Jean-Pierre Gorvel

Centre d’Immunologie de Marseille-Luminy, Université de la Méditérannée UM2, INSERM U1104 CNRS UM7280

Affiliated withUniversité de la Méditérannée UM2, INSERM U1104 CNRS UM7280

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2016

Other Publications

Article	Year
Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking. Cellular microbiology\| PubMed ID: 12366403	2002
Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification. Infection and immunity\| PubMed ID: 11854238	2002
The cytoplasmic tail of invariant chain regulates endosome fusion and morphology. Molecular biology of the cell\| PubMed ID: 12058053	2002
Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12370385	2002
Brucella intracellular life: from invasion to intracellular replication. Veterinary microbiology\| PubMed ID: 12414149	2002
Salmonella typhimurium SifA effector protein requires its membrane-anchoring C-terminal hexapeptide for its biological function. The Journal of biological chemistry\| PubMed ID: 12574170	2003
Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. The EMBO journal\| PubMed ID: 12660152	2003
Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum. The Journal of experimental medicine\| PubMed ID: 12925673	2003
Organelle robbery: Brucella interactions with the endoplasmic reticulum. Current opinion in microbiology\| PubMed ID: 15036147	2004
Intracellular trafficking study of a RB51 B. abortus vaccinal strain isolated from cow milk. Veterinary microbiology\| PubMed ID: 15036539	2004
Improved methods for producing outer membrane vesicles in Gram-negative bacteria. Research in microbiology\| PubMed ID: 15249060	2004
Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15294184	2004
Link between impaired maturation of phagosomes and defective Coxiella burnetii killing in patients with chronic Q fever. The Journal of infectious diseases\| PubMed ID: 15499532	2004
Brucella coopts the small GTPase Sar1 for intracellular replication. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15632218	2005
Bacteria spurned by self-absorbed cells. Nature medicine\| PubMed ID: 15635436	2005
Brucella lipopolysaccharide acts as a virulence factor. Current opinion in microbiology\| PubMed ID: 15694858	2005
Intracellular trafficking of Parachlamydia acanthamoebae. Cellular microbiology\| PubMed ID: 15760458	2005
Bactericidal and antiendotoxic properties of short cationic peptides derived from a snake venom Lys49 phospholipase A2. Antimicrobial agents and chemotherapy\| PubMed ID: 15793109	2005
Proteome analysis of Rickettsia conorii by two-dimensional gel electrophoresis coupled with mass spectrometry. FEMS microbiology letters\| PubMed ID: 15837377	2005
Cyclic beta-1,2-glucan is a Brucella virulence factor required for intracellular survival. Nature immunology\| PubMed ID: 15880113	2005
Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region. Toxicon : official journal of the International Society on Toxinology\| PubMed ID: 15904676	2005
The intracellular fate of Salmonella depends on the recruitment of kinesin. Science (New York, N.Y.)\| PubMed ID: 15905402	2005
Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol. Molecular microbiology\| PubMed ID: 16091048	2005
Molecular motors hijacking by intracellular pathogens. Cellular microbiology\| PubMed ID: 16367863	2006
Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts. Cellular microbiology\| PubMed ID: 16441431	2006
Differential inductions of TNF-alpha and IGTP, IIGP by structurally diverse classic and non-classic lipopolysaccharides. Cellular microbiology\| PubMed ID: 16469053	2006
Rickettsia conorii and R. prowazekii proteome analysis by 2DE-MS: a step toward functional analysis of rickettsial genomes. Annals of the New York Academy of Sciences\| PubMed ID: 16481497	2005
Pathogen-endoplasmic-reticulum interactions: in through the out door. Nature reviews. Immunology\| PubMed ID: 16491138	2006
Identification of two putative rickettsial adhesins by proteomic analysis. Research in microbiology\| PubMed ID: 16574381	2006
