Christian Schwerk

Department of Pediatrics, Heidelberg University

Research Area

Biography

Christian Schwerk has not added Biography.
If you are Christian Schwerk and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 45	2016
Publication title Cited by 15	2019
Publication title	2025

Other Publications

Article	Year
TNFalpha induces choroid plexus epithelial cell barrier alterations by apoptotic and nonapoptotic mechanisms. Journal of biomedicine & biotechnology\| PubMed ID: 20369072	2010
Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold. RNA (New York, N.Y.)\| PubMed ID: 20966198	2010
Transcellular migration of neutrophil granulocytes through the blood-cerebrospinal fluid barrier after infection with Streptococcus suis. Journal of neuroinflammation\| PubMed ID: 21592385	2011
In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis: release of pro-inflammatory cytokines and chemokines. Microbes and infection / Institut Pasteur\| PubMed ID: 21683799	2011
Polar invasion and translocation of Neisseria meningitidis and Streptococcus suis in a novel human model of the blood-cerebrospinal fluid barrier. PloS one\| PubMed ID: 22253884	2012
A novel porcine in vitro model of the blood-cerebrospinal fluid barrier with strong barrier function. PloS one\| PubMed ID: 22745832	2012
Chemotaxis of T-cells after infection of human choroid plexus papilloma cells with Echovirus 30 in an in vitro model of the blood-cerebrospinal fluid barrier. Virus research\| PubMed ID: 23000117	2012
Culture models to study leukocyte trafficking across the choroid plexus. Fluids and barriers of the CNS\| PubMed ID: 23305147	2013
The surface proteins InlA and InlB are interdependently required for polar basolateral invasion by Listeria monocytogenes in a human model of the blood-cerebrospinal fluid barrier. Microbes and infection / Institut Pasteur\| PubMed ID: 23376167	2013
Transmigration of polymorphnuclear neutrophils and monocytes through the human blood-cerebrospinal fluid barrier after bacterial infection in vitro. Journal of neuroinflammation\| PubMed ID: 23448224	2013
Neisseria meningitidis elicits a pro-inflammatory response involving IκBζ in a human blood-cerebrospinal fluid barrier model. Journal of neuroinflammation\| PubMed ID: 25347003	2014
Impact of calcium signaling during infection of Neisseria meningitidis to human brain microvascular endothelial cells. PloS one\| PubMed ID: 25464500	2014
The choroid plexus-a multi-role player during infectious diseases of the CNS. Frontiers in cellular neuroscience\| PubMed ID: 25814932	2015
The choroid plexus may be an underestimated site of tumor invasion to the brain: an in vitro study using neuroblastoma cell lines. Cancer cell international\| PubMed ID: 26500454	2015
Neuroinvasion and Inflammation in Viral Central Nervous System Infections. Mediators of inflammation\| PubMed ID: 27313404	2016
Biological activities of suilysin: role in Streptococcus suis pathogenesis. Future microbiology\| PubMed ID: 27357518	2016
Mitogen-activated protein kinases are required for effective infection of human choroid plexus epithelial cells by Listeria monocytogenes. Microbes and infection\| PubMed ID: 27671041	2017
Sequential transmigration of polymorphonuclear cells and naive CD3 T lymphocytes across the blood-cerebrospinal-fluid barrier in vitro following infection with Echovirus 30. Virus research\| PubMed ID: 28161477	2017
Muramidase-released protein of Streptococcus suis: New insight into its impact on virulence. Virulence\| PubMed ID: 28467144	2017
Experimental Porcine Infection as a Representative Model for Human Toxoplasmosis. Mediators of inflammation\| PubMed ID: 28883687	2017
Interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell... Immunologic research\| PubMed ID: 28913776	2017
The diverse cellular responses of the choroid plexus during infection of the central nervous system. American journal of physiology. Cell physiology\| PubMed ID: 29070490	2018
Strain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier. Journal of neuroinflammation\| PubMed ID: 29463289	2018
Capsule and fimbriae modulate the invasion of Haemophilus influenzae in a human blood-cerebrospinal fluid barrier model. International journal of medical microbiology : IJMM\| PubMed ID: 30049648	2018
Virulence factor-dependent basolateral invasion of choroid plexus epithelial cells by pathogenic Escherichia coli in vitro. FEMS microbiology letters\| PubMed ID: 30476042	2018
Optimized cultivation of porcine choroid plexus epithelial cells, a blood-cerebrospinal fluid barrier model, for studying granulocyte transmigration. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 30996296	2019
Review of functional in vitro models of the blood-cerebrospinal fluid barrier in leukaemia research. Journal of neuroscience methods\| PubMed ID: 31669338	2020
Virulence Factors of Meningitis-Causing Bacteria: Enabling Brain Entry across the Blood-Brain Barrier. International journal of molecular sciences\| PubMed ID: 31671896	2019
Distinct migratory pattern of naive and effector T cells through the blood-CSF barrier following Echovirus 30 infection. Journal of neuroinflammation\| PubMed ID: 31752904	2019
Bitter taste receptors profiling in the human blood-cerebrospinal fluid-barrier. Biochemical pharmacology\| PubMed ID: 32251676	2020
