Da-Zhi Wang

Department of Cardiology, Boston Children's Hospital

Affiliated withBoston Children's Hospital Harvard Medical School University of South Florida

Research Area

Biography

Da-Zhi Wang has not added Biography.
If you are Da-Zhi Wang and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 10	2016
Publication title	2025

Other Publications

Article	Year
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell\| PubMed ID: 12297046	2002
Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12397177	2002
Effects of nitrate and phosphate on growth and C2 toxin productivity of Alexandrium tamarense CI01 in culture. Marine pollution bulletin\| PubMed ID: 12398397	2002
Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circulation research\| PubMed ID: 12663482	2003
Myocardin is a master regulator of smooth muscle gene expression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12756293	2003
The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12867591	2003
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature\| PubMed ID: 15014501	2004
Target gene-specific modulation of myocardin activity by GATA transcription factors. Molecular and cellular biology\| PubMed ID: 15367672	2004
Control of smooth muscle development by the myocardin family of transcriptional coactivators. Current opinion in genetics & development\| PubMed ID: 15380248	2004
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex. The Journal of clinical investigation\| PubMed ID: 15489953	2004
Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Molecular and cellular biology\| PubMed ID: 15601857	2005
Myocardin is sufficient and necessary for cardiac gene expression in Xenopus. Development (Cambridge, England)\| PubMed ID: 15673566	2005
Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes. Circulation research\| PubMed ID: 16224060	2005
Myocardin enhances Smad3-mediated transforming growth factor-beta1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22alpha transcription in... Circulation research\| PubMed ID: 16224064	2005
Identification and characterization of a "biomarker of toxicity" from the proteome of the paralytic shellfish toxin-producing dinoflagellate Alexandrium tamarense (Dinophyceae). Proteomics\| PubMed ID: 16342137	2006
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nature genetics\| PubMed ID: 16380711	2006
Myocardin induces cardiomyocyte hypertrophy. Circulation research\| PubMed ID: 16556869	2006
Micro or mega: how important are microRNAs in muscle? Cell cycle (Georgetown, Tex.)\| PubMed ID: 16639081	2006
Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin. Journal of medical sciences (Taipei, Taiwan)\| PubMed ID: 16708114	2005
Systematic evaluation of association between the microsomal glutathione S-transferase 2 common variation and psoriasis vulgaris in Chinese population. Archives of dermatological research\| PubMed ID: 16773312	2006
Paralytic shellfish toxin profiles and toxin variability of the genus Alexandrium (Dinophyceae) isolated from the Southeast China Sea. Toxicon : official journal of the International Society on Toxinology\| PubMed ID: 16859722	2006
Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies. The Journal of biological chemistry\| PubMed ID: 17098737	2007
Follow-up analysis of PSORS9 in 151 Chinese families confirmed the linkage to 4q31-32 and refined the evidence to the families of early-onset psoriasis. The Journal of investigative dermatology\| PubMed ID: 17139270	2007
Influence of N, P additions on the transfer of nickel from phytoplankton to copepods. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 17257722	2007
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. Circulation research\| PubMed ID: 17272810	2007
MicroRNAs in skeletal and cardiac muscle development. DNA and cell biology\| PubMed ID: 17465888	2007
Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. Journal of molecular and cellular cardiology\| PubMed ID: 17498736	2007
Polymorphisms in interleukin-15 gene on chromosome 4q31.2 are associated with psoriasis vulgaris in Chinese population. The Journal of investigative dermatology\| PubMed ID: 17554368	2007
Trophic transfer of paralytic shellfish toxins from the cladoceran (Moina mongolica) to larvae of the fish (Sciaenops ocellatus). Toxicon : official journal of the International Society on Toxinology\| PubMed ID: 17619042	2007
Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17766470	2007
Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17940050	2007
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. The Journal of clinical investigation\| PubMed ID: 18079970	2008
Muscling through the microRNA world. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 18222968	2008
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18256189	2008
Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18296632	2008
Taking microRNAs to heart. Trends in molecular medicine\| PubMed ID: 18457996	2008
