Paul A. Slesinger

Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies

Affiliated withSalk Institute for Biological Studies The Salk Institute for Biological Studies Icahn School of Medicine at Mount Sinai

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 4	2010
Publication title Cited by 17	2011
Publication title Cited by 17	2016

Other Publications

Article	Year
Evidence for a centrally located gate in the pore of a serotonin-gated ion channel. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11880493	2002
betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation. The Journal of physiology\| PubMed ID: 14724209	2004
Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system. Nature neuroscience\| PubMed ID: 14745451	2004
Minimal structural rearrangement of the cytoplasmic pore during activation of the 5-HT3A receptor. The Journal of biological chemistry\| PubMed ID: 15131114	2004
Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex. Molecular and cellular neurosciences\| PubMed ID: 15691717	2005
Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification. Nature neuroscience\| PubMed ID: 15723059	2005
Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells. PflÃ¼gers Archiv : European journal of physiology\| PubMed ID: 15806402	2005
Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1. Biochemistry\| PubMed ID: 16834334	2006
Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins. The Journal of physiology\| PubMed ID: 17185339	2007
NMR studies of interactions between C-terminal tail of Kir2.1 channel and PDZ1,2 domains of PSD95. Biochemistry\| PubMed ID: 17437338	2007
Coregulation of natively expressed pertussis toxin-sensitive muscarinic receptors with G-protein-activated potassium channels. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17567799	2007
Genetically encoding unnatural amino acids for cellular and neuronal studies. Nature neuroscience\| PubMed ID: 17603477	2007
The role of the cytoplasmic pore in inward rectification of Kir2.1 channels. The Journal of general physiology\| PubMed ID: 17635958	2007
A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction. Nature neuroscience\| PubMed ID: 17828261	2007
RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area. Nature neuroscience\| PubMed ID: 17965710	2007
Subunit-specific regulation of Kir3 channels by sorting nexin 27. Channels (Austin, Tex.)\| PubMed ID: 18690037	2007
Addictive drugs modulate GIRK-channel signaling by regulating RGS proteins. Trends in pharmacological sciences\| PubMed ID: 18790542	2008
Regulation of Kir2.1 channels by the Rho-GTPase, Rac1. Journal of cellular physiology\| PubMed ID: 18932198	2009
A discrete alcohol pocket involved in GIRK channel activation. Nature neuroscience\| PubMed ID: 19561601	2009
Direct interaction of GABAB receptors with M2 muscarinic receptors enhances muscarinic signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20016095	2009
Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. Nature reviews. Neuroscience\| PubMed ID: 20389305	2010
GABAB receptor coupling to G-proteins and ion channels. Advances in pharmacology (San Diego, Calif.)\| PubMed ID: 20655481	2010
Basal GABA regulates GABA(B)R conformation and release probability at single hippocampal synapses. Neuron\| PubMed ID: 20670833	2010
Probing novel GPCR interactions using a combination of FRET and TIRF. Communicative & integrative biology\| PubMed ID: 20798821	2010
Morphine- and CaMKII-dependent enhancement of GIRK channel signaling in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20926668	2010
Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21422294	2011
Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution. Alcoholism, clinical and experimental research\| PubMed ID: 21676006	2011
Compartmentalization of the GABAB receptor signaling complex is required for presynaptic inhibition at hippocampal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21880914	2011