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Journal
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Chemistry
/
Histone Proteomic Analysis and Post-Translational Modification Characterization
/
Author Spotlight: Enhanced Histone PTM Isomer Identification Through LC-TIMS-ToF MS/MS and PASEF
JoVE Journal
Chemistry
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JoVE Journal
Chemistry
Histone Modification Screening using Liquid Chromatography, Trapped Ion Mobility Spectrometry, and Time-Of-Flight Mass Spectrometry
Author Spotlight: Enhanced Histone PTM Isomer Identification Through LC-TIMS-ToF MS/MS and PASEF
Histone Proteomic Analysis and Post-Translational Modification Characterization
DOI:
10.3791/65589-v
•
01:32 min
•
January 12, 2024
•
Meiby Fernandez-Rojas
,
Cassandra N. Fuller
,
Lilian Valadares Tose
,
Matthew Willetts
,
Melvin A. Park
,
Natarajan V. Bhanu
,
Benjamin A. Garcia
,
Francisco Fernandez-Lima
4
1
Department of Chemistry and Biochemistry
,
Florida International University
,
2
Bruker Daltonics Inc.
,
3
Department of Biochemistry and Molecular Biophysics
,
Washington University School of Medicine
,
4
Biomolecular Sciences Institute
,
Florida International University
Tags
Keywords: Histone Modification
Liquid Chromatography
Trapped Ion Mobility Spectrometry
Time-of-flight Mass Spectrometry
Post-translational Modifications
Epigenetics
Proteomics
Bioinformatics
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Author Spotlight: Enhanced Histone PTM Isomer Identification Through LC-TIMS-ToF MS/MS and PASEF
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