Benjamin A. Garcia

Epigenetics Program, University of Pennsylvania

Affiliated withUniversity of Pennsylvania University of Pennsylvania Perelman School of Medicine Washington University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 227	2016
Publication title Cited by 1	2017
Publication title Cited by 7	2024

Other Publications

Article	Year
Improvement in the apparent mass resolution of oligonucleotides by using 12C/14N-enriched samples. Analytical chemistry\| PubMed ID: 11795798	2002
Improvement of the MALDI-TOF analysis of DNA with thin-layer matrix preparation. Analytical chemistry\| PubMed ID: 12033310	2002
Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry. Journal of proteome research\| PubMed ID: 15595731	2004
Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications. Nucleic acids research\| PubMed ID: 15598823	2004
Simian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor. Molecular and cellular biology\| PubMed ID: 15684382	2005
Analysis of protein phosphorylation by mass spectrometry. Methods (San Diego, Calif.)\| PubMed ID: 15722222	2005
Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15851689	2005
Modifications of human histone H3 variants during mitosis. Biochemistry\| PubMed ID: 16185088	2005
The platelet microparticle proteome. Journal of proteome research\| PubMed ID: 16212402	2005
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature\| PubMed ID: 16222246	2005
Expression patterns and post-translational modifications associated with mammalian histone H3 variants. The Journal of biological chemistry\| PubMed ID: 16267050	2006
Resetting the epigenetic histone code in the MRL-lpr/lpr mouse model of lupus by histone deacetylase inhibition. Journal of proteome research\| PubMed ID: 16335948	2005
Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation. The Journal of biological chemistry\| PubMed ID: 16513652	2006
Comprehensive phosphoprotein analysis of linker histone H1 from Tetrahymena thermophila. Molecular & cellular proteomics : MCP\| PubMed ID: 16835217	2006
Site-specific casein kinase 1epsilon-dependent phosphorylation of Dishevelled modulates beta-catenin signaling. The FEBS journal\| PubMed ID: 16965538	2006
Protein profile of osteoarthritic human articular cartilage using tandem mass spectrometry. Rapid communications in mass spectrometry : RCM\| PubMed ID: 16969770	2006
A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes & development\| PubMed ID: 16980585	2006
Characterization of histones and their post-translational modifications by mass spectrometry. Current opinion in chemical biology\| PubMed ID: 17157550	2007
Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. The Journal of biological chemistry\| PubMed ID: 17189264	2007
Organismal differences in post-translational modifications in histones H3 and H4. The Journal of biological chemistry\| PubMed ID: 17194708	2007
Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. The EMBO journal\| PubMed ID: 17318175	2007
Chemical derivatization of histones for facilitated analysis by mass spectrometry. Nature protocols\| PubMed ID: 17446892	2007
Pervasive combinatorial modification of histone H3 in human cells. Nature methods\| PubMed ID: 17529979	2007
Mild performic acid oxidation enhances chromatographic and top down mass spectrometric analyses of histones. Molecular & cellular proteomics : MCP\| PubMed ID: 17569892	2007
Tissue-specific expression and post-translational modification of histone H3 variants. Journal of proteome research\| PubMed ID: 18700791	2008
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell\| PubMed ID: 18957203	2008
Analysis of histones in Xenopus laevis. II. mass spectrometry reveals an index of cell type-specific modifications on H3 and H4. The Journal of biological chemistry\| PubMed ID: 18957437	2009
Tandem mass spectrometry with ultrahigh mass accuracy clarifies peptide identification by database retrieval. Journal of proteome research\| PubMed ID: 19053528	2009
Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance. Molecular and cellular biology\| PubMed ID: 19158276	2009
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular cell\| PubMed ID: 19250903	2009
Mass spectrometric analysis of histone variants and post-translational modifications. Frontiers in bioscience (Scholar edition)\| PubMed ID: 19482690	2009
Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Molecular & cellular proteomics : MCP\| PubMed ID: 19567367	2009
High throughput characterization of combinatorial histone codes. Molecular & cellular proteomics : MCP\| PubMed ID: 19654425	2009
Proteome-wide prediction of acetylation substrates. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19666589	2009
A mixed integer linear optimization framework for the identification and quantification of targeted post-translational modifications of highly modified proteins using multiplexed electron tr... Molecular & cellular proteomics : MCP\| PubMed ID: 19666874	2009
