Bart Spee

Department of Clinical Sciences of Companion Animals, Utrecht University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2016

Other Publications

Article	Year
Detection of Helicobacter pylori in bile of cats. FEMS immunology and medical microbiology\| PubMed ID: 15477044	2004
The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns. Comparative hepatology\| PubMed ID: 15566568	2004
Differential expression of copper-associated and oxidative stress related proteins in a new variant of copper toxicosis in Doberman pinschers. Comparative hepatology\| PubMed ID: 15790412	2005
Quantitative PCR method to detect a 13-kb deletion in the MURR1 gene associated with copper toxicosis and HIV-1 replication. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 16075372	2005
Regenerative and fibrotic pathways in canine hepatic portosystemic shunt and portal vein hypoplasia, new models for clinical hepatocyte growth factor treatment. Comparative hepatology\| PubMed ID: 16336649	2005
Transforming growth factor beta-1 signalling in canine hepatic diseases: new models for human fibrotic liver pathologies. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 16842329	2006
Development and evaluation of canine reference genes for accurate quantification of gene expression. Analytical biochemistry\| PubMed ID: 16844072	2006
Specific down-regulation of XIAP with RNA interference enhances the sensitivity of canine tumor cell-lines to TRAIL and doxorubicin. Molecular cancer\| PubMed ID: 16953886	2006
Copper metabolism and oxidative stress in chronic inflammatory and cholestatic liver diseases in dogs. Journal of veterinary internal medicine\| PubMed ID: 17063700	2006
Major HGF-mediated regenerative pathways are similarly affected in human and canine cirrhosis. Comparative hepatology\| PubMed ID: 17672890	2007
Hepatocyte growth factor improves viability after H2O2-induced toxicity in bile duct epithelial cells. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP\| PubMed ID: 18234561	2008
In vitro and in vivo bioactivity of recombinant canine hepatocyte growth factor. Veterinary journal (London, England : 1997)\| PubMed ID: 18314358	2008
Clinicopathological study on cholangiolocellular carcinoma suggesting hepatic progenitor cell origin. Hepatology (Baltimore, Md.)\| PubMed ID: 18393293	2008
In vitro differentiation of liver progenitor cells derived from healthy dog livers. Stem cells and development\| PubMed ID: 18454698	2009
The dog liver contains a "side population" of cells with hepatic progenitor-like characteristics. Stem cells and development\| PubMed ID: 18680393	2009
A GeNorm algorithm-based selection of reference genes for quantitative real-time PCR in skin biopsies of healthy dogs and dogs with atopic dermatitis. Veterinary immunology and immunopathology\| PubMed ID: 19131113	2009
Cross-species immunohistochemical investigation of the activation of the liver progenitor cell niche in different types of liver disease. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 19490419	2009
Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling. Gut\| PubMed ID: 19880964	2010
Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours. Comparative hepatology\| PubMed ID: 20167095	2010
Recombinant hepatocyte growth factor treatment in a canine model of congenital liver hypoplasia. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 21733083	2011
Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors. Gastroenterology\| PubMed ID: 22178589	2012
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nature medicine\| PubMed ID: 22388089	2012
COMMD1-deficient dogs accumulate copper in hepatocytes and provide a good model for chronic hepatitis and fibrosis. PloS one\| PubMed ID: 22879914	2012
Aberrant gene expression in dogs with portosystemic shunts. PloS one\| PubMed ID: 23451256	2013
Altered subcellular localization of heat shock protein 90 is associated with impaired expression of the aryl hydrocarbon receptor pathway in dogs. PloS one\| PubMed ID: 23472125	2013
Safety and efficacy field study of artesunate for dogs with non-resectable tumours. Anticancer research\| PubMed ID: 23645726	2013
Keratin 19: a key role player in the invasion of human hepatocellular carcinomas. Gut\| PubMed ID: 23958557	2014
Classification of primary hepatic tumours in the dog. Veterinary journal (London, England : 1997)\| PubMed ID: 24011584	2013
Potential of regenerative medicine techniques in canine hepatology. The Veterinary quarterly\| PubMed ID: 24422896	2013
Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts. PloS one\| PubMed ID: 24945279	2014
Hepatic progenitor cells in canine and feline medicine: potential for regenerative strategies. BMC veterinary research\| PubMed ID: 24946932	2014
Aberrant expression of copper associated genes after copper accumulation in COMMD1-deficient dogs. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)\| PubMed ID: 25053573	2015
Classification of primary hepatic tumours in the cat. Veterinary journal (London, England : 1997)\| PubMed ID: 25439443	2014
Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells. Biochimica et biophysica acta\| PubMed ID: 25500141	2015
Enhanced Wnt/β-catenin and Notch signalling in the activated canine hepatic progenitor cell niche. BMC veterinary research\| PubMed ID: 25551829	2014
Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids. Stem cell reports\| PubMed ID: 26455412	2015
Characterization and Comparison of Canine Multipotent Stromal Cells Derived from Liver and Bone Marrow. Stem cells and development\| PubMed ID: 26462417	2016
The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders. Disease models & mechanisms\| PubMed ID: 26747866	2016
ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells. Journal of lipid research\| PubMed ID: 27179362	2016
Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb. Oncotarget\| PubMed ID: 27323406	2016