Ihor R. Lemischka

Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai

Affiliated withIcahn School of Medicine at Mount Sinai Icahn School of Medicine at Mount Sinai

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2016

Other Publications

Article	Year
Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 21563278	2011
Cells for repair: breakout session summary. Annals of the New York Academy of Sciences\| PubMed ID: 12081862	2002
A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. Blood\| PubMed ID: 12200366	2002
A molecular profile of a hematopoietic stem cell niche. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12226475	2002
A stem cell molecular signature. Science (New York, N.Y.)\| PubMed ID: 12228721	2002
Stem cells: interactive niches. Nature\| PubMed ID: 14574394	2003
"Tie-ing" down the hematopoietic niche. Cell\| PubMed ID: 15260982	2004
Stem cell biology: a view toward the future. Annals of the New York Academy of Sciences\| PubMed ID: 15958706	2005
Diversification of stem cell molecular repertoire by alternative splicing. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16183747	2005
Alternative splicing increases complexity of stem cell transcriptome. Cell cycle (Georgetown, Tex.)\| PubMed ID: 16479168	2006
Stem cells and their niches. Science (New York, N.Y.)\| PubMed ID: 16574858	2006
Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16621925	2006
Delivery of short hairpin RNAs--triggers of gene silencing--into mouse embryonic stem cells. Nature methods\| PubMed ID: 16628211	2006
The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells. Nature neuroscience\| PubMed ID: 16680166	2006
Dissecting self-renewal in stem cells with RNA interference. Nature\| PubMed ID: 16767105	2006
shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. Cell stem cell\| PubMed ID: 18371338	2007
A genomewide functional network for the laboratory mouse. PLoS computational biology\| PubMed ID: 18818725	2008
Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell stem cell\| PubMed ID: 19265656	2009
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes & development\| PubMed ID: 19270157	2009
Systems biology of stem cell fate and cellular reprogramming. Nature reviews. Molecular cell biology\| PubMed ID: 19738627	2009
Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 19785031	2009
Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2. Mechanisms of development\| PubMed ID: 19825414	2010
GATE: software for the analysis and visualization of high-dimensional time series expression data. Bioinformatics (Oxford, England)\| PubMed ID: 19892805	2010
Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature\| PubMed ID: 19924215	2009
Hooking up with Oct4. Cell stem cell\| PubMed ID: 20362529	2010
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature\| PubMed ID: 20535210	2010
Exploration of self-renewal and pluripotency in ES cells using RNAi. Methods in enzymology\| PubMed ID: 20699150	2010
Toward a complete in silico, multi-layered embryonic stem cell regulatory network. Wiley interdisciplinary reviews. Systems biology and medicine\| PubMed ID: 20890967	2010
SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells. BMC systems biology\| PubMed ID: 21176149	2010
Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells. PLoS computational biology\| PubMed ID: 21187909	2010
Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21252303	2011
Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood\| PubMed ID: 21343612	2011
Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nature biotechnology\| PubMed ID: 21358635	2011
Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders. Current opinion in cardiology\| PubMed ID: 21451408	2011
Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell\| PubMed ID: 21477851	2011
Stem cells and reprogramming: breaking the epigenetic barrier? Trends in pharmacological sciences\| PubMed ID: 21621281	2011
Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells. Blood\| PubMed ID: 21652676	2011
KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer cell\| PubMed ID: 22264792	2012
Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency. Nature protocols\| PubMed ID: 22441292	2012
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell stem cell\| PubMed ID: 22862944	2012
Reprogramming cell fates: insights from combinatorial approaches. Annals of the New York Academy of Sciences\| PubMed ID: 22901251	2012
Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22988117	2012
Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity. Nature cell biology\| PubMed ID: 23103910	2012
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics\| PubMed ID: 23324626	2013
Induction of a hemogenic program in mouse fibroblasts. Cell stem cell\| PubMed ID: 23770078	2013
ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells. Database : the journal of biological databases and curation\| PubMed ID: 23794736	2013
Patterning pluripotency in embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 23843329	2013
Statistical mechanics of pluripotency. Cell\| PubMed ID: 23911316	2013
Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem cells (Dayton, Ohio)\| PubMed ID: 24022884	2014
Epigenetic roles of MLL oncoproteins are dependent on NF-κB. Cancer cell\| PubMed ID: 24054986	2013
"There will be blood" from fibroblasts. Cell cycle (Georgetown, Tex.)\| PubMed ID: 24335410	2014
'From blood to blood': de-differentiation of hematopoietic progenitors to stem cells. The EMBO journal\| PubMed ID: 24907133	2014
Genomic editing tools to model human diseases with isogenic pluripotent stem cells. Stem cells and development\| PubMed ID: 25075441	2014
Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells. PLoS computational biology\| PubMed ID: 25122140	2014
A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming. Molecular cell\| PubMed ID: 25240402	2014
NetExplore: a web server for modeling small network motifs. Bioinformatics (Oxford, England)\| PubMed ID: 25637559	2015
Modeling familial cancer with induced pluripotent stem cells. Cell\| PubMed ID: 25860607	2015
Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming. Cell stem cell\| PubMed ID: 25936917	2015
Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm. Stem cell reports\| PubMed ID: 26095607	2015
Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen. BMC bioinformatics\| PubMed ID: 26198214	2015
Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal. Stem cell reports\| PubMed ID: 26267829	2015
Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia. Cell reports\| PubMed ID: 26456833	2015
Making a Hematopoietic Stem Cell. Trends in cell biology\| PubMed ID: 26526106	2016
Converting cell fates: generating hematopoietic stem cells de novo via transcription factor reprogramming. Annals of the New York Academy of Sciences\| PubMed ID: 26748878	2016
Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells. Developmental cell\| PubMed ID: 26954547	2016
Emerging Modeling Concepts and Solutions in Stem Cell Research. Current topics in developmental biology\| PubMed ID: 26970649	2016
A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nature communications\| PubMed ID: 27230261	2016
Modeling Cancer with Pluripotent Stem Cells. Trends in cancer\| PubMed ID: 27722205	2016