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JoVE Journal
Bioengineering

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The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
 

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

Article doi: 10.3791/54445
October 7th, 2016

Summary October 7th, 2016

We present a protocol for the synthesis of RGD-functionalized hydrogels as devices for cell and drug delivery. The procedure involves copper catalyzed alkyne-azide cycloaddition (CuAAC) between alkyne-modified polyacrylic acid (PAA) and a RGD-azide derivative. The hydrogels are formed using microwave-assisted polycondensation and their physicochemical properties are investigated.

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