Massimo Negrini

Department of Morphology, University of ferrara

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 10	2016

Other Publications

Article	Year
Late appearance of the 11q22.3-23.1 deletion involving the ATM locus in B-cell chronic lymphocytic leukemia and related disorders. Clinico-biological significance. Haematologica\| PubMed ID: 11801464	2002
Loss of methylation at chromosome 11p15.5 is common in human adult tumors. Oncogene\| PubMed ID: 11971191	2002
NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15). Blood\| PubMed ID: 11986249	2002
Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors. Oncogene\| PubMed ID: 12370818	2002
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12434020	2002
Genetic chaos and antichaos in human cancers. Medical hypotheses\| PubMed ID: 12606244	2003
Human homeobox gene HOXC13 is the partner of NUP98 in adult acute myeloid leukemia with t(11;12)(p15;q13). Genes, chromosomes & cancer\| PubMed ID: 12619167	2003
Oncogenic transformation by BK virus and association with human tumors. Oncogene\| PubMed ID: 12910256	2003
The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14504409	2003
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14973191	2004
Simian virus 40 infection in humans and association with human diseases: results and hypotheses. Virology\| PubMed ID: 15015494	2004
Multigene methylation analysis of gastrointestinal tumors: TPEF emerges as a frequent tumor-specific aberrantly methylated marker that can be detected in peripheral blood. Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology\| PubMed ID: 15068392	2003
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15210942	2004
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15284443	2004
Cryptic insertion producing two NUP98/NSD1 chimeric transcripts in adult refractory anemia with an excess of blasts. Genes, chromosomes & cancer\| PubMed ID: 15382262	2004
Frequent aberrant methylation of the CDH4 gene promoter in human colorectal and gastric cancer. Cancer research\| PubMed ID: 15548679	2004
Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15701871	2005
Familial cancer associated with a polymorphism in ARLTS1. The New England journal of medicine\| PubMed ID: 15843669	2005
MicroRNA gene expression deregulation in human breast cancer. Cancer research\| PubMed ID: 16103053	2005
miR-15 and miR-16 induce apoptosis by targeting BCL2. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16166262	2005
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. The New England journal of medicine\| PubMed ID: 16251535	2005
Neoplastic circulating endothelial cells in multiple myeloma with 13q14 deletion. Blood\| PubMed ID: 16317105	2006
Identification of NUP98 abnormalities in acute leukemia: JARID1A (12p13) as a new partner gene. Genes, chromosomes & cancer\| PubMed ID: 16419055	2006
A microRNA expression signature of human solid tumors defines cancer gene targets. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16461460	2006
BK virus, JC virus and Simian Virus 40 infection in humans, and association with human tumors. Advances in experimental medicine and biology\| PubMed ID: 16626046	2006
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer. Cancer research\| PubMed ID: 17079447	2006
Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas. Journal of cellular physiology\| PubMed ID: 17111382	2007
Mechanisms causing imprinting defects in familial Beckwith-Wiedemann syndrome with Wilms' tumour. Human molecular genetics\| PubMed ID: 17158821	2007
A microRNA signature of hypoxia. Molecular and cellular biology\| PubMed ID: 17194750	2007
Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer. Molecular cancer\| PubMed ID: 17328794	2007
MicroRNAs in human cancer: from research to therapy. Journal of cell science\| PubMed ID: 17515481	2007
Regulation of microRNA expression: the hypoxic component. Cell cycle (Georgetown, Tex.)\| PubMed ID: 17582223	2007
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer research\| PubMed ID: 17616664	2007
Regulatory mechanisms of microRNAs involvement in cancer. Expert opinion on biological therapy\| PubMed ID: 17665990	2007
Tumor suppressor functions of ARLTS1 in lung cancers. Cancer research\| PubMed ID: 17699778	2007
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer. Molecular cancer\| PubMed ID: 17716371	2007
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer cell\| PubMed ID: 17785203	2007
Micro-RNA profiling in kidney and bladder cancers. Urologic oncology\| PubMed ID: 17826655	2007
E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer cell\| PubMed ID: 18328430	2008
MiR-15a and miR-16-1 cluster functions in human leukemia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18362358	2008
