James D. Orth

Department of Molecular, University of Colorado, Boulder

Affiliated withUniversity of Colorado, Boulder

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 13	2016

Other Publications

Article	Year
The large GTPase dynamin regulates actin comet formation and movement in living cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11782546	2002
Dynamin at the actin-membrane interface. Current opinion in cell biology\| PubMed ID: 12517701	2003
Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis. Molecular and cellular biology\| PubMed ID: 12612086	2003
A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells. Molecular biology of the cell\| PubMed ID: 12631725	2003
Cdc42 and the actin-related protein/neural Wiskott-Aldrich syndrome protein network mediate cellular invasion by Cryptosporidium parvum. Infection and immunity\| PubMed ID: 15102814	2004
Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nature reviews. Molecular cell biology\| PubMed ID: 15366708	2004
Caveolin-1 interacts directly with dynamin-2. Journal of molecular biology\| PubMed ID: 15811383	2005
Actin and Arf1-dependent recruitment of a cortactin-dynamin complex to the Golgi regulates post-Golgi transport. Nature cell biology\| PubMed ID: 15821732	2005
A novel endocytic mechanism of epidermal growth factor receptor sequestration and internalization. Cancer research\| PubMed ID: 16585185	2006
Get off my back! Rapid receptor internalization through circular dorsal ruffles. Cancer research\| PubMed ID: 17145849	2006
Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer research\| PubMed ID: 18451153	2008
Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Molecular cancer therapeutics\| PubMed ID: 18974392	2008
Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer cell\| PubMed ID: 19800579	2009
An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor. PloS one\| PubMed ID: 19802393	2009
Cell death when the SAC is out of commission. Cell cycle (Georgetown, Tex.)\| PubMed ID: 20559025	2010
Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics. Cancer research\| PubMed ID: 21712408	2011
Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells. Cancer letters\| PubMed ID: 21782324	2011
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction. Molecular biology of the cell\| PubMed ID: 22171325	2012
Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin. Science translational medicine\| PubMed ID: 25378644	2014
In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy. Nature methods\| PubMed ID: 25867850	2015
Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor. Scientific reports\| PubMed ID: 26399741	2015