Michael Reth

Max-Planck Institute for Immunobiology und Epigenetics

Affiliated withMax-Planck Institute for Immunobiology und Epigenetics University of Freiburg Albert-Ludwigs-Universität

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2016

Other Publications

Article	Year
Cre recombinase-controlled expression of the mb-1 allele. Genesis (New York, N.Y. : 2000)\| PubMed ID: 11857807	2002
The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11917123	2002
The role of SHIP in mast cell degranulation and IgE-induced mast cell survival. Immunology letters\| PubMed ID: 12008029	2002
B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12097390	2002
BCR mutants deficient in ligand-independent and more sensitive for ligand-dependent signaling. European journal of immunology\| PubMed ID: 12115644	2002
Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling. The EMBO journal\| PubMed ID: 12411479	2002
The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion. Nature immunology\| PubMed ID: 12436112	2003
Hydrogen peroxide as second messenger in lymphocyte activation. Nature immunology\| PubMed ID: 12447370	2002
Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop. Molecular cell\| PubMed ID: 12453414	2002
Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain. International journal of cancer\| PubMed ID: 12471624	2003
Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nature immunology\| PubMed ID: 12563261	2003
NF-kappaB is required for cell death induction by latent membrane protein 1 of Epstein-Barr virus. Cellular signalling\| PubMed ID: 12618217	2003
Genetic changes occurring in established tumors rapidly stimulate new antibody responses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12702750	2003
Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia. Nature\| PubMed ID: 12761551	2003
Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers. Transplantation\| PubMed ID: 12811248	2003
Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells. The Journal of experimental medicine\| PubMed ID: 12835482	2003
A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12886015	2003
Importance of TRF1 for functional telomere structure. The Journal of biological chemistry\| PubMed ID: 14559908	2004
B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling. European journal of immunology\| PubMed ID: 14635051	2003
Identification of a pre-BCR lacking surrogate light chain. The Journal of experimental medicine\| PubMed ID: 14638847	2003
Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf. Oncogene\| PubMed ID: 14654779	2003
Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells. The Journal of biological chemistry\| PubMed ID: 14747471	2004
A revised and complete map of the chicken c-mil/raf-1 locus. Oncogene\| PubMed ID: 14968114	2004
Feedback regulation of lymphocyte signalling. Nature reviews. Immunology\| PubMed ID: 15057785	2004
B cell antigen receptor assembly and Syk activation in the S2 cell reconstitution system. Immunology letters\| PubMed ID: 15081529	2004
Functional folding of a cytoplasmic single-chain variable fragment and its use as elutable protein purification tag. Immunology letters\| PubMed ID: 15081544	2004
B-cell signal transduction: tyrosine phosphorylation, kinase activity, and calcium mobilization. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15146122	2004
Perspectives on the nature of BCR-mediated survival signals. Molecular cell\| PubMed ID: 15200948	2004
Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors. European journal of immunology\| PubMed ID: 15580656	2005
Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line. Biochemical and biophysical research communications\| PubMed ID: 15629431	2005
A leucine zipper in the N terminus confers membrane association to SLP-65. Nature immunology\| PubMed ID: 15654340	2005
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature\| PubMed ID: 15703750	2005
B cell signaling and tumorigenesis. Annual review of immunology\| PubMed ID: 15771577	2005
Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes. Immunology letters\| PubMed ID: 16356554	2006
Human T-cell leukemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kappaB. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 16436054	2006
Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation. Immunity\| PubMed ID: 16782029	2006
Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system. International immunology\| PubMed ID: 16877534	2006
Association of protein kinase C-delta with the B cell antigen receptor complex. Cellular signalling\| PubMed ID: 17098397	2007
Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination. Journal of hepatology\| PubMed ID: 17434229	2007
Yin Yang 1 is a critical regulator of B-cell development. Genes & development\| PubMed ID: 17504937	2007
Immunoreceptors and integrins. Immunological reviews\| PubMed ID: 17624940	2007
Mutations of the Igbeta gene cause agammaglobulinemia in man. The Journal of experimental medicine\| PubMed ID: 17709424	2007
The TCR binding site does move. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17925433	2007
The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development. The EMBO journal\| PubMed ID: 18369315	2008
SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway. Nature immunology\| PubMed ID: 18488031	2008
Functional analysis of histone methyltransferase g9a in B and T lymphocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18566414	2008
Enhanced B-cell activation mediated by TLR4 and BCR crosstalk. European journal of immunology\| PubMed ID: 18819072	2008
Clustering models. Advances in experimental medicine and biology\| PubMed ID: 19065784	2008
Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19109166	2009
Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling. Nature reviews. Immunology\| PubMed ID: 19240758	2009
