J. Steven Alexander

Molecular and Cellular Physiology, Louisiana State University Health Sciences Center in Shreveport

Affiliated withLouisiana State University Health Sciences Center in Shreveport LSU Health Shreveport

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 10	2016
Publication title	2024

Other Publications

Article	Year
Mild hypothermia induced before cardiac arrest reduces brain edema formation in rats. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine\| PubMed ID: 11825833	2002
Endothelial junctional protein redistribution and increased monolayer permeability in human umbilical vein endothelial cells isolated during preeclampsia. American journal of obstetrics and gynecology\| PubMed ID: 11854638	2002
Extravascular transport of fluorescently labeled albumins in the rat mesentery. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 12080415	2002
Identification of an occludin cell adhesion recognition sequence. Inflammation\| PubMed ID: 12184633	2002
Devic disease: clinical course, pathophysiology, and management. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 12385963	2002
Is the gastric epithelial barrier regulated by cadherin recruitment? European journal of gastroenterology & hepatology\| PubMed ID: 12468947	2002
Transfection of IL-10 expression vectors into endothelial cultures attenuates alpha4beta7-dependent lymphocyte adhesion mediated by MAdCAM-1. BMC gastroenterology\| PubMed ID: 12625840	2003
The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor pravastatin reduces disease activity and inflammation in dextran-sulfate induced colitis. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12649355	2003
Randomized, placebo-controlled, double blind, crossover design trial of the efficacy and safety of Zestra for Women in women with and without female sexual arousal disorder. Journal of sex & marital therapy\| PubMed ID: 12735087	2003
Serum from patients with multiple sclerosis downregulates occludin and VE-cadherin expression in cultured endothelial cells. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 12814168	2003
Gamma knife irradiation increases cerebral endothelial expression of intercellular adhesion molecule 1 and E-selectin. Neurosurgery\| PubMed ID: 12823884	2003
Tight junction peptide antagonists enhance neutrophil trans-endothelial chemotaxis. Life sciences\| PubMed ID: 12875904	2003
Blood-brain barrier disruption in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 14664465	2003
Increased disease activity in eNOS-deficient mice in experimental colitis. Free radical biology & medicine\| PubMed ID: 14680690	2003
Role of prostaglandins in maintaining gastric mucus-cell permeability against acid exposure. The Journal of laboratory and clinical medicine\| PubMed ID: 14749685	2004
Stereotactic radiosurgery using the Leksell Gamma Knife: current trends and future directives. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 14766419	2004
CYP450 dietary inhibitors attenuate TNF-alpha-stimulated endothelial molecule expression and leukocyte adhesion. American journal of physiology. Cell physiology\| PubMed ID: 15001427	2004
Human cytomegalovirus induces monocyte differentiation and migration as a strategy for dissemination and persistence. Journal of virology\| PubMed ID: 15078925	2004
Effect of ifenprodil, a polyamine site NMDA receptor antagonist, on brain edema formation following asphyxial cardiac arrest in rats. Resuscitation\| PubMed ID: 15135198	2004
Pathogenesis of brain and spinal cord atrophy in multiple sclerosis. Journal of neuroimaging : official journal of the American Society of Neuroimaging\| PubMed ID: 15228754	2004
HIV-associated dementia, Alzheimer's disease, multiple sclerosis, and schizophrenia: gene expression review. Journal of the neurological sciences\| PubMed ID: 15450765	2004
Cerebral cortical aquaporin-4 expression in brain edema following cardiac arrest in rats. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine\| PubMed ID: 15466140	2004
Mmp-9 deficiency enhances collagenase-induced intracerebral hemorrhage and brain injury in mutant mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15529013	2004
Near-infrared spectroscopy: a tool to monitor cerebral hemodynamic and metabolic changes after cardiac arrest in rats. Resuscitation\| PubMed ID: 15531074	2004
Troglitazone, a PPAR-gamma activator prevents endothelial cell adhesion molecule expression and lymphocyte adhesion mediated by TNF-alpha. BMC physiology\| PubMed ID: 15694007	2005