Synthesis of phosphatidylcholine, a typical eukaryotic phospholipid, is necessary for full virulence of the intracellular bacterial parasite Brucella abortus. Cellular microbiology\| PubMed ID: 16882035	2006
The Salmonella effector protein PipB2 is a linker for kinesin-1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16938850	2006
Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products. Journal of virology\| PubMed ID: 16971431	2006
The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche. Infection and immunity\| PubMed ID: 17015457	2006
Microbiology. Bacterial bushwacking through a microtubule jungle. Science (New York, N.Y.)\| PubMed ID: 17095683	2006
Proteome analysis of Rickettsia felis highlights the expression profile of intracellular bacteria. Proteomics\| PubMed ID: 17385819	2007
Virulence factors in brucellosis: implications for aetiopathogenesis and treatment. Expert reviews in molecular medicine\| PubMed ID: 18088444	2007
Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1. PLoS pathogens\| PubMed ID: 18266466	2008
Nanobacteria are mineralo fetuin complexes. PLoS pathogens\| PubMed ID: 18282102	2008
Analysis of kinesin accumulation on Salmonella-containing vacuoles. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18363240	2007
Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export. PloS one\| PubMed ID: 18648644	2008
Brucella: a Mr "Hide" converted into Dr Jekyll. Microbes and infection / Institut Pasteur\| PubMed ID: 18664389	2008
Is Brucella an enteric pathogen? Nature reviews. Microbiology\| PubMed ID: 19172149	2009
The differential interaction of Brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens. PloS one\| PubMed ID: 19529776	2009
The glyceraldehyde-3-phosphate dehydrogenase and the small GTPase Rab 2 are crucial for Brucella replication. PLoS pathogens\| PubMed ID: 19557163	2009
Brucella abortus induces Irgm3 and Irga6 expression via type-I IFN by a MyD88-dependent pathway, without the requirement of TLR2, TLR4, TLR5 and TLR9. Microbial pathogenesis\| PubMed ID: 19747534	2009
Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme. Gastroenterology\| PubMed ID: 19800337	2010
Interaction between the SifA virulence factor and its host target SKIP is essential for Salmonella pathogenesis. The Journal of biological chemistry\| PubMed ID: 19801640	2009
Bacterial manipulation of innate immunity to promote infection. Nature reviews. Microbiology\| PubMed ID: 20075926	2010
The Brucella abortus phosphoglycerate kinase mutant is highly attenuated and induces protection superior to that of vaccine strain 19 in immunocompromised and immunocompetent mice. Infection and immunity\| PubMed ID: 20194591	2010
SKIP, the host target of the Salmonella virulence factor SifA, promotes kinesin-1-dependent vacuolar membrane exchanges. Traffic (Copenhagen, Denmark)\| PubMed ID: 20406420	2010
Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system. PloS one\| PubMed ID: 20422049	2010
Helicobacter pylori impairs murine dendritic cell responses to infection. PloS one\| PubMed ID: 20523725	2010
Inactivation of formyltransferase (wbkC) gene generates a Brucella abortus rough strain that is attenuated in macrophages and in mice. Vaccine\| PubMed ID: 20580469	2010
The virulence protein SopD2 regulates membrane dynamics of Salmonella-containing vacuoles. PLoS pathogens\| PubMed ID: 20664790	2010
Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection. European journal of immunology\| PubMed ID: 21108467	2010
Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern. PloS one\| PubMed ID: 21249206	2011
An evolutionary strategy for a stealthy intracellular Brucella pathogen. Immunological reviews\| PubMed ID: 21349096	2011
Salmonella detoxifying enzymes are sufficient to cope with the host oxidative burst. Molecular microbiology\| PubMed ID: 21362067	2011
Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2. Cellular microbiology\| PubMed ID: 21501366	2011
In search of Brucella abortus type IV secretion substrates: screening and identification of four proteins translocated into host cells through VirB system. Cellular microbiology\| PubMed ID: 21707904	2011
Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores. Gastroenterology\| PubMed ID: 22155637	2012
Internal affairs: investigating the Brucella intracellular lifestyle. FEMS microbiology reviews\| PubMed ID: 22373010	2012
What have we learned from brucellosis in the mouse model? Veterinary research\| PubMed ID: 22500859	2012
The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming. Blood\| PubMed ID: 22535664	2012
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition. PLoS pathogens\| PubMed ID: 22589715	2012
Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells. PLoS pathogens\| PubMed ID: 23166489	2012
Small GTPases and Brucella entry into the endoplasmic reticulum. Biochemical Society transactions\| PubMed ID: 23176479	2012
Lipopolysaccharide as a target for brucellosis vaccine design. Microbial pathogenesis\| PubMed ID: 23219811	2013
Pathogenic brucellae replicate in human trophoblasts. The Journal of infectious diseases\| PubMed ID: 23303808	2013
Brucella T4SS: the VIP pass inside host cells. Current opinion in microbiology\| PubMed ID: 23318140	2013
Brucella evasion of adaptive immunity. Future microbiology\| PubMed ID: 23374122	2013
Lipopolysaccharides with acylation defects potentiate TLR4 signaling and shape T cell responses. PloS one\| PubMed ID: 23390517	2013
Neutrophils exert a suppressive effect on Th1 responses to intracellular pathogen Brucella abortus. PLoS pathogens\| PubMed ID: 23458832	2013
BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions. Frontiers in cellular and infection microbiology\| PubMed ID: 23847770	2013
Bartonella and Brucella--weapons and strategies for stealth attack. Cold Spring Harbor perspectives in medicine\| PubMed ID: 23906880	2013
Human plasma cells express granzyme B. European journal of immunology\| PubMed ID: 24114594	2014
In vivo identification and characterization of CD4⁺ cytotoxic T cells induced by virulent Brucella abortus infection. PloS one\| PubMed ID: 24367519	2013
A toxin-antitoxin module of Salmonella promotes virulence in mice. PLoS pathogens\| PubMed ID: 24385907	2013
"If you bring an alarm, we will destroy it," said Brucella to the host cell. Virulence\| PubMed ID: 24786767	2014
Intracellular bacteria interfere with dendritic cell functions: role of the type I interferon pathway. PloS one\| PubMed ID: 24915541	2014
Myeloid decidual dendritic cells and immunoregulation of pregnancy: defective responsiveness to Coxiella burnetii and Brucella abortus. Frontiers in cellular and infection microbiology\| PubMed ID: 25566514	2014
Brucella CβG induces a dual pro- and anti-inflammatory response leading to a transient neutrophil recruitment. Virulence\| PubMed ID: 25654761	2015
Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia. PLoS pathogens\| PubMed ID: 25781937	2015
Cervical Lymph Nodes as a Selective Niche for Brucella during Oral Infections. PloS one\| PubMed ID: 25919005	2014
Innate and adaptive immune functions of peyer's patch monocyte-derived cells. Cell reports\| PubMed ID: 25921539	2015
Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide. PLoS pathogens\| PubMed ID: 25946018	2015
The Salmonella effector protein SifA plays a dual role in virulence. Scientific reports\| PubMed ID: 26268777	2015
RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4. The Journal of cell biology\| PubMed ID: 26416964	2015
Subversion of mouse dendritic cell subset function by bacterial pathogens. Microbial pathogenesis\| PubMed ID: 26453826	2015
Gene expression profiling of the Peyer's patch mononuclear phagocyte system. Genomics data\| PubMed ID: 26484215	2015
Brucella discriminates between mouse dendritic cell subsets upon in vitro infection. Virulence\| PubMed ID: 26606688	2016
Structural Studies of Lipopolysaccharide-defective Mutants from Brucella melitensis Identify a Core Oligosaccharide Critical in Virulence. The Journal of biological chemistry\| PubMed ID: 26867577	2016
Effector proteins support the asymmetric apportioning of Salmonella during cytokinesis. Virulence\| PubMed ID: 27046257	2016
Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8(+) and CD4(+) T Cells. EBioMedicine\| PubMed ID: 27077111	2016