Paul M. W. French

Photonics Group, Imperial College London

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 14	2017

Other Publications

Article	Year
Imaging immune surveillance by T cells and NK cells. Immunological reviews\| PubMed ID: 12445274	2002
Imaging the environment of green fluorescent protein. Biophysical journal\| PubMed ID: 12496126	2002
Fluorescence lifetime imaging of unstained tissues: early results in human breast cancer. The Journal of pathology\| PubMed ID: 12579532	2003
Studying biological tissue with fluorescence lifetime imaging: microscopy, endoscopy, and complex decay profiles. Applied optics\| PubMed ID: 12790450	2003
Time-resolved fluorescence anisotropy imaging applied to live cells. Optics letters\| PubMed ID: 15035478	2004
Holographic optical coherence imaging of rat osteogenic sarcoma tumor spheroids. Applied optics\| PubMed ID: 15449473	2004
Fluorescence imaging of two-photon linear dichroism: cholesterol depletion disrupts molecular orientation in cell membranes. Biophysical journal\| PubMed ID: 15520272	2005
Time-resolved fluorescence microscopy. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology\| PubMed ID: 15616687	2005
Quantitative 3D mapping of fluidic temperatures within microchannel networks using fluorescence lifetime imaging. Analytical chemistry\| PubMed ID: 16579608	2006
Fluorescence lifetime imaging provides enhanced contrast when imaging the phase-sensitive dye di-4-ANEPPDHQ in model membranes and live cells. Biophysical journal\| PubMed ID: 16617080	2006
Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses. The Journal of cell biology\| PubMed ID: 16801390	2006
Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17142745	2006
Tissue characterization using dimensionality reduction and fluorescence imaging. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention\| PubMed ID: 17354820	2006
Rapid hyperspectral fluorescence lifetime imaging. Microscopy research and technique\| PubMed ID: 17366615	2007
Fluorescence-lifetime imaging of DNA-dye interactions within continuous-flow microfluidic systems. Angewandte Chemie (International ed. in English)\| PubMed ID: 17436333	2007
Optical techniques for imaging membrane lipid microdomains in living cells. Seminars in cell & developmental biology\| PubMed ID: 17728161	2007
Fluorescence lifetime imaging by using time-gated data acquisition. Applied optics\| PubMed ID: 17952172	2007
Excitation-resolved hyperspectral fluorescence lifetime imaging using a UV-extended supercontinuum source. Optics letters\| PubMed ID: 18059949	2007
Stimulated emission depletion microscopy with a supercontinuum source and fluorescence lifetime imaging. Optics letters\| PubMed ID: 18197209	2008
Improved sectioning in a slit scanning confocal microscope. Optics letters\| PubMed ID: 18709096	2008
Three-dimensional molecular mapping in a microfluidic mixing device using fluorescence lifetime imaging. Optics letters\| PubMed ID: 18709122	2008
High-speed high-resolution imaging of intercellular immune synapses using optical tweezers. Biophysical journal\| PubMed ID: 18723590	2008
Multiplexed FRET to image multiple signaling events in live cells. Biophysical journal\| PubMed ID: 18757561	2008
Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets. Analytical chemistry\| PubMed ID: 19055421	2009
Live cell linear dichroism imaging reveals extensive membrane ruffling within the docking structure of natural killer cell immune synapses. Biophysical journal\| PubMed ID: 19167281	2009
Fluorescence lifetime optical projection tomography. Journal of biophotonics\| PubMed ID: 19343662	2008
A compact, multidimensional spectrofluorometer exploiting supercontinuum generation. Journal of biophotonics\| PubMed ID: 19343675	2008
High speed unsupervised fluorescence lifetime imaging confocal multiwell plate reader for high content analysis. Journal of biophotonics\| PubMed ID: 19343677	2008
Three-dimensional imaging of Förster resonance energy transfer in heterogeneous turbid media by tomographic fluorescent lifetime imaging. Optics letters\| PubMed ID: 19756100	2009
A fluorescence lifetime imaging scanning confocal endomicroscope. Journal of biophotonics\| PubMed ID: 19787682	2010
Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse. Science signaling\| PubMed ID: 20460647	2010
High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells. Molecular membrane biology\| PubMed ID: 20540668	2010
Differential modes of DNA binding by mismatch uracil DNA glycosylase from Escherichia coli: implications for abasic lesion processing and enzyme communication in the base excision repair pat... Nucleic acids research\| PubMed ID: 21112870	2011
Membrane environment exerts an important influence on rac-mediated activation of phospholipase Cγ2. Molecular and cellular biology\| PubMed ID: 21245382	2011
Wide-field fluorescence lifetime imaging of cancer. Biomedical optics express\| PubMed ID: 21258496	2010
FLIM FRET technology for drug discovery: automated multiwell-plate high-content analysis, multiplexed readouts and application in situ. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 21337485	2011
Adaptive phase compensation for ultracompact laser scanning endomicroscopy. Optics letters\| PubMed ID: 21540976	2011
In vivo fluorescence lifetime optical projection tomography. Biomedical optics express\| PubMed ID: 21559145	2011