Neurotoxins from marine dinoflagellates: a brief review. Marine drugs\| PubMed ID: 18728731	2008
Myocardin marks the earliest cardiac gene expression and plays an important role in heart development. Anatomical record (Hoboken, N.J. : 2007)\| PubMed ID: 18780304	2008
microRNAs and muscle disorders. Journal of cell science\| PubMed ID: 19092056	2009
Effects of macronutrient additions on nickel uptake and distribution in the dinoflagellate Prorocentrum donghaiense Lu. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 19217194	2009
A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19234115	2009
Smooth(ing) muscle differentiation by microRNAs. Cell stem cell\| PubMed ID: 19664984	2009
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. The Journal of clinical investigation\| PubMed ID: 19726871	2009
Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodoma... The Journal of biological chemistry\| PubMed ID: 19797053	2009
MicroRNAs in cardiac development and remodeling. Pediatric cardiology\| PubMed ID: 20135107	2010
The BMP pathway acts to directly regulate Tbx20 in the developing heart. Development (Cambridge, England)\| PubMed ID: 20460370	2010
The emerging role of microRNAs as a therapeutic target for cardiovascular disease. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 20462281	2010
MicroRNAs in cardiac remodeling and disease. Journal of cardiovascular translational research\| PubMed ID: 20560042	2010
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. The Journal of cell biology\| PubMed ID: 20819939	2010
Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20884876	2010
Induction of microRNA-1 by myocardin in smooth muscle cells inhibits cell proliferation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21051663	2011
Application of microRNA in cardiac and skeletal muscle disease gene therapy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21194029	2011
"RISCing" the heart: In vivo identification of cardiac microRNA targets by RISCome. Circulation research\| PubMed ID: 21212388	2011
DOT1L regulates dystrophin expression and is critical for cardiac function. Genes & development\| PubMed ID: 21289070	2011
MicroRNAs in cardiomyocyte development. Wiley interdisciplinary reviews. Systems biology and medicine\| PubMed ID: 21305703	2011
[Detection and application of allelic expression imbalance]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]\| PubMed ID: 21418811	2011
Transgenic overexpression of miR-133a in skeletal muscle. BMC musculoskeletal disorders\| PubMed ID: 21615921	2011
'CArG'ing for microRNAs. Gastroenterology\| PubMed ID: 21620846	2011
Source and profile of paralytic shellfish poisoning toxins in shellfish in Daya Bay, South China Sea. Marine environmental research\| PubMed ID: 21658755	2011
Molecular staging of marine medaka: a model organism for marine ecotoxicity study. Marine pollution bulletin\| PubMed ID: 21708389	2011
The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly. The Journal of cell biology\| PubMed ID: 21859860	2011
miR-155 inhibits expression of the MEF2A protein to repress skeletal muscle differentiation. The Journal of biological chemistry\| PubMed ID: 21868385	2011
Synergistic activation of cardiac genes by myocardin and Tbx5. PloS one\| PubMed ID: 21897873	2011
Identification and Characterization of Cell Wall Proteins of a Toxic Dinoflagellate Alexandrium catenella Using 2-D DIGE and MALDI TOF-TOF Mass Spectrometry. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 21904561	2011
Homology-Driven Proteomics of Dinoflagellates with Unsequenced Genomes Using MALDI-TOF/TOF and Automated De Novo Sequencing. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 21977052	2011
Determination of miRNA targets in skeletal muscle cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22130855	2012
Quantitative proteomic analysis of okadaic acid treated mouse small intestines reveals differentially expressed proteins involved in diarrhetic shellfish poisoning. Journal of proteomics\| PubMed ID: 22270013	2012
microRNAs in cardiovascular development. Journal of molecular and cellular cardiology\| PubMed ID: 22300733	2012
CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circulation research\| PubMed ID: 22343712	2012
MicroRNAs in heart development. Current topics in developmental biology\| PubMed ID: 22449848	2012
Cadmium-induced changes in trace element bioaccumulation and proteomics perspective in four marine bivalves. Environmental toxicology and chemistry\| PubMed ID: 22488592	2012
Xin proteins and intercalated disc maturation, signaling and diseases. Frontiers in bioscience (Landmark edition)\| PubMed ID: 22652799	2012
Quantitative proteomic analysis of differentially expressed proteins in the toxicity-lost mutant of Alexandrium catenella (Dinophyceae) in the exponential phase. Journal of proteomics\| PubMed ID: 22921724	2012
Acetylation of myocardin is required for the activation of cardiac and smooth muscle genes. The Journal of biological chemistry\| PubMed ID: 23007391	2012
