Alessandro Sacchetti

Department of Chemistry, Politecnico di Milano

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 17	2016

Other Publications

Article	Year
trans-6-Aminocyclohept-3-enols, a new designed polyfunctionalized chiral building block for the asymmetric synthesis of 2-substituted-4-hydroxypiperidines. Organic letters\| PubMed ID: 11950364	2002
Total enantioselective synthesis of (-)-cytisine. Organic letters\| PubMed ID: 14961606	2004
Combinatorial solid-phase synthesis of 6-hydroxy-1,2,3,4-tetrahydro-beta-carbolines from l-5-hydroxytryptophan. Journal of combinatorial chemistry\| PubMed ID: 15877474	2005
Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction. The Journal of organic chemistry\| PubMed ID: 16555841	2006
An efficient enantioselective approach to cyclic beta-amino acid derivatives via olefin metathesis reactions. The Journal of organic chemistry\| PubMed ID: 16599640	2006
Microwave-assisted, solid-phase synthesis of a chiral 1,2,3,4-tetrahydro-quinoline library. Combinatorial chemistry & high throughput screening\| PubMed ID: 17100574	2006
Pyrroloisoquinoline-based tetrapeptide analogues mimicking reverse-turn secondary structures. The Journal of organic chemistry\| PubMed ID: 17990894	2007
Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III. Bioorganic & medicinal chemistry\| PubMed ID: 18468444	2008
Olefin metathesis based approach to diversely functionalized pyrrolizidines and indolizidines; total synthesis of (+)-monomorine. The Journal of organic chemistry\| PubMed ID: 19067565	2009
Grignard addition to imines derived from isatine: a method for the asymmetric synthesis of quaternary 3-aminooxindoles. The Journal of organic chemistry\| PubMed ID: 19438187	2009
Tetrahydroisoquinoline-based spirocyclic lactam as a type II' beta-turn inducing peptide mimetic. The Journal of organic chemistry\| PubMed ID: 19785471	2009
Phe-Ala-based diazaspirocyclic lactam as nucleator of type II' β-turn. The Journal of organic chemistry\| PubMed ID: 21222472	2011
Addition of TMSCN to chiral ketimines derived from isatin. Synthesis of an oxindole-based peptidomimetic and a bioactive spirohydantoin. Organic & biomolecular chemistry\| PubMed ID: 21687843	2011
Productivity enhancement of C=C bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes. Chemical communications (Cambridge, England)\| PubMed ID: 22069084	2012
Ugi 4-CR/Pictet-Spengler reaction as a short route to tryptophan-derived peptidomimetics. Organic & biomolecular chemistry\| PubMed ID: 23073566	2012
Synthesis, pharmacological evaluation and conformational investigation of endomorphin-2 hybrid analogues. Molecular diversity\| PubMed ID: 23124951	2013
The diketopiperazine-fused tetrahydro-β-carboline scaffold as a model peptidomimetic with an unusual α-turn secondary structure. Beilstein journal of organic chemistry\| PubMed ID: 23399789	2013
Tetrahydro-β-carboline-based spirocyclic lactam as type II' β-turn: application to the synthesis and biological evaluation of somatostatine mimetics. The Journal of organic chemistry\| PubMed ID: 23409740	2013
Substrate scope and synthetic applications of the enantioselective reduction of α-alkyl-β-arylenones mediated by Old Yellow Enzymes. Organic & biomolecular chemistry\| PubMed ID: 23532545	2013
Synthesis of robalzotan, ebalzotan, and rotigotine precursors via the stereoselective multienzymatic cascade reduction of α,β-unsaturated aldehydes. The Journal of organic chemistry\| PubMed ID: 23611252	2013
Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels. British journal of pharmacology\| PubMed ID: 23902373	2014
Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins. Bioorganic & medicinal chemistry\| PubMed ID: 24103429	2013
Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation. Molecular diversity\| PubMed ID: 24500310	2014
Structural and biological exploration of phe(3)-phe(4)-modified endomorphin-2 peptidomimetics. ACS medicinal chemistry letters\| PubMed ID: 24900748	2013
Asymmetric Ugi 3CR on isatin-derived ketimine: synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives. Beilstein journal of organic chemistry\| PubMed ID: 24991292	2014
Multicomponent Synthesis and Biological Evaluation of a Piperazine-Based Dopamine Receptor Ligand Library. ACS medicinal chemistry letters\| PubMed ID: 26288260	2015
Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analogues. Organic & biomolecular chemistry\| PubMed ID: 26467486	2015
A new three dimensional biomimetic hydrogel to deliver factors secreted by human mesenchymal stem cells in spinal cord injury. Biomaterials\| PubMed ID: 26497428	2016
Organocatalytic Asymmetric Biginelli-like Reaction Involving Isatin. The Journal of organic chemistry\| PubMed ID: 26836474	2016
Tunable drug delivery using chemoselective functionalization of hydrogels. Materials science & engineering. C, Materials for biological applications\| PubMed ID: 26838916	2016
Spectroscopic, Structural, and Computational Characterization of Three Bispidinone Derivatives, as Ligands for Enantioselective Metal Catalyzed Reactions. Chirality\| PubMed ID: 26899470	2016
Organocatalytic vinylogous Mannich reaction of trimethylsiloxyfuran with isatin-derived benzhydryl-ketimines. Organic & biomolecular chemistry\| PubMed ID: 27470306	2016