In vivo fluorescence lifetime tomography of a FRET probe expressed in mouse. Biomedical optics express\| PubMed ID: 21750768	2011
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. PLoS biology\| PubMed ID: 21931537	2011
Application of ultrafast gold luminescence to measuring the instrument response function for multispectral multiphoton fluorescence lifetime imaging. Optics express\| PubMed ID: 21934746	2011
Quantification of cellular autofluorescence of human skin using multiphoton tomography and fluorescence lifetime imaging in two spectral detection channels. Biomedical optics express\| PubMed ID: 22162820	2011
Förster resonance energy transfer imaging in vivo with approximated radiative transfer equation. Applied optics\| PubMed ID: 22193187	2011
Multiphoton laser microscopy and fluorescence lifetime imaging for the evaluation of the skin. Dermatology research and practice\| PubMed ID: 22203841	2012
In vivo measurements of diffuse reflectance and time-resolved autofluorescence emission spectra of basal cell carcinomas. Journal of biophotonics\| PubMed ID: 22308093	2012
Incorporation of an experimentally determined MTF for spatial frequency filtering and deconvolution during optical projection tomography reconstruction. Optics express\| PubMed ID: 22453413	2012
Multiphoton multispectral fluorescence lifetime tomography for the evaluation of basal cell carcinomas. PloS one\| PubMed ID: 22984428	2012
Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGF. Journal of cell science\| PubMed ID: 22992460	2012
Fluorescence lifetime readouts of Troponin-C-based calcium FRET sensors: a quantitative comparison of CFP and mTFP1 as donor fluorophores. PloS one\| PubMed ID: 23152874	2012
Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation. Journal of biophotonics\| PubMed ID: 23184449	2013
Simultaneous angular multiplexing optical projection tomography at shifted focal planes. Optics letters\| PubMed ID: 23503237	2013
3-D stimulated emission depletion microscopy with programmable aberration correction. Journal of biophotonics\| PubMed ID: 23788459	2014
Multiphoton laser tomography and fluorescence lifetime imaging of melanoma: morphologic features and quantitative data for sensitive and specific non-invasive diagnostics. PloS one\| PubMed ID: 23923016	2013
Rapid global fitting of large fluorescence lifetime imaging microscopy datasets. PloS one\| PubMed ID: 23940626	2013
Fluorescence lifetime spectroscopy of tissue autofluorescence in normal and diseased colon measured ex vivo using a fiber-optic probe. Biomedical optics express\| PubMed ID: 24575345	2014
Introduction: feature issue on optical molecular probes, imaging, and drug delivery. Biomedical optics express\| PubMed ID: 24575356	2014
Analysis of DNA binding and nucleotide flipping kinetics using two-color two-photon fluorescence lifetime imaging microscopy. Analytical chemistry\| PubMed ID: 25303623	2014
Remote focal scanning optical projection tomography with an electrically tunable lens. Biomedical optics express\| PubMed ID: 25360356	2014
Application of time-resolved autofluorescence to label-free in vivo optical mapping of changes in tissue matrix and metabolism associated with myocardial infarction and heart failure. Biomedical optics express\| PubMed ID: 25780727	2015
Mesoscopic in vivo 3-D tracking of sparse cell populations using angular multiplexed optical projection tomography. Biomedical optics express\| PubMed ID: 25909009	2015
Correction Approach for Delta Function Convolution Model Fitting of Fluorescence Decay Data in the Case of a Monoexponential Reference Fluorophore. Journal of fluorescence\| PubMed ID: 26063535	2015
Homo-FRET Based Biosensors and Their Application to Multiplexed Imaging of Signalling Events in Live Cells. International journal of molecular sciences\| PubMed ID: 26133241	2015
Accelerated Optical Projection Tomography Applied to In Vivo Imaging of Zebrafish. PloS one\| PubMed ID: 26308086	2015
Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1. Advances in biological regulation\| PubMed ID: 26482290	2016
Visualising apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time. Journal of biophotonics\| PubMed ID: 26753623	2016
Tunable fibre-coupled multiphoton microscopy with a negative curvature fibre. Journal of biophotonics\| PubMed ID: 26989868	2016
Quantitative in vivo optical tomography of cancer progression & vasculature development in adult zebrafish. Oncotarget\| PubMed ID: 27259259	2016
Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM). Scientific reports\| PubMed ID: 27339025	2016
Imaging of Metabolic Status in 3D Cultures with an Improved AMPK FRET Biosensor for FLIM. Sensors (Basel, Switzerland)\| PubMed ID: 27548185	2016
easySTORM: a robust, lower-cost approach to localisation and TIRF microscopy. Journal of biophotonics\| PubMed ID: 27592533	2016
Corrigendum: Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM). Scientific reports\| PubMed ID: 27654516	2016
Adaptive multiphoton endomicroscopy through a dynamically deformed multicore optical fiber using proximal detection. Optics express\| PubMed ID: 27661887	2016
Plasmonic Nanoprobes for Stimulated Emission Depletion Nanoscopy. ACS nano\| PubMed ID: 27794591	2016
Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET. Scientific reports\| PubMed ID: 28045057	2017