicine (Tokyo, Japan)\| PubMed ID: 23291682	2013
Activation of the FGF2-FGFR1 autocrine pathway: a novel mechanism of acquired resistance to gefitinib in NSCLC. Molecular cancer research : MCR\| PubMed ID: 23536707	2013
DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma. PloS one\| PubMed ID: 23544068	2013
Bone morphogenetic protein receptor type 2 mutations, clinical phenotypes and outcomes of Japanese patients with sporadic or familial pulmonary hypertension. Respirology (Carlton, Vic.)\| PubMed ID: 23675998	2013
Distinguishing between lymphangioleiomyomatosis and carcinomatous peritonitis in a patient with ovarian cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 23752115	2013
Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma. Molecular medicine reports\| PubMed ID: 23759980	2013
[Case report; A case of acute respiratory failure following influenza virus infection successfully treated by direct hemoperfusion using a polymyxin B immobilized fiber column]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine\| PubMed ID: 23767322	2013
A single dose of lipopolysaccharide into mice with emphysema mimics human chronic obstructive pulmonary disease exacerbation as assessed by micro-computed tomography. American journal of respiratory cell and molecular biology\| PubMed ID: 23822858	2013
Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3. Cancer research\| PubMed ID: 23867472	2013
A study to assess COPD Symptom-based Management and to Optimise treatment Strategy in Japan (COSMOS-J) based on GOLD 2011. International journal of chronic obstructive pulmonary disease\| PubMed ID: 24124358	2013
Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation. Nature communications\| PubMed ID: 24157859	2013
Modulation of murine macrophage TLR7/8-mediated cytokine expression by mesenchymal stem cell-conditioned medium. Mediators of inflammation\| PubMed ID: 24191131	2013
A case of skeletal tuberculosis and psoas abscess: disease activity evaluated using (18) F-fluorodeoxyglucose positron emission tomography-computed tomography. BMC medical imaging\| PubMed ID: 24225333	2013
Expression of fibroblast growth factor 9 is associated with poor prognosis in patients with resected non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 24239165	2014
Lung natural killer cells play a major counter-regulatory role in pulmonary vascular hyperpermeability after myocardial infarction. Circulation research\| PubMed ID: 24366170	2014
Combination therapy of 15-epi-lipoxin A4 with antibiotics protects mice from Escherichia coli-induced sepsis*. Critical care medicine\| PubMed ID: 24463858	2014
Analysis of comorbid factors that increase the COPD assessment test scores. Respiratory research\| PubMed ID: 24502760	2014
The efficacy, safety, and pharmacokinetics of biapenem administered thrice daily for the treatment of pneumonia in the elderly. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy\| PubMed ID: 24725621	2014
Dual role of interleukin-23 in epicutaneously-sensitized asthma in mice. Allergology international : official journal of the Japanese Society of Allergology\| PubMed ID: 24809371	2014
Plasma cytokine profiles related to smoking-sensitivity and phenotypes of chronic obstructive pulmonary disease. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals\| PubMed ID: 24842387	2014
Epigenetic clustering of lung adenocarcinomas based on DNA methylation profiles in adjacent lung tissue: Its correlation with smoking history and chronic obstructive pulmonary disease. International journal of cancer\| PubMed ID: 24921089	2014
Pharmacokinetics of arbekacin in bronchial epithelial lining fluid of healthy volunteers. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy\| PubMed ID: 24973909	2014
Claudin-1 is a novel target of miR-375 in non-small-cell lung cancer. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 25001509	2014
Serum (1 → 3) β-D-glucan assay for discrimination between Pneumocystis jirovecii pneumonia and colonization. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy\| PubMed ID: 25066434	2014
Determinants of Long-Term Persistence with Tiotropium Bromide for Chronic Obstructive Pulmonary Disease. COPD\| PubMed ID: 25093464	2015
Multiple roles of extracellular fibroblast growth factors in lung cancer cells. International journal of oncology\| PubMed ID: 25353145	2015
Long‑term exposure to gefitinib induces acquired resistance through DNA methylation changes in the EGFR‑mutant PC9 lung cancer cell line. International journal of oncology\| PubMed ID: 25353970	2015
Polymorphism of LRP5 gene and emphysema severity are associated with osteoporosis in Japanese patients with or at risk for COPD. Respirology (Carlton, Vic.)\| PubMed ID: 25392953	2015
Characterization of the cell of origin and propagation potential of the fibroblast growth factor 9-induced mouse model of lung adenocarcinoma. The Journal of pathology\| PubMed ID: 25413587	2015
Methylation-induced downregulation of TFPI-2 causes TMPRSS4 overexpression and contributes to oncogenesis in a subset of non-small-cell lung carcinoma. Cancer science\| PubMed ID: 25414083	2015
Comparison of the immunogenicity and safety of polysaccharide and protein-conjugated pneumococcal vaccines among the elderly aged 80 years or older in Japan: an open-labeled randomized study... Vaccine\| PubMed ID: 25448102	2015