Protein quantification across hundreds of experimental conditions. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19717460	2009
One-pot shotgun quantitative mass spectrometry characterization of histones. Journal of proteome research\| PubMed ID: 19764812	2009
Electron transfer dissociation facilitates sequencing of adenosine diphosphate-ribosylated peptides. Analytical chemistry\| PubMed ID: 19928949	2010
In vivo residue-specific histone methylation dynamics. The Journal of biological chemistry\| PubMed ID: 19940157	2010
What does the future hold for Top Down mass spectrometry? Journal of the American Society for Mass Spectrometry\| PubMed ID: 19942451	2010
A novel approach for untargeted post-translational modification identification using integer linear optimization and tandem mass spectrometry. Molecular & cellular proteomics : MCP\| PubMed ID: 20103568	2010
Modern approaches for investigating epigenetic signaling pathways. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 20110548	2010
Systems-wide proteomic characterization of combinatorial post-translational modification patterns. Expert review of proteomics\| PubMed ID: 20121478	2010
Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nature chemical biology\| PubMed ID: 20190764	2010
Collective mass spectrometry approaches reveal broad and combinatorial modification of high mobility group protein A1a. Journal of the American Society for Mass Spectrometry\| PubMed ID: 20202861	2010
Histone H1 variant-specific lysine methylation by G9a/KMT1C and Glp1/KMT1D. Epigenetics & chromatin\| PubMed ID: 20334638	2010
Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown. Molecular bioSystems\| PubMed ID: 20577673	2010
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature\| PubMed ID: 20622853	2010
The significance, development and progress of high-throughput combinatorial histone code analysis. Cellular and molecular life sciences : CMLS\| PubMed ID: 20683756	2010
Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature\| PubMed ID: 20686576	2010
Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. Epigenetics\| PubMed ID: 21124070	2010
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nature immunology\| PubMed ID: 21131967	2011
Global turnover of histone post-translational modifications and variants in human cells. Epigenetics & chromatin\| PubMed ID: 21134274	2010
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature\| PubMed ID: 21179167	2010
Isoform-specific phosphorylation of human linker histone H1.4 in mitosis by the kinase Aurora B. Journal of cell science\| PubMed ID: 21511733	2011
Revealing histone variant induced changes via quantitative proteomics. Critical reviews in biochemistry and molecular biology\| PubMed ID: 21526979	2011
Proteomics. Journal of biomedicine & biotechnology\| PubMed ID: 21541239	2010
Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity. The Journal of biological chemistry\| PubMed ID: 21708950	2011
The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Molecular cell\| PubMed ID: 21726816	2011
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nature chemical biology\| PubMed ID: 21743462	2011
Methylation of H2AR29 is a novel repressive PRMT6 target. Epigenetics & chromatin\| PubMed ID: 21774791	2011
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature medicine\| PubMed ID: 21822286	2011
Proteomic interrogation of human chromatin. PloS one\| PubMed ID: 21935452	2011
Quantitative proteomic approaches to studying histone modifications. Current chemical genomics\| PubMed ID: 21966350	2011
Breaking the histone code with quantitative mass spectrometry. Expert review of proteomics\| PubMed ID: 21999833	2011
Novel protein identification methods for biomarker discovery via a proteomic analysis of periodontally healthy and diseased gingival crevicular fluid samples. Journal of clinical periodontology\| PubMed ID: 22092770	2012
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Molecular cell\| PubMed ID: 22099308	2011
Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses. Nature structural & molecular biology\| PubMed ID: 22343720	2012
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA. Molecular cell\| PubMed ID: 22387026	2012
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. Genes & development\| PubMed ID: 22391447	2012
Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Epigenetics\| PubMed ID: 22419068	2012
Origins and formation of histone methylation across the human cell cycle. Molecular and cellular biology\| PubMed ID: 22547680	2012
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22615382	2012
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nature medicine\| PubMed ID: 22635005	2012
BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22645331	2012
Global secretome analysis identifies novel mediators of bone metastasis. Cell research\| PubMed ID: 22688892	2012
Discovery of lysine post-translational modifications through mass spectrometric detection. Essays in biochemistry\| PubMed ID: 22708569	2012