Comparative proteomic analysis reveals proteins putatively involved in toxin biosynthesis in the marine dinoflagellate Alexandrium catenella. Marine drugs\| PubMed ID: 23340676	2013
MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circulation research\| PubMed ID: 23524588	2013
Opposite roles of myocardin and atrogin-1 in L6 myoblast differentiation. Journal of cellular physiology\| PubMed ID: 23526547	2013
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circulation research\| PubMed ID: 23575307	2013
Responses of Nannochloropsis oceanica IMET1 to Long-Term Nitrogen Starvation and Recovery. Plant physiology\| PubMed ID: 23637339	2013
Quantitative proteomic analysis reveals evolutionary divergence and species-specific peptides in the Alexandrium tamarense complex (Dinophyceae). Journal of proteomics\| PubMed ID: 23684789	2013
Quantitative proteomic analysis of cell cycle of the dinoflagellate Prorocentrum donghaiense (Dinophyceae). PloS one\| PubMed ID: 23691081	2013
Build a braveheart: the missing linc (RNA). Circulation research\| PubMed ID: 23743224	2013
MicroRNAs in cardiac regeneration and cardiovascular disease. Science China. Life sciences\| PubMed ID: 23974704	2013
Marine metaproteomics: current status and future directions. Journal of proteomics\| PubMed ID: 24041543	2014
Marine dinoflagellate proteomics: current status and future perspectives. Journal of proteomics\| PubMed ID: 24503187	2014
Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy. Circulation research\| PubMed ID: 24657879	2014
Crystallin-αB regulates skeletal muscle homeostasis via modulation of argonaute2 activity. The Journal of biological chemistry\| PubMed ID: 24782307	2014
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. Nature medicine\| PubMed ID: 24813252	2014
Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model. Circulation research\| PubMed ID: 24833660	2014
Non-Coding RNAs Including miRNAs and lncRNAs in Cardiovascular Biology and Disease. Cells\| PubMed ID: 25153164	2014
LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity. Circulation\| PubMed ID: 25156994	2014
Generation of a Cre knock-in into the Myocardin locus to mark early cardiac and smooth muscle cell lineages. Genesis (New York, N.Y. : 2000)\| PubMed ID: 25174608	2014
miR-22 in cardiac remodeling and disease. Trends in cardiovascular medicine\| PubMed ID: 25218673	2014
Pi3kcb links Hippo-YAP and PI3K-AKT signaling pathways to promote cardiomyocyte proliferation and survival. Circulation research\| PubMed ID: 25249570	2015
An epigenetic "LINK(RNA)" to pathological cardiac hypertrophy. Cell metabolism\| PubMed ID: 25295782	2014
The myriad essential roles of microRNAs in cardiovascular homeostasis and disease. Genes & diseases\| PubMed ID: 25328909	2014
Comparative transcriptome analysis of a toxin-producing dinoflagellate Alexandrium catenella and its non-toxic mutant. Marine drugs\| PubMed ID: 25421324	2014
Proteomic analysis provides new insights into the adaptive response of a dinoflagellate Prorocentrum donghaiense to changing ambient nitrogen. Plant, cell & environment\| PubMed ID: 25789726	2015
Comparative proteomics reveals highly and differentially expressed proteins in field-collected and laboratory-cultured blooming cells of the diatom Skeletonema costatum. Environmental microbiology\| PubMed ID: 26014042	2015
Novel Roles of GATA4/6 in the Postnatal Heart Identified through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation by Adeno-Associated Virus Delivery of Cre Recombinase. PloS one\| PubMed ID: 26023924	2015
Trbp regulates heart function through microRNA-mediated Sox6 repression. Nature genetics\| PubMed ID: 26029872	2015
Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases. BioMed research international\| PubMed ID: 26258142	2015
Paralytic shellfish toxin biosynthesis in cyanobacteria and dinoflagellates: A molecular overview. Journal of proteomics\| PubMed ID: 26316331	2016
Differential Diagnosis of Malignant Biliary Tract Cancer from Benign Tissues using Apparent Diffusion Coefficient Measurements with Diffusion Weighted Imaging in Asians. Asian Pacific journal of cancer prevention : APJCP\| PubMed ID: 26320508	2015
iTRAQ-based quantitative proteomic analysis of a toxigenic dinoflagellate Alexandrium catenella and its non-toxic mutant. Proteomics\| PubMed ID: 26417864	2015
Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. The Journal of clinical investigation\| PubMed ID: 26436652	2015
Mystery of Trbp, tale of a RBP in the miRNA pathway. Cell cycle (Georgetown, Tex.)\| PubMed ID: 26496166	2015
Trbp Is Required for Differentiation of Myoblasts and Normal Regeneration of Skeletal Muscle. PloS one\| PubMed ID: 27159388	2016
Regulation of Skeletal Muscle by microRNAs. Comprehensive Physiology\| PubMed ID: 27347893	2016
Environmental Microbial Community Proteomics: Status, Challenges and Perspectives. International journal of molecular sciences\| PubMed ID: 27527164	2016