Molecular components of the B-cell antigen receptor complex of the IgM class. 1990. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19620316	2009
Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood\| PubMed ID: 19812384	2009
Autoinhibition and adapter function of Syk. Immunological reviews\| PubMed ID: 19909371	2009
Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling. Immunology letters\| PubMed ID: 20005895	2010
Voltage control for B cell activation. Nature immunology\| PubMed ID: 20157299	2010
Arginine methylation of the B cell antigen receptor promotes differentiation. The Journal of experimental medicine\| PubMed ID: 20231378	2010
N-linked glycosylation selectively regulates autonomous precursor BCR function. Nature immunology\| PubMed ID: 20622883	2010
Oligomeric organization of the B-cell antigen receptor on resting cells. Nature\| PubMed ID: 20818374	2010
The dissociation activation model of B cell antigen receptor triggering. FEBS letters\| PubMed ID: 20920502	2010
Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20940318	2010
B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21187409	2011
B cells that produce immunoglobulin E mediate colitis in BALB/c mice. Gastroenterology\| PubMed ID: 21983080	2012
Bacillus subtilis MreB orthologs self-organize into filamentous structures underneath the cell membrane in a heterologous cell system. PloS one\| PubMed ID: 22069484	2011
Drosophila S2 Schneider cells: a useful tool for rebuilding and redesigning approaches in synthetic biology. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22083752	2012
The SH2-domain of SHIP1 interacts with the SHIP1 C-terminus: impact on SHIP1/Ig-α interaction. Biochimica et biophysica acta\| PubMed ID: 22182704	2012
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. The Journal of experimental medicine\| PubMed ID: 22213803	2012
Synthetic immune signaling. Current opinion in biotechnology\| PubMed ID: 22326912	2012
Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors. Blood\| PubMed ID: 22517907	2012
Immunoglobulins drive terminal maturation of splenic dendritic cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23345431	2013
Semi-supervised prediction of SH2-peptide interactions from imbalanced high-throughput data. PloS one\| PubMed ID: 23690949	2013
CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23836650	2013
Matching cellular dimensions with molecular sizes. Nature immunology\| PubMed ID: 23867923	2013
The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination. PloS one\| PubMed ID: 23874770	2013
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells. Cell\| PubMed ID: 23953116	2013
Proximity ligation assay for high-content profiling of cell signaling pathways on a microfluidic chip. Molecular & cellular proteomics : MCP\| PubMed ID: 24072685	2013
Pre-clustering of the B cell antigen receptor demonstrated by mathematically extended electron microscopy. Frontiers in immunology\| PubMed ID: 24367367	2013
Michael Neuberger (1953-2013). Immunity\| PubMed ID: 24479157	2013
Signaling circuits in early B-cell development. Advances in immunology\| PubMed ID: 24507157	2014
The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity. The Journal of experimental medicine\| PubMed ID: 24590766	2014
Pillars article: antigen receptor tail clue. Nature. 1989. 338: 383-384. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24748635	2014
MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24760155	2014
The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24790146	2014
The role of the Syk/Shp-1 kinase-phosphatase equilibrium in B cell development and signaling. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24899508	2014
B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk. eLife\| PubMed ID: 24963139	2014
PDK1 regulates B cell differentiation and homeostasis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24979759	2014
Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE. European journal of immunology\| PubMed ID: 25044405	2014
The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells. The Journal of experimental medicine\| PubMed ID: 25288397	2014
Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms. European journal of immunology\| PubMed ID: 25382621	2015
The nanoscale organization of the B lymphocyte membrane. Biochimica et biophysica acta\| PubMed ID: 25450974	2015
CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. The EMBO journal\| PubMed ID: 25630702	2015
Preface to special issue on nanoscale membrane organisations. Biochimica et biophysica acta\| PubMed ID: 25677899	2015
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature\| PubMed ID: 25686605	2015
TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition. Developmental cell\| PubMed ID: 25727005	2015
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature\| PubMed ID: 25799995	2015
Responsiveness of B cells is regulated by the hinge region of IgD. Nature immunology\| PubMed ID: 25848865	2015
Erratum: Responsiveness of B cells is regulated by the hinge region of IgD. Nature immunology\| PubMed ID: 26086144	2015
Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26157172	2015
Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation. The Journal of experimental medicine\| PubMed ID: 26324445	2015
B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation. Science signaling\| PubMed ID: 26373673	2015
Receptor Dissociation and B-Cell Activation. Current topics in microbiology and immunology\| PubMed ID: 26428245	2016
Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26843325	2016
Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature\| PubMed ID: 26958840	2016
Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens. The EMBO journal\| PubMed ID: 27634959	2016
What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling. European journal of immunology\| PubMed ID: 27813071	2016