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature\| PubMed ID: 22722849	2012
Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies. Scientific reports\| PubMed ID: 22761995	2012
PILOT_PROTEIN: identification of unmodified and modified proteins via high-resolution mass spectrometry and mixed-integer linear optimization. Journal of proteome research\| PubMed ID: 22788846	2012
Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins. Genome biology\| PubMed ID: 22897906	2012
Examining histone posttranslational modification patterns by high-resolution mass spectrometry. Methods in enzymology\| PubMed ID: 22910200	2012
Asymmetrically modified nucleosomes. Cell\| PubMed ID: 23021224	2012
Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. Journal of proteome research\| PubMed ID: 23181431	2012
Discovery of biomarker combinations that predict periodontal health or disease with high accuracy from GCF samples based on high-throughput proteomic analysis and mixed-integer linear optimi... Journal of clinical periodontology\| PubMed ID: 23190455	2012
Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nature structural & molecular biology\| PubMed ID: 23295261	2013
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics\| PubMed ID: 23324626	2013
Comprehending dynamic protein methylation with mass spectrometry. Current opinion in chemical biology\| PubMed ID: 23333572	2013
Validation of protein acetylation by mass spectrometry. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23381849	2013
Heavy methyl-SILAC labeling coupled with liquid chromatography and high-resolution mass spectrometry to study the dynamics of site-specific histone methylation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23436372	2013
Quantitative dynamics of the link between cellular metabolism and histone acetylation. The Journal of biological chemistry\| PubMed ID: 23482559	2013
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (New York, N.Y.)\| PubMed ID: 23539183	2013
Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature\| PubMed ID: 23615611	2013
Large-scale global identification of protein lysine methylation in vivo. Epigenetics\| PubMed ID: 23644510	2013
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nature cell biology\| PubMed ID: 23748610	2013
Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23818587	2013
A quantitative atlas of histone modification signatures from human cancer cells. Epigenetics & chromatin\| PubMed ID: 23826629	2013
Combining genomic and proteomic approaches for epigenetics research. Epigenomics\| PubMed ID: 23895656	2013
Proteomic characterization of novel histone post-translational modifications. Epigenetics & chromatin\| PubMed ID: 23916056	2013
H4K20 methylation regulates quiescence and chromatin compaction. Molecular biology of the cell\| PubMed ID: 23924899	2013
Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics\| PubMed ID: 23949383	2013
H3R42me2a is a histone modification with positive transcriptional effects. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23980157	2013
Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling. Scientific reports\| PubMed ID: 24169447	2013
Identification and interrogation of combinatorial histone modifications. Frontiers in genetics\| PubMed ID: 24391660	2013
Neutron-encoded mass signatures for quantitative top-down proteomics. Analytical chemistry\| PubMed ID: 24475910	2014
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Molecular cell\| PubMed ID: 24486017	2014
Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination. Molecular & cellular proteomics : MCP\| PubMed ID: 24532841	2014
De novo peptide design and experimental validation of histone methyltransferase inhibitors. PloS one\| PubMed ID: 24587223	2014
De novo peptide design and experimental validation of histone methyltransferase inhibitors. PloS one\| PubMed ID: 24740276	2014
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature\| PubMed ID: 24847881	2014
ChIP-less analysis of chromatin states. Epigenetics & chromatin\| PubMed ID: 24872844	2014
Mass spectrometric analysis of histone proteoforms. Annual review of analytical chemistry (Palo Alto, Calif.)\| PubMed ID: 24896311	2014
Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection. Molecular & cellular proteomics : MCP\| PubMed ID: 24987098	2014
Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell metabolism\| PubMed ID: 24998913	2014
Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry. Molecular & cellular proteomics : MCP\| PubMed ID: 25000943	2014
Middle-Down and Top-Down Mass Spectrometric Analysis of Co-occurring Histone Modifications. Current protocols in protein science / editorial board, John E. Coligan ... [et al.]\| PubMed ID: 25081742	2014
A proteomic glimpse into the initial global epigenetic changes during HIV infection. Proteomics\| PubMed ID: 25116026	2014
Histone methylation has dynamics distinct from those of histone acetylation in cell cycle reentry from quiescence. Molecular and cellular biology\| PubMed ID: 25154414	2014