The bitter taste receptor TAS2R14 regulates resveratrol transport across the human blood-cerebrospinal fluid barrier. Biochemical pharmacology\| PubMed ID: 32272108	2020
Potential Roles and Functions of Listerial Virulence Factors during Brain Entry. Toxins\| PubMed ID: 32380697	2020
From Gene to Protein-How Bacterial Virulence Factors Manipulate Host Gene Expression During Infection. International journal of molecular sciences\| PubMed ID: 32466312	2020
Role of Bacterial and Host DNases on Host-Pathogen Interaction during Meningitis. International journal of molecular sciences\| PubMed ID: 32722502	2020
Non-Typeable Invade Choroid Plexus Epithelial Cells in a Polar Fashion. International journal of molecular sciences\| PubMed ID: 32785145	2020
Cadaverine and Spermine Elicit Ca Uptake in Human CP Cells via a Trace Amine-Associated Receptor 1 Dependent Pathway. Journal of molecular neuroscience : MN\| PubMed ID: 32816235	2021
Polar Infection of Echovirus-30 Causes Differential Barrier Affection and Gene Regulation at the Blood-Cerebrospinal Fluid Barrier. International journal of molecular sciences\| PubMed ID: 32872518	2020
Interactions and Signal Transduction Pathways Involved during Central Nervous System Entry by across the Blood-Brain Barriers. International journal of molecular sciences\| PubMed ID: 33233688	2020
Echovirus-30 Infection Alters Host Proteins in Lipid Rafts at the Cerebrospinal Fluid Barrier In Vitro. Microorganisms\| PubMed ID: 33321840	2020
The Choroid Plexus Is Permissive for a Preactivated Antigen-Experienced Memory B-Cell Subset in Multiple Sclerosis. Frontiers in immunology\| PubMed ID: 33574821	2020
Effect of Lipopolysaccharide-Induced Inflammatory Challenge on β-Glucuronidase Activity and the Concentration of Quercetin and Its Metabolites in the Choroid Plexus, Blood Plasma and Cerebro... International journal of molecular sciences\| PubMed ID: 34281178	2021
Invasion of the choroid plexus epithelium by Neisseria meningitidis is differently mediated by Arp2/3 signaling and possibly by dynamin dependent on the presence of the capsule. Pathogens and disease\| PubMed ID: 34410374	2021
Capsule-dependent impact of MAPK signalling on host cell invasion and immune response during infection of the choroid plexus epithelium by Neisseria meningitidis. Fluids and barriers of the CNS\| PubMed ID: 34863201	2021
Transmigration of across an blood-cerebrospinal fluid barrier. iScience\| PubMed ID: 35313698	2022
Porcine choroid plexus-Riems cell line demonstrates altered polarization of transport proteins compared with the native epithelium. American journal of physiology. Cell physiology\| PubMed ID: 35508188	2022
Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type model of the choroid plexus. iScience\| PubMed ID: 35633941	2022
Cross-sectional seroprevalence surveys of SARS-CoV-2 antibodies in children in Germany, June 2020 to May 2021. Nature communications\| PubMed ID: 35668073	2022
Characterization of TRPV4-mediated signaling pathways in an optimized human choroid plexus epithelial cell line. American journal of physiology. Cell physiology\| PubMed ID: 35938676	2022
In Vitro Models of the Blood-Cerebrospinal Fluid Barrier and Their Applications in the Development and Research of (Neuro)Pharmaceuticals. Pharmaceutics\| PubMed ID: 36015358	2022
Protocol to analyze the transmigration efficiency of T. brucei using an in vitro model of the blood-cerebrospinal fluid barrier. STAR protocols\| PubMed ID: 36103307	2022
Different Involvement of Vimentin during Invasion by at the Blood-Brain and the Blood-Cerebrospinal Fluid Barriers In Vitro. International journal of molecular sciences\| PubMed ID: 36361697	2022
Protocol for the setup and use of a human choroid plexus endothelial-epithelial two-cell-type model. STAR protocols\| PubMed ID: 36386888	2022
The role of PLVAP in endothelial cells. Cell and tissue research\| PubMed ID: 36781482	2023
The phosphoproteome of choroid plexus epithelial cells following infection with Neisseria meningitidis. Frontiers in cellular and infection microbiology\| PubMed ID: 37065199	2023
Corrigendum: The phosphoproteome of choroid plexus epithelial cells following infection with Neisseria meningitidis. Frontiers in cellular and infection microbiology\| PubMed ID: 37637459	2023
Editorial: Host-pathogen interactions at the blood-brain barriers. Frontiers in cellular and infection microbiology\| PubMed ID: 38720959	2024
In vitro models of the choroid plexus and the blood-cerebrospinal fluid barrier: advances, applications, and perspectives. Human cell\| PubMed ID: 39103559	2024
Activation of Wnt/β-catenin signaling is critical for the tumorigenesis of choroid plexus. Neuro-oncology\| PubMed ID: 39215664	2025
Transcriptome and Functional Comparison of Primary and Immortalized Endothelial Cells of the Human Choroid Plexus at the Blood-Cerebrospinal Fluid Barrier. International journal of molecular sciences\| PubMed ID: 40004242	2025
A pH-sensitive binding modality allows successful transferrin receptor-mediated transcytosis of a bivalent antibody across brain barriers. mAbs\| PubMed ID: 40983601	2025
Genotype-dependent cell tropism of EV-A71 at the human blood cerebrospinal fluid and blood brain barrier. Microbial pathogenesis\| PubMed ID: 41135722	2025