Xiaolu Yang

Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine

Affiliated withUniversity of Pennsylvania Perelman School of Medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2016

Other Publications

Article	Year
c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. The EMBO journal\| PubMed ID: 12110583	2002
The FLIP side of cancer cell death. Cancer biology & therapy\| PubMed ID: 12432256	2002
Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. The Journal of biological chemistry\| PubMed ID: 12525502	2003
DEDD and DEDD2 associate with caspase-8/10 and signal cell death. Oncogene\| PubMed ID: 12527898	2003
Activation of procaspases by FK506 binding protein-mediated oligomerization. Science's STKE : signal transduction knowledge environment\| PubMed ID: 12554853	2003
Oligomerization is a general mechanism for the activation of apoptosis initiator and inflammatory procaspases. The Journal of biological chemistry\| PubMed ID: 12637514	2003
Interdimer processing mechanism of procaspase-8 activation. The EMBO journal\| PubMed ID: 12912912	2003
A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein. The Journal of biological chemistry\| PubMed ID: 14990586	2004
Interdimer processing and linearity of procaspase-3 activation. A unifying mechanism for the activation of initiator and effector caspases. The Journal of biological chemistry\| PubMed ID: 15664982	2005
The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62. FEBS letters\| PubMed ID: 15878163	2005
Association of caspase-2 with the promyelocytic leukemia protein nuclear bodies. Cancer biology & therapy\| PubMed ID: 15917662	2005
Lymphocyte life and death: the caspase-8 connection. Cancer biology & therapy\| PubMed ID: 16082181	2005
cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas. The Journal of clinical investigation\| PubMed ID: 16395405	2006
CIAP2 inhibits anigen receptor signaling by targeting Bcl10 for degredation. Cell cycle (Georgetown, Tex.)\| PubMed ID: 16775419	2006
A novel fusion of the MALT1 gene and the microtubule-associated protein 4 (MAP4) gene occurs in diffuse large B-cell lymphoma. Genes, chromosomes & cancer\| PubMed ID: 16804917	2006
Critical role for Daxx in regulating Mdm2. Nature cell biology\| PubMed ID: 16845383	2006
Lys63-linked polyubiquitin chains: linking more than just ubiquitin. Cancer biology & therapy\| PubMed ID: 16969079	2006
TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. Cell\| PubMed ID: 18455983	2008
Ubiquitination mediated by inhibitor of apoptosis proteins. Methods in enzymology\| PubMed ID: 18603125	2008
The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation. Molecular cell\| PubMed ID: 18691973	2008
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nature immunology\| PubMed ID: 18997794	2008
Inhibition of JAK2/STAT3-mediated VEGF upregulation under high glucose conditions by PEDF through a mitochondrial ROS pathway in vitro. Investigative ophthalmology & visual science\| PubMed ID: 19696171	2010
Distinct MHC gene expression patterns during progression of melanoma. Genes, chromosomes & cancer\| PubMed ID: 19862823	2010
Daxx is reciprocally regulated by Mdm2 and Hausp. Biochemical and biophysical research communications\| PubMed ID: 20153724	2010
tRNA binds to cytochrome c and inhibits caspase activation. Molecular cell\| PubMed ID: 20227371	2010
tRNA and cytochrome c in cell death and beyond. Cell cycle (Georgetown, Tex.)\| PubMed ID: 20676046	2010
Apoptotic regulation and tRNA. Protein & cell\| PubMed ID: 21113408	2010
[Study on effect of total saponins from Semen Nigellae on inflammatory mediators and ERK/MAPK pathway in stimulated macrophage]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 21174772	2010
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase. Nature cell biology\| PubMed ID: 21336310	2011
Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21768358	2011
The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2. The Journal of biological chemistry\| PubMed ID: 21849505	2011
Effects of a novel peptide derived from human thrombomodulin on endotoxin-induced uveitis in vitro and in vivo. FEBS letters\| PubMed ID: 22001200	2011
[Mitochondrial dysfunction induced by excessive ROS/RNS-metabolic cardiovascular disease and traditional Chinese medicines intervention]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 22121816	2011
Chemical composition of volatile oil from Artemisia ordosica and its allelopathic effects on desert soil microalgae, Palmellococcus miniatus. Plant physiology and biochemistry : PPB / Société française de physiologie végétale\| PubMed ID: 22153252	2012
Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22158899	2011
A novel peptide derived from human pancreatitis-associated protein inhibits inflammation in vivo and in vitro and blocks NF-kappa B signaling pathway. PloS one\| PubMed ID: 22195011	2011
A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma. Cancer discovery\| PubMed ID: 22585859	2012
Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells. Cancer biology & therapy\| PubMed ID: 22895069	2012
Gd complexes of diethylenetriaminepentaacetic acid conjugates of low-molecular-weight chitosan oligosaccharide as a new liver-specific MRI contrast agent. Magnetic resonance imaging\| PubMed ID: 23102519	2013
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence. Nature\| PubMed ID: 23334421	2013
Regulation of cell death by transfer RNA. Antioxidants & redox signaling\| PubMed ID: 23350625	2013
Effects of a thrombomodulin-derived peptide on monocyte adhesion and intercellular adhesion molecule-1 expression in lipopolysaccharide-induced endothelial cells. Molecular vision\| PubMed ID: 23401649	2013
Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation. PloS one\| PubMed ID: 23405218	2013
Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity. The Journal of biological chemistry\| PubMed ID: 23671280	2013
TAp73 enhances the pentose phosphate pathway and supports cell proliferation. Nature cell biology\| PubMed ID: 23811687	2013
A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation. Cell cycle (Georgetown, Tex.)\| PubMed ID: 24270845	2013
p53 and regulation of tumor metabolism. Journal of carcinogenesis\| PubMed ID: 24379735	2013
Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells. Cell cycle (Georgetown, Tex.)\| PubMed ID: 24552816	2014
MicroRNA-93 inhibits inflammatory cytokine production in LPS-stimulated murine macrophages by targeting IRAK4. FEBS letters\| PubMed ID: 24642374	2014
Stabilized human TRIM5α protects human T cells from HIV-1 infection. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 24662946	2014
A cellular system that degrades misfolded proteins and protects against neurodegeneration. Molecular cell\| PubMed ID: 24882209	2014
Olive leaf extract inhibits lead poisoning-induced brain injury. Neural regeneration research\| PubMed ID: 25206510	2013
Peptidyl-prolyl isomerization targets rice Aux/IAAs for proteasomal degradation during auxin signalling. Nature communications\| PubMed ID: 26096057	2015
PAPep, a small peptide derived from human pancreatitis-associated protein, attenuates corneal inflammation in vivo and in vitro through the IKKα/β/IκBα/NF-κB signaling pathway. Pharmacological research\| PubMed ID: 26388492	2015
Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. The Journal of biological chemistry\| PubMed ID: 26961879	2016
Isolation and evaluation of endophytic Streptomyces endus OsiSh-2 with potential application for biocontrol of rice blast disease. Journal of the science of food and agriculture\| PubMed ID: 27293085	2016
Two SNAP-25 genetic variants in the binding site of multiple microRNAs and susceptibility of ADHD: A meta-analysis. Journal of psychiatric research\| PubMed ID: 27380186	2016