Apolipoprotein A-IV attenuates oxidant-induced apoptosis in mitotic competent, undifferentiated cells by modulating intracellular glutathione redox balance. American journal of physiology. Cell physiology\| PubMed ID: 16120654	2006
DSS-induced colitis is exacerbated in STAT-6 knockout mice. Inflammatory bowel diseases\| PubMed ID: 16189417	2005
Reversal of experimental colitis disease activity in mice following administration of an adenoviral IL-10 vector. Journal of inflammation (London, England)\| PubMed ID: 16259632	2005
The role of alpha-4 integrin in the aetiology of multiple sclerosis: current knowledge and therapeutic implications. CNS drugs\| PubMed ID: 16268663	2005
VEGF-A stimulation of leukocyte adhesion to colonic microvascular endothelium: implications for inflammatory bowel disease. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 16293653	2006
Effects of peroxynitrite and superoxide radicals on endothelial monolayer permeability: potential role of peroxynitrite in preeclampsia. Journal of the Society for Gynecologic Investigation\| PubMed ID: 16325748	2005
Insulin prevents oxidant-induced endothelial cell barrier dysfunction via nitric oxide-dependent pathway. Surgery\| PubMed ID: 16364721	2006
Expression of lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1) in the human placenta. Lymphatic research and biology\| PubMed ID: 16569201	2006
Multiple sclerosis as a vascular disease. Neurological research\| PubMed ID: 16687046	2006
CD40-CD40 ligand mediates the recruitment of leukocytes and platelets in the inflamed murine colon. Gastroenterology\| PubMed ID: 17324402	2007
The destructive alliance: interactions of leukocytes, cerebral endothelial cells, and the immune cascade in pathogenesis of multiple sclerosis. International review of neurobiology\| PubMed ID: 17531835	2007
Cell-derived microparticles and exosomes in neuroinflammatory disorders. International review of neurobiology\| PubMed ID: 17531844	2007
Evolving therapies for multiple sclerosis. International review of neurobiology\| PubMed ID: 17531859	2007
Platelet-associated NAD(P)H oxidase contributes to the thrombogenic phenotype induced by hypercholesterolemia. Free radical biology & medicine\| PubMed ID: 17561090	2007
HIV antiretroviral drug combination induces endothelial mitochondrial dysfunction and reactive oxygen species production, but not apoptosis. Toxicology and applied pharmacology\| PubMed ID: 17669453	2007
Inflammatory cytokines induce MAdCAM-1 in murine hepatic endothelial cells and mediate alpha-4 beta-7 integrin dependent lymphocyte endothelial adhesion in vitro. BMC physiology\| PubMed ID: 17868448	2007
Proteomic analysis of human cerebral endothelial cells activated by multiple sclerosis serum and IFNbeta-1b. Journal of molecular neuroscience : MN\| PubMed ID: 17873362	2007
Clinical and neuroimaging correlates of antiphospholipid antibodies in multiple sclerosis: a preliminary study. BMC neurology\| PubMed ID: 17945023	2007
Combination therapy with interferon beta-1a and doxycycline in multiple sclerosis: an open-label trial. Archives of neurology\| PubMed ID: 18071030	2008
NeuroAIDS: characteristics and diagnosis of the neurological complications of AIDS. Molecular diagnosis & therapy\| PubMed ID: 18288880	2008
Evidence of platelet activation in multiple sclerosis. Journal of neuroinflammation\| PubMed ID: 18588683	2008
Proteomic analysis of human cerebral endothelial cells activated by glutamate/MK-801: significance in ischemic stroke injury. Journal of molecular neuroscience : MN\| PubMed ID: 18843451	2009
Isotope tracing enhancement of chemiluminescence assays for nitric oxide research. Biological chemistry\| PubMed ID: 19040352	2009
Placenta-derived chymotrypsin-like protease (CLP) disturbs endothelial junctional structure in preeclampsia. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 19126871	2009
Chymotrypsin-like protease (chymase) mediates endothelial activation by factors derived from preeclamptic placentas. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 19494363	2009
Potential roles of cell-derived microparticles in ischemic brain disease. Neurological research\| PubMed ID: 19723448	2009
Angiopoietin-2 in experimental colitis. Inflammatory bowel diseases\| PubMed ID: 19902545	2010
Editorial: Lymphatic vessel functions in Health and Disease. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 20005084	2010
Alemtuzumab and multiple sclerosis: therapeutic application. Expert opinion on biological therapy\| PubMed ID: 20095876	2010