Evaluation of proteomic search engines for the analysis of histone modifications. Journal of proteome research\| PubMed ID: 25167464	2014
SnapShot: histone modifications. Cell\| PubMed ID: 25303536	2014
In vivo proximity labeling for the detection of protein-protein and protein-RNA interactions. Journal of proteome research\| PubMed ID: 25311790	2014
High resolution is not a strict requirement for characterization and quantification of histone post-translational modifications. Journal of proteome research\| PubMed ID: 25325711	2014
Analytical tools and current challenges in the modern era of neuroepigenomics. Nature neuroscience\| PubMed ID: 25349914	2014
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. Nature structural & molecular biology\| PubMed ID: 25383670	2014
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia. Blood\| PubMed ID: 25395428	2015
Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2. Genome research\| PubMed ID: 25467431	2015
Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. Nature cell biology\| PubMed ID: 25503565	2015
The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression. Developmental cell\| PubMed ID: 25625206	2015
Sequential Window Acquisition of all Theoretical Mass Spectra (SWATH) Analysis for Characterization and Quantification of Histone Post-translational Modifications. Molecular & cellular proteomics : MCP\| PubMed ID: 25636311	2015
Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis. Proteomics\| PubMed ID: 25641854	2015
A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation. Molecular cell\| PubMed ID: 25684206	2015
Quantitative proteomic analysis of histone modifications. Chemical reviews\| PubMed ID: 25688442	2015
Characterization of BRD4 during mammalian postmeiotic sperm development. Molecular and cellular biology\| PubMed ID: 25691659	2015
Bottom-up and middle-down proteomics have comparable accuracies in defining histone post-translational modification relative abundance and stoichiometry. Analytical chemistry\| PubMed ID: 25719549	2015
EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra. Molecular & cellular proteomics : MCP\| PubMed ID: 25805797	2015
LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. The Journal of biological chemistry\| PubMed ID: 25825497	2015
Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants. Epigenetics & chromatin\| PubMed ID: 25878728	2015
Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications. Epigenetics & chromatin\| PubMed ID: 25922622	2015
Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression. BMC genomics\| PubMed ID: 26040834	2015
Characterization of histone post-translational modifications during virus infection using mass spectrometry-based proteomics. Methods (San Diego, Calif.)\| PubMed ID: 26093074	2015
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron\| PubMed ID: 26139371	2015
Properly reading the histone code by MS-based proteomics. Proteomics\| PubMed ID: 26223514	2015
Analysis of Histones H3 and H4 Reveals Novel and Conserved Post-Translational Modifications in Sugarcane. PloS one\| PubMed ID: 26226299	2015
Comprehensive Catalog of Currently Documented Histone Modifications. Cold Spring Harbor perspectives in biology\| PubMed ID: 26330523	2015
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Nature medicine\| PubMed ID: 26366710	2015
Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations. Expert review of proteomics\| PubMed ID: 26400466	2015
The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Molecular cell\| PubMed ID: 26439302	2015
Low Resolution Data-Independent Acquisition in an LTQ-Orbitrap Allows for Simplified and Fully Untargeted Analysis of Histone Modifications. Analytical chemistry\| PubMed ID: 26505526	2015
Tumour exosome integrins determine organotropic metastasis. Nature\| PubMed ID: 26524530	2015
Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin. Genome research\| PubMed ID: 26537359	2016
Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications. Cancer research\| PubMed ID: 26542213	2015
Monitoring Cellular Phosphorylation Signaling Pathways into Chromatin and Down to the Gene Level. Molecular & cellular proteomics : MCP\| PubMed ID: 26543102	2016
H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis. Cell reports\| PubMed ID: 26628362	2015
Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation. Proteomics\| PubMed ID: 26631989	2016
Permuting the PGF Signature Motif Blocks both Archaeosortase-Dependent C-Terminal Cleavage and Prenyl Lipid Attachment for the Haloferax volcanii S-Layer Glycoprotein. Journal of bacteriology\| PubMed ID: 26712937	2015
Tet2 Catalyzes Stepwise 5-Methylcytosine Oxidation by an Iterative and de novo Mechanism. Journal of the American Chemical Society\| PubMed ID: 26734843	2016
Quantitative Profiling of the Activity of Protein Lysine Methyltransferase SMYD2 Using SILAC-Based Proteomics. Molecular & cellular proteomics : MCP\| PubMed ID: 26750096	2016