Long non-coding RNAs link extracellular matrix gene expression to ischemic cardiomyopathy. Cardiovascular research\| PubMed ID: 27557636	2016
(MYO)SLIDing Our Way Into the Vascular Pool of Long Noncoding RNAs. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 27655778	2016
Comparative Transcriptomic Analysis Reveals Novel Insights into the Adaptive Response of Skeletonema costatum to Changing Ambient Phosphorus. Frontiers in microbiology\| PubMed ID: 27703451	2016
How cardiomyocytes sense pathophysiological stresses for cardiac remodeling. Cellular and molecular life sciences : CMLS\| PubMed ID: 27714411	2016
New Insights Into the Molecular Underpinnings of LVNC. Circulation\| PubMed ID: 35188799	2022
Regulation of Myogenesis by a Na/K-ATPase α1 Caveolin-Binding Motif. Stem cells (Dayton, Ohio)\| PubMed ID: 35257186	2022
Set7 Deletion Prevents Glucose Intolerance and Improves the Recovery of Cardiac Function After Ischemia and Reperfusion in Obese Female Mice. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 35781359	2022
Defective efferocytosis of vascular cells in heart disease. Frontiers in cardiovascular medicine\| PubMed ID: 36247464	2022
Set7 deletion attenuates isoproterenol-induced cardiac fibrosis and delays cardiac dysfunction. Clinical science (London, England : 1979)\| PubMed ID: 36285636	2022
Promoting Lymphangiogenesis and Lymphatic Growth and Remodeling to Treat Cardiovascular and Metabolic Diseases. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 36453280	2023
Targeting Epsins to Inhibit Fibroblast Growth Factor Signaling While Potentiating Transforming Growth Factor-β Signaling Constrains Endothelial-to-Mesenchymal Transition in Atherosclerosis. Circulation\| PubMed ID: 36591786	2023
Ablation of miRNA-22 protects against obesity-induced adipocyte senescence and ameliorates metabolic disorders in middle-aged mice. Mechanisms of ageing and development\| PubMed ID: 36641038	2023
miRNA-22 is involved in the aortic reactivity in physiological conditions and mediates obesity-induced perivascular adipose tissue dysfunction. Life sciences\| PubMed ID: 36690245	2023
mt-Ty 5'tiRNA regulates skeletal muscle cell proliferation and differentiation. Cell proliferation\| PubMed ID: 36756712	2023
A defect in mitochondrial protein translation influences mitonuclear communication in the heart. Nature communications\| PubMed ID: 36949106	2023
Reduced Mitochondrial Protein Translation Promotes Cardiomyocyte Proliferation and Heart Regeneration. Circulation\| PubMed ID: 37905452	2023
Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects. Nature reviews. Cardiology\| PubMed ID: 37985696	2024
The Impact of miR-155-5p on Myotube Differentiation: Elucidating Molecular Targets in Skeletal Muscle Disorders. International journal of molecular sciences\| PubMed ID: 38339055	2024
Elucidating the crosstalk between endothelial-to-mesenchymal transition (EndoMT) and endothelial autophagy in the pathogenesis of atherosclerosis. Vascular pharmacology\| PubMed ID: 38548093	2024
Corrigendum to "Elucidating the crosstalk between endothelial-to-mesenchymal transition (EndoMT) and endothelial autophagy in the pathogenesis of atherosclerosis" [Vascular Pharmacology 155 ... Vascular pharmacology\| PubMed ID: 38658307	2024
The long noncoding RNA CARDINAL attenuates cardiac hypertrophy by modulating protein translation. The Journal of clinical investigation\| PubMed ID: 38743498	2024
Response by Gao et al to Letter Regarding Article, "Reduced Mitochondrial Protein Translation Promotes Cardiomyocyte Proliferation and Heart Regeneration". Circulation\| PubMed ID: 38768271	2024
Therapeutic Inhibition of Protects Against Cardiac Hypertrophy. Circulation research\| PubMed ID: 38864216	2024
Adapting cytoskeleton-mitochondria patterning with myocyte differentiation by promyogenic PRR33. Cell death and differentiation\| PubMed ID: 39147882	2025
Targeting Liver Epsins Ameliorates Dyslipidemia in Atherosclerosis through Inhibition of Proprotein Convertase Subtilisin/Kexin Type 9-Mediated Low-density Lipoprotein Receptor Degradation. bioRxiv : the preprint server for biology\| PubMed ID: 39253478	2025
Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in Atherosclerosis. bioRxiv : the preprint server for biology\| PubMed ID: 39282400	2024
Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders. Molecular metabolism\| PubMed ID: 39557194	2025
Genetic deletion of 12/15 lipoxygenase delays vascular remodeling and limits cardiorenal dysfunction after pressure overload. Journal of molecular and cellular cardiology plus\| PubMed ID: 39802176	2023
Trbp inhibits cardiac fibrosis through TGF-β pathway-mediated cross-talk between cardiomyocytes and fibroblasts. Clinical science (London, England : 1979)\| PubMed ID: 40067137	2025
Targeting ALDH2 to promote skeletal muscle health: A novel strategy against mitochondrial dysfunction. The Journal of physiology\| PubMed ID: 40684425	2025