Induction of neuro-protective/regenerative genes in stem cells infiltrating post-ischemic brain tissue. Experimental & translational stroke medicine\| PubMed ID: 20509949	2010
Multiple sclerosis and cerebral endothelial dysfunction: Mechanisms. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 20663648	2011
Elevated plasma chymotrypsin-like protease (chymase) activity in women with preeclampsia. Hypertension in pregnancy\| PubMed ID: 20670150	2010
Analysis of in vitro transfection by sonoporation using cationic and neutral microbubbles. Ultrasound in medicine & biology\| PubMed ID: 20800945	2010
VEGF₁₆₄ differentially regulates neutrophil and T cell adhesion through ItgaL- and ItgaM-dependent mechanisms. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 20884890	2010
Emerging roles of lymphatics in inflammatory bowel disease. Annals of the New York Academy of Sciences\| PubMed ID: 20961310	2010
Murine rVEGF164b, an inhibitory VEGF reduces VEGF-A-dependent endothelial proliferation and barrier dysfunction. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 21040119	2010
Selectin-mediated recruitment of bone marrow stromal cells in the postischemic cerebral microvasculature. Stroke; a journal of cerebral circulation\| PubMed ID: 21257828	2011
Role of the endothelium in inflammatory bowel diseases. World journal of gastroenterology\| PubMed ID: 21350707	2011
The effects of high dose interferon-β1a on plasma microparticles: correlation with MRI parameters. Journal of neuroinflammation\| PubMed ID: 21554694	2011
Complement in neurobiology. Frontiers in bioscience (Landmark edition)\| PubMed ID: 21622213	2011
Analysis of endothelial barrier function in vitro. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21874457	2011
Cryptotanshinone inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3/ERK and small GTPase pathways. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 21881029	2011
Synergistic effect of resveratrol and quercetin released from drug-eluting polymer coatings for endovascular devices. Journal of biomedical materials research. Part B, Applied biomaterials\| PubMed ID: 21948767	2011
Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro. Journal of neuroinflammation\| PubMed ID: 22112345	2011
Interferon-beta-1b protects against multiple sclerosis-induced endothelial cells apoptosis. Frontiers in bioscience (Elite edition)\| PubMed ID: 22201961	2012
Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression. Neoplasia (New York, N.Y.)\| PubMed ID: 22496622	2012
Introduction: brain injury. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 22503573	2013
Integrins and their extracellular matrix ligands in lymphangiogenesis and lymph node metastasis. International journal of cell biology\| PubMed ID: 22505936	2012
Angiopoietins as promising biomarkers and potential therapeutic targets in brain injury. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 22633746	2013
Immunopathological patterns from EAE and Theiler's virus infection: Is multiple sclerosis a homogenous 1-stage or heterogenous 2-stage disease? Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 22633747	2013
Plasma ubiquitin-proteasome system profile in patients with multiple sclerosis: correlation with clinical features, neuroimaging, and treatment with interferon-beta-1b. Neurological research\| PubMed ID: 22709658	2012
Emerging roles of endothelial cells in multiple sclerosis pathophysiology and therapy. Neurological research\| PubMed ID: 22828184	2012
Enhancing the adhesion of hematopoietic precursor cell integrins with hydrogen peroxide increases recruitment within murine gut. Cell transplantation\| PubMed ID: 22889470	2013
Acute carbonyl stress induces occludin glycation and brain microvascular endothelial barrier dysfunction: role for glutathione-dependent metabolism of methylglyoxal. Free radical biology & medicine\| PubMed ID: 23108103	2013
Does pelvic mesh treated with phosphorylcholine improve outcomes? An early experience. European journal of obstetrics, gynecology, and reproductive biology\| PubMed ID: 23280282	2013
Lymphatic vessels are essential for the removal of cholesterol from peripheral tissues by SR-BI-mediated transport of HDL. Cell metabolism\| PubMed ID: 23663736	2013
Improved wound healing of postischemic cutaneous flaps with the use of bone marrow-derived stem cells. The Laryngoscope\| PubMed ID: 23818296	2014