Pulmonary nocardiosis caused by Nocardia cyriacigeorgica in patients with Mycobacterium avium complex lung disease: two case reports. BMC infectious diseases\| PubMed ID: 25491030	2014
FOXD1 expression is associated with poor prognosis in non-small cell lung cancer. Anticancer research\| PubMed ID: 25550559	2015
A phase II study of biweekly paclitaxel and carboplatin in elderly patients with advanced non-small cell lung cancer. Cancer chemotherapy and pharmacology\| PubMed ID: 25563719	2015
A Phase II study of S-1 and irinotecan combination therapy in previously treated patients with advanced non-small cell lung cancer. Japanese journal of clinical oncology\| PubMed ID: 25612761	2015
The diagnostic usefulness of 18F-fluorodoxyglucose-positron emission tomography/CT in SAPHO syndrome. BMJ case reports\| PubMed ID: 25733097	2015
Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 25820526	2015
Phenotype of asthma related with high serum periostin levels. Allergology international : official journal of the Japanese Society of Allergology\| PubMed ID: 25838094	2015
Attenuation of lipopolysaccharide-induced acute lung injury after (pro)renin receptor blockade. Experimental lung research\| PubMed ID: 25844689	2015
Correlation of a decline in aerobic capacity with development of emphysema in patients with chronic obstructive pulmonary disease: a prospective observational study. PloS one\| PubMed ID: 25909949	2015
Mimicking the niche of lung epithelial stem cells and characterization of several effectors of their in vitro behavior. Stem cell research\| PubMed ID: 26042794	2015
The reasons for triple therapy in stable COPD patients in Japanese clinical practice. International journal of chronic obstructive pulmonary disease\| PubMed ID: 26082629	2015
A Case of Disseminated Cryptococcal Infection and Concurrent Lung Tuberculosis in a Patient under Steroid Therapy for Interstitial Pneumonia. Case reports in pulmonology\| PubMed ID: 26124974	2015
Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer. Oncology reports\| PubMed ID: 26134684	2015
Fournier's gangrene: a surgical emergency. Infection\| PubMed ID: 26138056	2016
Fatal Fulminant Pneumonia Caused by Methicillin-Sensitive Staphylococcus aureus Negative for Major High-Virulence Factors Following Influenza B Virus Infection. The American journal of case reports\| PubMed ID: 26171835	2015
Immune reconstitution inflammatory syndrome due to Mycobacterium avium complex successfully followed up using 18 F-fluorodeoxyglucose positron emission tomography-computed tomography in a pa... BMC medical imaging\| PubMed ID: 26187282	2015
Distinct effects of endogenous interleukin-23 on eosinophilic airway inflammation in response to different antigens. Allergology international : official journal of the Japanese Society of Allergology\| PubMed ID: 26344076	2015
Theory and strategy for Pneumococcal vaccines in the elderly. Human vaccines & immunotherapeutics\| PubMed ID: 26406267	2016
Blue-Black Trachea as a Result of Minocycline-induced Hyperpigmentation. American journal of respiratory and critical care medicine\| PubMed ID: 26426678	2016
Successful resumption of tocilizumab for rheumatoid arthritis after resection of a pulmonary Mycobacterium avium complex lesion: a case report. BMC pulmonary medicine\| PubMed ID: 26496968	2015
Dry pleurisy complicating solitary pulmonary nodules caused by Mycobacterium avium: a case report. Journal of medical case reports\| PubMed ID: 26503229	2015
In vitro modeling to determine mutation specificity of EGFR tyrosine kinase inhibitors against clinically relevant EGFR mutants in non-small-cell lung cancer. Oncotarget\| PubMed ID: 26515464	2015
The chronic obstructive pulmonary disease comorbidity spectrum in Japan differs from that in western countries. Respiratory investigation\| PubMed ID: 26521103	2015
Pneumococcal Infection Aggravates Elastase-Induced Emphysema via Matrix Metalloproteinase 12 Overexpression. The Journal of infectious diseases\| PubMed ID: 26563237	2016
Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses. Nature immunology\| PubMed ID: 26595888	2016
Health-related quality of life is inversely correlated with C-reactive protein and age in Mycobacterium avium complex lung disease: a cross-sectional analysis of 235 patients. Respiratory research\| PubMed ID: 26635226	2015
Activation of EGFR Bypass Signaling by TGFα Overexpression Induces Acquired Resistance to Alectinib in ALK-Translocated Lung Cancer Cells. Molecular cancer therapeutics\| PubMed ID: 26682573	2016
Determinants of chronic obstructive pulmonary disease severity in the late-elderly differ from those in younger patients. BMC research notes\| PubMed ID: 26728686	2016
Disseminated Mycobacterium marinum Infection With a Destructive Nasal Lesion Mimicking Extranodal NK/T Cell Lymphoma: A Case Report. Medicine\| PubMed ID: 26986167	2016
Mechanisms to Suppress ILC2-induced Airway Inflammation. Annals of the American Thoracic Society\| PubMed ID: 27027961	2016
The association between dental health and nutritional status in chronic obstructive pulmonary disease. Chronic respiratory disease\| PubMed ID: 27056058	2016
Levels of Soluble Receptor for Advanced Glycation End Products in Bronchoalveolar Lavage Fluid in Patients with Various Inflammatory Lung Diseases. Clinical medicine insights. Circulatory, respiratory and pulmonary medicine\| PubMed ID: 27147899	2015