Marc Symons

The Feinstein Institute for Medical Research at North Shore-LIJ

Affiliated withThe Feinstein Institute for Medical Research at North Shore-LIJ

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 19	2016

Other Publications

Article	Year
Microglial stimulation of glioblastoma invasion involves EGFR and CSF-1R signaling. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 22294205	2012
Regulation of microtubule stability and mitotic progression by survivin. Cancer research\| PubMed ID: 11980633	2002
Role of Rho family GTPases in epithelial morphogenesis. Genes & development\| PubMed ID: 12000787	2002
Cell motility and invasion assays. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12094581	2002
Synaptojanin 2 functions at an early step of clathrin-mediated endocytosis. Current biology : CB\| PubMed ID: 12699622	2003
Control of vesicular trafficking by Rho GTPases. Current biology : CB\| PubMed ID: 12747855	2003
Cyclin D1 governs adhesion and motility of macrophages. Molecular biology of the cell\| PubMed ID: 12802071	2003
Regulation of migration of primary prostate epithelial cells by secreted factors from prostate stromal cells. Experimental cell research\| PubMed ID: 12915116	2003
Modulation of Rac localization and function by dynamin. Molecular biology of the cell\| PubMed ID: 14617821	2004
Molecular basis for Rho GTPase signaling specificity. Breast cancer research and treatment\| PubMed ID: 14999155	2004
Regulation of anoikis by Cdc42 and Rac1. Experimental cell research\| PubMed ID: 15093747	2004
Role of synaptojanin 2 in glioma cell migration and invasion. Cancer research\| PubMed ID: 15548694	2004
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin. The Journal of cell biology\| PubMed ID: 15684033	2005
Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection. Oncogene\| PubMed ID: 15688034	2005
Rho GTPase-dependent signaling is required for macrophage migration inhibitory factor-mediated expression of cyclin D1. The Journal of biological chemistry\| PubMed ID: 15840582	2005
Role of Rho family GTPases in CCR1- and CCR5-induced actin reorganization in macrophages. Biochemical and biophysical research communications\| PubMed ID: 15882964	2005
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion. Oncogene\| PubMed ID: 16027728	2005
Cell migration and invasion assays. Methods (San Diego, Calif.)\| PubMed ID: 16288884	2005
Molecular pathways triggering glioma cell invasion. Expert review of molecular diagnostics\| PubMed ID: 16824034	2006
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome. Cancer research\| PubMed ID: 17018610	2006
The atypical Rho family GTPase Wrch-1 regulates focal adhesion formation and cell migration. Journal of cell science\| PubMed ID: 17504809	2007
Up-regulation of Rac1 by epidermal growth factor mediates COX-2 expression in recurrent respiratory papillomas. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 17592548	2007
The GTPase Rac regulates the proliferation and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 17622308	2007
The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration. Journal of cell science\| PubMed ID: 17698922	2007
Role of myosin II activity and the regulation of myosin light chain phosphorylation in astrocytomas. Cell motility and the cytoskeleton\| PubMed ID: 17896341	2008
RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells. Experimental cell research\| PubMed ID: 18316075	2008
Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms. Molecular and cellular biology\| PubMed ID: 18411304	2008
The arthritis severity locus Cia5d is a novel genetic regulator of the invasive properties of synovial fibroblasts. Arthritis and rheumatism\| PubMed ID: 18668563	2008
Cell biology: watching the first steps of podosome formation. Current biology : CB\| PubMed ID: 18957242	2008
The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma. The American journal of pathology\| PubMed ID: 19008376	2008
Rac and Rho driving tumor invasion: who's at the wheel? Genome biology\| PubMed ID: 19291272	2009
Role of Rac1-regulated signaling in medulloblastoma invasion. Laboratory investigation. Journal of neurosurgery. Pediatrics\| PubMed ID: 19645540	2009
Pak1 and Pak2 are activated in recurrent respiratory papillomas, contributing to one pathway of Rac1-mediated COX-2 expression. International journal of cancer\| PubMed ID: 20131316	2010
Phosphoinositides direct equine infectious anemia virus gag trafficking and release. Traffic (Copenhagen, Denmark)\| PubMed ID: 21176037	2011
The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy. Drug discovery today\| PubMed ID: 21262381	2011
Rac1 activation comes full circle. The EMBO journal\| PubMed ID: 21975373	2011
Glioblastoma with PNET-like components has a higher frequency of isocitrate dehydrogenase 1 (IDH1) mutation and likely a better prognosis than primary glioblastoma. International journal of clinical and experimental pathology\| PubMed ID: 22076165	2011
Role of a DNA damage checkpoint pathway in ionizing radiation-induced glioblastoma cell migration and invasion. Cellular and molecular neurobiology\| PubMed ID: 22552889	2012
Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells. Molecular cancer research : MCR\| PubMed ID: 22571869	2012
Signaling determinants of glioma cell invasion. Advances in experimental medicine and biology\| PubMed ID: 22879067	2013
The small GTPase RhoG mediates glioblastoma cell invasion. Molecular cancer\| PubMed ID: 22966858	2012
Regulation of synaptojanin 2 5'-phosphatase activity by Src. Cell adhesion & migration\| PubMed ID: 23076136	2012
The MLK-related kinase (MRK) is a novel RhoC effector that mediates lysophosphatidic acid (LPA)-stimulated tumor cell invasion. The Journal of biological chemistry\| PubMed ID: 23319595	2013
The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast gr... The Journal of biological chemistry\| PubMed ID: 23775076	2013
Implications of Rho GTPase Signaling in Glioma Cell Invasion and Tumor Progression. Frontiers in oncology\| PubMed ID: 24109588	2013
The regulation of RhoA at focal adhesions by StarD13 is important for astrocytoma cell motility. Experimental cell research\| PubMed ID: 24333506	2014
Semapimod sensitizes glioblastoma tumors to ionizing radiation by targeting microglia. PloS one\| PubMed ID: 24816734	2014
Repurposing mebendazole for the treatment of medulloblastoma. Neurosurgery\| PubMed ID: 25594199	2015
Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer. Science signaling\| PubMed ID: 25605973	2015
Celecoxib inhibits Ewing sarcoma cell migration via actin modulation. The Journal of surgical research\| PubMed ID: 25934222	2015
The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation. PloS one\| PubMed ID: 26709919	2015
SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide. Molecular cancer research : MCR\| PubMed ID: 26764186	2016
Neuro-oncology biotech industry progress report. Journal of neuro-oncology\| PubMed ID: 26897014	2016
Radioresistance of Brain Tumors. Cancers\| PubMed ID: 27043632	2016
Pharmacological Inhibition of the Protein Kinase MRK/ZAK Radiosensitizes Medulloblastoma. Molecular cancer therapeutics\| PubMed ID: 27207779	2016
Curcumin changes the polarity of tumor-associated microglia and eliminates glioblastoma. International journal of cancer\| PubMed ID: 27543754	2016