A recombinant inhibitory isoform of vascular endothelial growth factor164/165 aggravates ischemic brain damage in a mouse model of focal cerebral ischemia. The American journal of pathology\| PubMed ID: 23906811	2013
VEGF-A isoform modulation in an preclinical TNBS model of ulcerative colitis: protective effects of a VEGF164b therapy. Journal of translational medicine\| PubMed ID: 24020796	2013
Role of chymase in preeclampsia. Current vascular pharmacology\| PubMed ID: 24063379	2013
Photothermolysis of lymphatic endothelial cells by gold nanoshell-mediated hyperthermia. Journal of nanoscience and nanotechnology\| PubMed ID: 24758030	2014
Bioinformatics multivariate analysis determined a set of phase-specific biomarker candidates in a novel mouse model for viral myocarditis. Circulation. Cardiovascular genetics\| PubMed ID: 25031303	2014
Preface of the special issue - "Africa". Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 25236675	2014
Distinct kinetics of viral replication, T cell infiltration, and fibrosis in three phases of myocarditis following Theiler's virus infection. Cellular immunology\| PubMed ID: 25460083	2014
Dual signals underlying diabetic lymphatic barrier dysregulation. Cardiovascular research\| PubMed ID: 25994173	2015
Evidence for Nontraditional Lymphatics in the Choroid. Investigative ophthalmology & visual science\| PubMed ID: 26241180	2015
"Microglial nodules" and "newly forming lesions" may be a Janus face of early MS lesions; implications from virus-induced demyelination, the Inside-Out model. BMC neurology\| PubMed ID: 26499989	2015
1,25(OH)2D3 Induces Placental Vascular Smooth Muscle Cell Relaxation by Phosphorylation of Myosin Phosphatase Target Subunit 1Ser507: Potential Beneficial Effects of Vitamin D on Placental V... Biology of reproduction\| PubMed ID: 27075619	2016
Substitution with Alternative Anti-TNFα Therapy (SAVANT)-Outcomes of a Crohn's Disease Cohort Undergoing Substitution Therapy with Certolizumab. Inflammatory bowel diseases\| PubMed ID: 27104819	2016
Sulforaphane induces neurovascular protection against a systemic inflammatory challenge via both Nrf2-dependent and independent pathways. Vascular pharmacology\| PubMed ID: 27401964	2016
From trash to treasure: The untapped potential of endothelial microparticles in neurovascular diseases. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 27531185	2016
Hydrogen sulfide metabolism regulates endothelial solute barrier function. Redox biology\| PubMed ID: 27552214	2016
Three-dimensional printing of bioactive hernia meshes: In vitro proof of principle. Surgery\| PubMed ID: 27726915	2016
Plasma hydrogen sulfide: A biomarker of Alzheimer's disease and related dementias. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 33710769	2021
Construction and Performance Testing of a Fast-Assembly COVID-19 (FALCON) Emergency Ventilator in a Model of Normal and Low-Pulmonary Compliance Conditions. Frontiers in physiology\| PubMed ID: 33868006	2021
Efficacy and safety testing of a COVID-19 era emergency ventilator in a healthy rabbit lung model. BMC biomedical engineering\| PubMed ID: 35287761	2022
The Renaissance of -The Flagship Journal of the International Society for Pathophysiology. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 35366253	2020
Experimental validation of a portable tidal volume indicator for bag valve mask ventilation. BMC biomedical engineering\| PubMed ID: 36384855	2022
Elevated plasma sulfides are associated with cognitive dysfunction and brain atrophy in human Alzheimer's disease and related dementias. Redox biology\| PubMed ID: 36924684	2023
'Distraction Vaginogenesis': Preliminary Results Using a Novel Method for Vaginal Canal Expansion in Rats. Bioengineering (Basel, Switzerland)\| PubMed ID: 36978742	2023
Histologic Analysis of 'Distraction Vaginogenesis' in a Rat Model. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 38921727	2024
Distraction Enterogenesis in Rats: A Novel Approach for the Treatment of Short Bowel Syndrome. Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 39189165	2024
Enhanced Manual Ventilation with a Handheld Audiovisual Device - BENGI - Insights from a Pilot Study in Special Operations Medicine. Journal of special operations medicine : a peer reviewed journal for SOF medical professionals\| PubMed ID: 39285506	2024
Pathophysiology and Prevention of Manual-Ventilation-Induced Lung Injury (MVILI). Pathophysiology : the official journal of the International Society for Pathophysiology\| PubMed ID: 39449524	2024