Analyses of Histone Proteoforms Using Front-end Electron Transfer Dissociation-enabled Orbitrap Instruments. Molecular & cellular proteomics : MCP\| PubMed ID: 26785730	2016
Bioorthogonal Chemistry for the Isolation and Study of Newly Synthesized Histones and Their Modifications. ACS chemical biology\| PubMed ID: 26789204	2016
Reshaping the Chromatin and Epigenetic Landscapes with Quantitative Mass Spectrometry. Molecular & cellular proteomics : MCP\| PubMed ID: 26814188	2016
Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells. BMC genomics\| PubMed ID: 26847871	2016
Folate deficiency affects histone methylation. Medical hypotheses\| PubMed ID: 26880641	2016
A novel quantitative mass spectrometry platform for determining protein O-GlcNAcylation dynamics. Molecular & cellular proteomics : MCP\| PubMed ID: 27114449	2016
PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity. Molecular cell\| PubMed ID: 27151440	2016
Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling. Molecular cell\| PubMed ID: 27153536	2016
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science (New York, N.Y.)\| PubMed ID: 27174990	2016
Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 29127121	2018
Human chimeric antigen receptor macrophages for cancer immunotherapy. Nature biotechnology\| PubMed ID: 32361713	2020
Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity. EMBO reports\| PubMed ID: 34347354	2021
Multi-omic profiling of histone variant H3.3 lysine 27 methylation reveals a distinct role from canonical H3 in stem cell differentiation. Molecular omics\| PubMed ID: 35044400	2022
Data-Independent Acquisition for the Detection of Mononucleoside RNA Modifications by Mass Spectrometry. Journal of the American Society for Mass Spectrometry\| PubMed ID: 35357823	2022
H3K36 dimethylation shapes the epigenetic interaction landscape by directing repressive chromatin modifications in embryonic stem cells. Genome research\| PubMed ID: 35396277	2022
Permethylation of Ribonucleosides Provides Enhanced Mass Spectrometry Quantification of Post-Transcriptional RNA Modifications. Analytical chemistry\| PubMed ID: 35549217	2022
Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4). Human molecular genetics\| PubMed ID: 35640156	2022
Nucleome programming is required for the foundation of totipotency in mammalian germline development. The EMBO journal\| PubMed ID: 35703121	2022
Top-"Double-Down" Mass Spectrometry of Histone H4 Proteoforms: Tandem Ultraviolet-Photon and Mobility/Mass-Selected Electron Capture Dissociations. Analytical chemistry\| PubMed ID: 36282112	2022
Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 36322731	2022
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas. Nature genetics\| PubMed ID: 36471070	2022
Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation. Cell reports\| PubMed ID: 36516747	2022
Arginine Methylation of the PGC-1α C-Terminus Is Temperature-Dependent. Biochemistry\| PubMed ID: 36535003	2023
Characterizing crosstalk in epigenetic signaling to understand disease physiology. The Biochemical journal\| PubMed ID: 36630129	2023
Expanding the Epitranscriptomic RNA Sequencing and Modification Mapping Mass Spectrometry Toolbox with Field Asymmetric Waveform Ion Mobility and Electrochemical Elution Liquid Chromatograph... Analytical chemistry\| PubMed ID: 36916610	2023
Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration. Cell\| PubMed ID: 36931244	2023
Alternative splicing of HDAC7 regulates its interaction with 14-3-3 proteins to alter histone marks and target gene expression. Cell reports\| PubMed ID: 36933216	2023
Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors. bioRxiv : the preprint server for biology\| PubMed ID: 37292747	2023
A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy. Journal of medicinal chemistry\| PubMed ID: 37651366	2023
Acetyl-methyllysine marks chromatin at active transcription start sites. Nature\| PubMed ID: 37731000	2023
Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors. ACS chemical biology\| PubMed ID: 37737090	2023
SWAMNA: a comprehensive platform for analysis of nucleic acid modifications. Chemical communications (Cambridge, England)\| PubMed ID: 37786919	2023
Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation. bioRxiv : the preprint server for biology\| PubMed ID: 37808786	2023
An Optimized and High-Throughput Method for Histone Propionylation and Data-Independent Acquisition Analysis for the Identification and Quantification of Histone Post-translational Modificat... Journal of the American Society for Mass Spectrometry\| PubMed ID: 37853520	2023
The antiproliferative effect of FGF2 in K-Ras-driven tumor cells involves modulation of rRNA and the nucleolus. Journal of cell science\| PubMed ID: 37921359	2023
Electrostatic encoding of genome organization principles within single native nucleosomes. bioRxiv : the preprint server for biology\| PubMed ID: 38106048	2023
Phosphorylation regulates viral biomolecular condensates to promote infectious progeny production. The EMBO journal\| PubMed ID: 38177504	2024