Hideyuki Takeshima

Department of Respiratory Medicine, The University of Tokyo Hospital

Affiliated withThe University of Tokyo Hospital

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2016

Other Publications

Article	Year
Fabrication of wool keratin sponge scaffolds for long-term cell cultivation. Journal of biotechnology\| PubMed ID: 11738723	2002
Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b. Journal of biochemistry\| PubMed ID: 12869530	2003
DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction. The Journal of biological chemistry\| PubMed ID: 15105426	2004
Distinct DNA methylation activity of Dnmt3a and Dnmt3b towards naked and nucleosomal DNA. Journal of biochemistry\| PubMed ID: 16567415	2006
Mouse Dnmt3a preferentially methylates linker DNA and is inhibited by histone H1. Journal of molecular biology\| PubMed ID: 18823905	2008
The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands. Genome research\| PubMed ID: 19652013	2009
Development of a novel output value for quantitative assessment in methylated DNA immunoprecipitation-CpG island microarray analysis. DNA research : an international journal for rapid publication of reports on genes and genomes\| PubMed ID: 19767598	2009
Methylation destiny: Moira takes account of histones and RNA polymerase II. Epigenetics\| PubMed ID: 20160507	2010
Hippocampal epigenetic modification at the brain-derived neurotrophic factor gene induced by an enriched environment. Hippocampus\| PubMed ID: 20232397	2011
Enhanced IL-1beta production in response to the activation of hippocampal glial cells impairs neurogenesis in aged mice. Synapse (New York, N.Y.)\| PubMed ID: 20336624	2010
Hippocampal epigenetic modification at the doublecortin gene is involved in the impairment of neurogenesis with aging. Synapse (New York, N.Y.)\| PubMed ID: 20340168	2010
Epigenetic modulation at the CCR2 gene correlates with the maintenance of behavioral sensitization to methamphetamine. Addiction biology\| PubMed ID: 20624155	2010
Characterization of DNA-binding activity in the N-terminal domain of the DNA methyltransferase Dnmt3a. The Biochemical journal\| PubMed ID: 21510846	2011
Effects of genome architecture and epigenetic factors on susceptibility of promoter CpG islands to aberrant DNA methylation induction. Genomics\| PubMed ID: 21683780	2011
Development of a novel approach, the epigenome-based outlier approach, to identify tumor-suppressor genes silenced by aberrant DNA methylation. Cancer letters\| PubMed ID: 22433712	2012
[Application of epigenetics to cancer diagnosis and therapy]. Nihon Geka Gakkai zasshi\| PubMed ID: 22582579	2012
Induction of aberrant trimethylation of histone H3 lysine 27 by inflammation in mouse colonic epithelial cells. Carcinogenesis\| PubMed ID: 22976929	2012
Comprehensive DNA methylation and extensive mutation analyses reveal an association between the CpG island methylator phenotype and oncogenic mutations in gastric cancers. Cancer letters\| PubMed ID: 23196062	2013
Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain. Brain : a journal of neurology\| PubMed ID: 23364351	2013
[Epigenetics as a novel therapeutic target of cancer]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 24231695	2013
Usefulness of low-dose methotrexate monotherapy for treating sarcoidosis. Internal medicine (Tokyo, Japan)\| PubMed ID: 24334575	2013
Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association\| PubMed ID: 24510342	2015
Frequent involvement of chromatin remodeler alterations in gastric field cancerization. Cancer letters\| PubMed ID: 25462860	2015
Identification of coexistence of DNA methylation and H3K27me3 specifically in cancer cells as a promising target for epigenetic therapy. Carcinogenesis\| PubMed ID: 25477340	2015
Establishment of a DNA methylation marker to evaluate cancer cell fraction in gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association\| PubMed ID: 25678126	2016
Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells. PloS one\| PubMed ID: 26505478	2015
[Case Report; Influenza vaccination-associated acute lung injury: two cases report]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine\| PubMed ID: 26513964	2015
Early-Stage Induction of SWI/SNF Mutations during Esophageal Squamous Cell Carcinogenesis. PloS one\| PubMed ID: 26812616	2016