Luc Bertrand

Department of Biochemistry and Molecular Biology, University of Miami

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 6	2017
Publication title Cited by 23	2017

Other Publications

Article	Year
The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase. The Journal of biological chemistry\| PubMed ID: 12065600	2002
Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes. European journal of biochemistry\| PubMed ID: 12153571	2002
Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes. European journal of biochemistry\| PubMed ID: 12153572	2002
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis. Current biology : CB\| PubMed ID: 12194824	2002
Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways. Journal of molecular and cellular cardiology\| PubMed ID: 12392881	2002
The stimulation of heart glycolysis by increased workload does not require AMP-activated protein kinase but a wortmannin-sensitive mechanism. FEBS letters\| PubMed ID: 12417335	2002
Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia. The EMBO journal\| PubMed ID: 12970179	2003
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis. The Biochemical journal\| PubMed ID: 15170386	2004
Activation of deoxycytidine kinase by protein kinase inhibitors and okadaic acid in leukemic cells. Biochemical pharmacology\| PubMed ID: 15183121	2004
6-Phosphofructo-2-kinase and fructose-2,6-bisphosphatase in Trypanosomatidae. Molecular characterization, database searches, modelling studies and evolutionary analysis. The FEBS journal\| PubMed ID: 16008555	2005
Myocardial delivery of colloid nanoparticles using ultrasound-targeted microbubble destruction. European heart journal\| PubMed ID: 16166101	2006
Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 16332922	2006
Identification of in vivo phosphorylation sites on human deoxycytidine kinase. Role of Ser-74 in the control of enzyme activity. The Journal of biological chemistry\| PubMed ID: 16361699	2006
H11 kinase prevents myocardial infarction by preemptive preconditioning of the heart. Circulation research\| PubMed ID: 16373598	2006
AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16489105	2006
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase-independent effect on glucokinase translocatio... Diabetes\| PubMed ID: 16567505	2006
[Regulation of energy metabolism by AMPK: a novel therapeutic approach for the treatment of metabolic and cardiovascular diseases]. Medecine sciences : M/S\| PubMed ID: 16597407	2006
Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders. The Journal of physiology\| PubMed ID: 16644802	2006
Optical and EPR spectroscopic studies of demetallation of hemin by L-chain apoferritins. Journal of inorganic biochemistry\| PubMed ID: 16781777	2006
Evaluation of the role of protein kinase Czeta in insulin-induced heart 6-phosphofructo-2-kinase activation. Cellular signalling\| PubMed ID: 16829026	2007
Role of the alpha2-isoform of AMP-activated protein kinase in the metabolic response of the heart to no-flow ischemia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16877552	2006
IGF-I does not prevent myotube atrophy caused by proinflammatory cytokines despite activation of Akt/Foxo and GSK-3beta pathways and inhibition of atrogin-1 mRNA. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 16926385	2007
High-resolution X-ray structures of human apoferritin H-chain mutants correlated with their activity and metal-binding sites. Journal of molecular biology\| PubMed ID: 17070541	2007
Dual cardiac contractile effects of the alpha2-AMPK deletion in low-flow ischemia and reperfusion. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17337600	2007
Creatine enhances differentiation of myogenic C2C12 cells by activating both p38 and Akt/PKB pathways. American journal of physiology. Cell physiology\| PubMed ID: 17652429	2007
The relationship between p38 mitogen-activated protein kinase and AMP-activated protein kinase during myocardial ischemia. Cardiovascular research\| PubMed ID: 17765884	2007
Insulin signalling in the heart. Cardiovascular research\| PubMed ID: 18390897	2008
The conserved N-terminal domain of herpes simplex virus 1 UL24 protein is sufficient to induce the spatial redistribution of nucleolin. The Journal of general virology\| PubMed ID: 18420791	2008
AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol. Biochemical and biophysical research communications\| PubMed ID: 18812163	2008
Comparison between adenoviral and retroviral vectors for the transduction of the thymidine kinase PET reporter gene in rat mesenchymal stem cells. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 18984872	2008
Myocardial injury induced by ultrasound-targeted microbubble destruction: evidence for the contribution of myocardial ischemia. Ultrasound in medicine & biology\| PubMed ID: 19110365	2009
Crucial role for LKB1 to AMPKalpha2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes. Biochimica et biophysica acta\| PubMed ID: 19159696	2009
AMPK: Lessons from transgenic and knockout animals. Frontiers in bioscience (Landmark edition)\| PubMed ID: 19273052	2009
Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity. Biochemical and biophysical research communications\| PubMed ID: 19486896	2009
Conserved residues in the UL24 protein of herpes simplex virus 1 are important for dispersal of the nucleolar protein nucleolin. Journal of virology\| PubMed ID: 19864385	2010
Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 20051528	2010
Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3). The Biochemical journal\| PubMed ID: 20687898	2010
AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure. Cardiovascular research\| PubMed ID: 21285292	2011
Urocortin-induced cardiomyocytes hypertrophy is associated with regulation of the GSK-3β pathway. Heart and vessels\| PubMed ID: 21505854	2012
Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21602475	2011
The ribonucleotide reductase R1 subunits of herpes simplex virus 1 and 2 protect cells against poly(I · C)-induced apoptosis. Journal of virology\| PubMed ID: 21697465	2011
ER stress induces anabolic resistance in muscle cells through PKB-induced blockade of mTORC1. PloS one\| PubMed ID: 21698202	2011
Cardiac and neurological assessment of normothermia/warm blood cardioplegia vs hypothermia/cold crystalloid cardioplegia in pediatric cardiac surgery: insight from a prospective randomized t... European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 21752665	2011
NADPH oxidase activation by hyperglycaemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1. Cardiovascular research\| PubMed ID: 21859816	2011
Urotensin II and urocortin trigger the expression of myostatin, a negative regulator of cardiac growth, in cardiomyocytes. Peptides\| PubMed ID: 22244812	2012
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia. Gut\| PubMed ID: 22271799	2012
AMP-activated protein kinase in the control of cardiac metabolism and remodeling. Current heart failure reports\| PubMed ID: 22767403	2012
Overexpression of AMP-activated protein kinase or protein kinase D prevents lipid-induced insulin resistance in cardiomyocytes. Journal of molecular and cellular cardiology\| PubMed ID: 23159540	2013
Differential regulation of eEF2 and p70S6K by AMPKalpha2 in heart. Biochimica et biophysica acta\| PubMed ID: 23466593	2013
The Onecut transcription factor HNF-6 contributes to proper reorganization of Purkinje cells during postnatal cerebellum development. Molecular and cellular neurosciences\| PubMed ID: 23669529	2013
Connection between cardiac vascular permeability, myocardial edema, and inflammation during sepsis: role of the α1AMP-activated protein kinase isoform. Critical care medicine\| PubMed ID: 23963133	2013
Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells. Cardiovascular research\| PubMed ID: 24104879	2014
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase. Circulation\| PubMed ID: 24190960	2014
Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 24425763	2014
Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway. Biochemical pharmacology\| PubMed ID: 24630930	2014
Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 24742991	2014
A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 24748590	2014
Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKα1. Journal of molecular and cellular cardiology\| PubMed ID: 24805196	2014
AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 25128166	2014
Hypothermic continuous machine perfusion improves metabolic preservation and functional recovery in heart grafts. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 25265884	2015
Metformin: from mechanisms of action to therapies. Cell metabolism\| PubMed ID: 25456737	2014
Dysregulation of Endoplasmic Reticulum Stress and Autophagic Responses by the Antiretroviral Drug Efavirenz. Molecular pharmacology\| PubMed ID: 25987489	2015
Even is better than odd: one fat may conceal another. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26297227	2015
Occludin controls HIV transcription in brain pericytes via regulation of SIRT-1 activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 26601824	2016
Hypothermic continuous machine perfusion enables preservation of energy charge and functional recovery of heart grafts in an ex vivo model of donation following circulatory death. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 26604296	2016
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation. Journal of molecular and cellular cardiology\| PubMed ID: 26772531	2016
Regulation of viral gene expression by the herpes simplex virus 1UL24 protein (HSV-1UL24 inhibits accumulation of viral transcripts). Virology\| PubMed ID: 27214229	2016
Solving the Blood-Brain Barrier Challenge for the Effective Treatment of HIV Replication in the Central Nervous System. Current pharmaceutical design\| PubMed ID: 27464720	2016
O-GlcNAcylation, enemy or ally during cardiac hypertrophy development? Biochimica et biophysica acta\| PubMed ID: 27544701	2016
Fifteen days of 3,200 m simulated hypoxia marginally regulates markers for protein synthesis and degradation in human skeletal muscle. Hypoxia (Auckland, N.Z.)\| PubMed ID: 27800505	2016
Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK. EXS\| PubMed ID: 27812975	2016
AMPK in Cardiovascular Diseases. EXS\| PubMed ID: 27812981	2016
Nuclear respiratory factor 1 and endurance exercise promote human telomere transcription. Science advances\| PubMed ID: 27819056	2016
Antiretroviral Treatment with Efavirenz Disrupts the Blood-Brain Barrier Integrity and Increases Stroke Severity. Scientific reports\| PubMed ID: 28008980	2016
Extracellular vesicles of the blood-brain barrier: Role in the HIV-1 associated amyloid beta pathology. Molecular and cellular neurosciences\| PubMed ID: 28040512	2016
Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart. Scientific reports\| PubMed ID: 28128227	2017