Breast cancer metastasis: a microRNA story. Breast cancer research : BCR\| PubMed ID: 18373886	2008
Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Experimental hematology\| PubMed ID: 18504067	2008
Genome wide identification of recessive cancer genes by combinatorial mutation analysis. PloS one\| PubMed ID: 18846217	2008
MicroRNA expression changes during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal, a product of lipid peroxidation. Free radical biology & medicine\| PubMed ID: 19022373	2009
MicroRNA involvement in hepatocellular carcinoma. Journal of cellular and molecular medicine\| PubMed ID: 19120703	2008
MicroRNAs and cancer--new paradigms in molecular oncology. Current opinion in cell biology\| PubMed ID: 19411171	2009
MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells. Cancer research\| PubMed ID: 19584283	2009
MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19671867	2009
Karyotype-specific microRNA signature in chronic lymphocytic leukemia. Blood\| PubMed ID: 19717645	2009
MicroRNA fingerprints identify miR-150 as a plasma prognostic marker in patients with sepsis. PloS one\| PubMed ID: 19823581	2009
Non-coding RNAs change their expression profile after Retinoid induced differentiation of the promyelocytic cell line NB4. BMC research notes\| PubMed ID: 20181027	2010
Differential cytogenomics and miRNA signature of the Acute Myeloid Leukaemia Kasumi-1 cell line CD34+38- compartment. Leukemia research\| PubMed ID: 20227111	2010
Modulation of mismatch repair and genomic stability by miR-155. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20351277	2010
Micromarkers: miRNAs in cancer diagnosis and prognosis. Expert review of molecular diagnostics\| PubMed ID: 20370587	2010
Oncogenic role of miR-483-3p at the IGF2/483 locus. Cancer research\| PubMed ID: 20388800	2010
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival. Blood\| PubMed ID: 20393129	2010
Reprogramming of miRNA networks in cancer and leukemia. Genome research\| PubMed ID: 20439436	2010
MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells. Cancer research\| PubMed ID: 20501828	2010
MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia. Molecular cancer\| PubMed ID: 20504344	2010
Altered miRNA expression in T regulatory cells in course of multiple sclerosis. Journal of neuroimmunology\| PubMed ID: 20637509	2010
Clinicobiologic importance of cytogenetic lesions in chronic lymphocytic leukemia. Expert review of hematology\| PubMed ID: 21082972	2009
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. JAMA\| PubMed ID: 21205967	2011
MicroRNAs dysregulation in human malignant pleural mesothelioma. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 21358347	2011
Mutated beta-catenin evades a microRNA-dependent regulatory loop. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21383185	2011
MicroRNA response to environmental mutagens in liver. Mutation research\| PubMed ID: 21514310	2011
microRNA involvement in hepatocellular carcinoma. Anti-cancer agents in medicinal chemistry\| PubMed ID: 21554203	2011
MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin. The Journal of pathology\| PubMed ID: 21630269	2011
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy. The Journal of pathology\| PubMed ID: 21960059	2012
MicroRNAs: toward the clinic for breast cancer patients. Seminars in oncology\| PubMed ID: 22082762	2011
MINT31 methylation in gastric noninvasive neoplasia: potential role in the secondary prevention of gastric cancer. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)\| PubMed ID: 22179688	2012
Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia with "normal" FISH: correlations with clinicobiologic parameters. Blood\| PubMed ID: 22246039	2012
In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2. The Journal of pathology\| PubMed ID: 22262409	2012
Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model. Hepatology (Baltimore, Md.)\| PubMed ID: 22473819	2012
MicroRNA-mediated regulation of pancreatic cancer cell proliferation. Oncology letters\| PubMed ID: 22966344	2010
Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23035210	2012
DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma. Oncotarget\| PubMed ID: 23100393	2012
Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25. Current biology : CB\| PubMed ID: 23246404	2013
BCR/ABL1-positive acute lymphoblastic leukemia relapsing as BCR/ABL1-negative acute lymphoblastic leukemia. Leukemia & lymphoma\| PubMed ID: 23323950	2013
miR-126&126* restored expressions play a tumor suppressor role by directly regulating ADAM9 and MMP7 in melanoma. PloS one\| PubMed ID: 23437250	2013
miR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs. Frontiers in genetics\| PubMed ID: 23630541	2013
