Marie-Dominique Filippi

Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Research Foundation

Affiliated withCincinnati Children’s Research Foundation

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2016

Other Publications

Article	Year
Requirement for mitogen-activated protein kinase activation in the response of embryonic stem cell-derived hematopoietic cells to thrombopoietin in vitro. Blood\| PubMed ID: 11830463	2002
The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization. Blood\| PubMed ID: 12176888	2002
Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science (New York, N.Y.)\| PubMed ID: 14564009	2003
Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. Nature immunology\| PubMed ID: 15170212	2004
Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15814684	2005
Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment. Blood\| PubMed ID: 16174757	2006
Rho GTPase CDC42 regulates directionality and random movement via distinct MAPK pathways in neutrophils. Blood\| PubMed ID: 16931627	2006
Rho GTPase Rac1 is critical for neutrophil migration into the lung. Blood\| PubMed ID: 16990606	2007
GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis. The New England journal of medicine\| PubMed ID: 17287477	2007
The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress. Blood\| PubMed ID: 18048646	2008
Cutaneous infection with Metarhizium anisopliae in a patient with hypohidrotic ectodermal dysplasia and immune deficiency. The Pediatric infectious disease journal\| PubMed ID: 18277915	2008
Mast cells can contribute to axon-glial dissociation and fibrosis in peripheral nerve. Neuron glia biology\| PubMed ID: 18634614	2007
Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease. Nature\| PubMed ID: 19242412	2009
Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones. Blood\| PubMed ID: 19357397	2009
Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential. Blood\| PubMed ID: 19713466	2009
The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling. Blood\| PubMed ID: 19752396	2009
Rho GTPases in hematopoiesis and hemopathies. Blood\| PubMed ID: 19965643	2010
Differential effects of kidney-lung cross-talk during acute kidney injury and bacterial pneumonia. Kidney international\| PubMed ID: 21734638	2011
Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation. Chemistry & biology\| PubMed ID: 22365606	2012
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell stem cell\| PubMed ID: 22560076	2012
Cdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubules. Blood\| PubMed ID: 22932798	2012
An efficient and reproducible process for transmission electron microscopy (TEM) of rare cell populations. Journal of immunological methods\| PubMed ID: 24291346	2014
ATF3 is a novel regulator of mouse neutrophil migration. Blood\| PubMed ID: 24470589	2014
New regulatory role for SRF in neutrophils. Blood\| PubMed ID: 24810621	2014
The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation. The Journal of experimental medicine\| PubMed ID: 25092872	2014
Neutrophils scan for activated platelets to initiate inflammation. Science (New York, N.Y.)\| PubMed ID: 25477463	2014
RhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation. The Journal of allergy and clinical immunology\| PubMed ID: 26100081	2016
Neutrophil actin regulation: MKL1 is in control. Blood\| PubMed ID: 26405212	2015
Leukocyte transcellular diapedesis: Rap1b is in control. Tissue barriers\| PubMed ID: 26451346	2015
Mechanism of Diapedesis: Importance of the Transcellular Route. Advances in immunology\| PubMed ID: 26791857	2016