Ching-Kang Chen

Department of Ophthalmology, Baylor College of Medicine

Affiliated withBaylor College of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2016

Other Publications

Article	Year
Evidence for two apoptotic pathways in light-induced retinal degeneration. Nature genetics\| PubMed ID: 12219089	2002
Recoverin and rhodopsin kinase. Advances in experimental medicine and biology\| PubMed ID: 12596917	2002
Palmitoylation regulates regulators of G-protein signaling (RGS) 16 function. I. Mutation of amino-terminal cysteine residues on RGS16 prevents its targeting to lipid rafts and palmitoylatio... The Journal of biological chemistry\| PubMed ID: 12642593	2003
Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12738888	2003
Light-dependent redistribution of visual arrestins and transducin subunits in mice with defective phototransduction. Molecular vision\| PubMed ID: 12802257	2003
RGS9 modulates dopamine signaling in the basal ganglia. Neuron\| PubMed ID: 12818179	2003
Retinal remodeling triggered by photoreceptor degenerations. The Journal of comparative neurology\| PubMed ID: 12866125	2003
Prolonged photoresponses and defective adaptation in rods of Gbeta5-/- mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12904457	2003
Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein. The Journal of biological chemistry\| PubMed ID: 14561760	2004
Novel form of adaptation in mouse retinal rods speeds recovery of phototransduction. The Journal of general physiology\| PubMed ID: 14610022	2003
The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14614075	2003
Rhodopsin-iCre transgenic mouse line for Cre-mediated rod-specific gene targeting. Genesis (New York, N.Y. : 2000)\| PubMed ID: 15682388	2005
D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15728856	2005
Transducin activation state controls its light-dependent translocation in rod photoreceptors. The Journal of biological chemistry\| PubMed ID: 16207703	2005
Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16421323	2006
GAP-independent termination of photoreceptor light response by excess gamma subunit of the cGMP-phosphodiesterase. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16641226	2006
Phototransduction in a transgenic mouse model of Nougaret night blindness. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16793893	2006
RGS expression rate-limits recovery of rod photoresponses. Neuron\| PubMed ID: 16908407	2006
Transducin translocation in rods is triggered by saturation of the GTPase-activating complex. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17267570	2007
Subunit dissociation and diffusion determine the subcellular localization of rod and cone transducins. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17507570	2007
Sphingosine-1-phosphate and endothelin-1 induce the expression of rgs16 protein in cardiac myocytes by transcriptional activation of the rgs16 gene. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 18046543	2008
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18094251	2007
Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18094259	2007
Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18434540	2008
Role of LPA4/p2y9/GPR23 in negative regulation of cell motility. Molecular biology of the cell\| PubMed ID: 18843048	2008
Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites. Investigative ophthalmology & visual science\| PubMed ID: 19797210	2010
Trafficking of membrane proteins to cone but not rod outer segments is dependent on heterotrimeric kinesin-II. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19906976	2009
Background light produces a recoverin-dependent modulation of activated-rhodopsin lifetime in mouse rods. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20107049	2010
Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20164334	2010
The role of Gβ5 in vision. Progress in molecular biology and translational science\| PubMed ID: 20374718	2009
RGS6, a modulator of parasympathetic activation in heart. Circulation research\| PubMed ID: 20864673	2010
Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylation. Investigative ophthalmology & visual science\| PubMed ID: 21398289	2011
Nicotinic excitatory postsynaptic potentials in hippocampal CA1 interneurons are predominantly mediated by nicotinic receptors that contain α4 and β2 subunits. Neuropharmacology\| PubMed ID: 21878344	2011
Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice. Journal of neurochemistry\| PubMed ID: 21883221	2011
Modulation of CREB in the dorsal lateral geniculate nucleus of dark-reared mice. Neural plasticity\| PubMed ID: 22292123	2012
Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice. The Journal of biological chemistry\| PubMed ID: 22371490	2012
The relationship between slow photoresponse recovery rate and temporal resolution of vision. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23055507	2012
Modulation of mouse rod response decay by rhodopsin kinase and recoverin. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23136436	2012
Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23479632	2013
Light-induced translocation of RGS9-1 and Gβ5L in mouse rod photoreceptors. PloS one\| PubMed ID: 23555598	2013
Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23637185	2013
G protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalization. PloS one\| PubMed ID: 25162404	2014
Visual defects in a mouse model of fetal alcohol spectrum disorder. Frontiers in pediatrics\| PubMed ID: 25346924	2014
Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation. Molecular pharmacology\| PubMed ID: 25657338	2015
Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling. PloS one\| PubMed ID: 25659125	2015
Rhodopsin kinase and recoverin modulate phosphodiesterase during mouse photoreceptor light adaptation. The Journal of general physiology\| PubMed ID: 25667411	2015
RGS Protein Regulation of Phototransduction. Progress in molecular biology and translational science\| PubMed ID: 26123301	2015
A Novel Retinal Oscillation Mechanism in an Autosomal Dominant Photoreceptor Degeneration Mouse Model. Frontiers in cellular neuroscience\| PubMed ID: 26793064	2015