CCAT2, a novel non-coding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome research\| PubMed ID: 23796952	2013
STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma. Haematologica\| PubMed ID: 23975180	2014
Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia. BMC medical genomics\| PubMed ID: 24004562	2013
Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24036852	2013
Role of microRNAs in hepatocellular carcinoma: a clinical perspective. OncoTargets and therapy\| PubMed ID: 24039437	2013
First report of circulating microRNAs in tumour necrosis factor receptor-associated periodic syndrome (TRAPS). PloS one\| PubMed ID: 24066048	2013
Anti-tumor activity of a miR-199-dependent oncolytic adenovirus. PloS one\| PubMed ID: 24069256	2013
miR-125b targets erythropoietin and its receptor and their expression correlates with metastatic potential and ERBB2/HER2 expression. Molecular cancer\| PubMed ID: 24165569	2013
p53/mdm2 feedback loop sustains miR-221 expression and dictates the response to anticancer treatments in hepatocellular carcinoma. Molecular cancer research : MCR\| PubMed ID: 24324033	2014
Genetic subclonal complexity and miR125a-5p down-regulation identify a subset of patients with inferior outcome in low-risk CLL patients. Oncotarget\| PubMed ID: 24334759	2014
Modern treatment in chronic lymphocytic leukemia: impact on survival and efficacy in high-risk subgroups. Cancer medicine\| PubMed ID: 24648042	2014
microRNAome expression in chronic lymphocytic leukemia: comparison with normal B-cell subsets and correlations with prognostic and clinical parameters. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24916701	2014
OncomiR detection in circulating body fluids: a PDMS microdevice perspective. Lab on a chip\| PubMed ID: 25178053	2014
Gene expression changes in progression of cervical neoplasia revealed by microarray analysis of cervical neoplastic keratinocytes. Journal of cellular physiology\| PubMed ID: 25205602	2015
Pluripotent stem cell miRNAs and metastasis in invasive breast cancer. Journal of the National Cancer Institute\| PubMed ID: 25306216	2014
Mesenchymal progenitors aging highlights a miR-196 switch targeting HOXB7 as master regulator of proliferation and osteogenesis. Stem cells (Dayton, Ohio)\| PubMed ID: 25428821	2015
Inhibiting the oncogenic mir-221 by microRNA sponge: toward microRNA-based therapeutics for hepatocellular carcinoma. Gastroenterology and hepatology from bed to bench\| PubMed ID: 25436097	2014
Quantification of circulating miRNAs by droplet digital PCR: comparison of EvaGreen- and TaqMan-based chemistries. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 25472671	2014
Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells. PloS one\| PubMed ID: 25849663	2015
Association between gene and miRNA expression profiles and stereotyped subset #4 B-cell receptor in chronic lymphocytic leukemia. Leukemia & lymphoma\| PubMed ID: 25860243	2015
Absolute quantification of cell-free microRNAs in cancer patients. Oncotarget\| PubMed ID: 26036630	2015
miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model. Oncotarget\| PubMed ID: 26090867	2015
Diagnostic and prognostic microRNAs in the serum of breast cancer patients measured by droplet digital PCR. Biomarker research\| PubMed ID: 26120471	2015
Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival. EBioMedicine\| PubMed ID: 26288818	2015
Micromarkers 2.0: an update on the role of microRNAs in cancer diagnosis and prognosis. Expert review of molecular diagnostics\| PubMed ID: 26338209	2015
Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia: Clinical and biologic correlations. Genes, chromosomes & cancer\| PubMed ID: 26355802	2015
Interspecies Gene Name Extrapolation--A New Approach. PloS one\| PubMed ID: 26407293	2015
MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab. Oncotarget\| PubMed ID: 26497852	2015
Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients. BMC cancer\| PubMed ID: 26508446	2015
Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC. PloS one\| PubMed ID: 26509672	2015
MicroRNA profiling of primary pulmonary enteric adenocarcinoma in members from the same family reveals some similarities to pancreatic adenocarcinoma-a step towards personalized therapy. Clinical epigenetics\| PubMed ID: 26677401	2015
miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma. Oncotarget\| PubMed ID: 27057640	2016
Over-expression of the miR-483-3p overcomes the miR-145/TP53 pro-apoptotic loop in hepatocellular carcinoma. Oncotarget\| PubMed ID: 27120784	2016
Dissecting chronic lymphocytic leukemia with 13q- using microRNA expression profile: Editorial for the paper "MiRNA expression profile of chronic lymphocytic leukemia patients with 13q delet... Leukemia research\| PubMed ID: 27304710	2016