Bernd Schmeck

Institute for Lung Research, Philipps-University Marburg

Affiliated withPhilipps-University Marburg German Center for Lung Research University Medical Center Giessen and Marburg

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 13	2017

Other Publications

Article	Year
Reduction of tumor necrosis factor-alpha (TNF-alpha) related nuclear factor-kappaB (NF-kappaB) translocation but not inhibitor kappa-B (Ikappa-B)-degradation by Rho protein inhibition in hum... Biochemical pharmacology\| PubMed ID: 12213594	2002
Rho protein inactivation induced apoptosis of cultured human endothelial cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 12225960	2002
Adrenomedullin reduces endothelial hyperpermeability. Circulation research\| PubMed ID: 12364390	2002
Rho protein inhibition blocks cyclooxygenase-2 expression by proinflammatory mediators in endothelial cells. Inflammation\| PubMed ID: 12797548	2003
Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae. The Journal of biological chemistry\| PubMed ID: 15215247	2004
Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium. Infection and immunity\| PubMed ID: 15321985	2004
Porphyromonas gingivalis strain-dependent activation of human endothelial cells. Infection and immunity\| PubMed ID: 15385493	2004
Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor. The Journal of biological chemistry\| PubMed ID: 15485852	2004
Neuronal plasticity in persistent perennial allergic rhinitis. Journal of occupational and environmental medicine\| PubMed ID: 15643155	2005
Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae. Circulation research\| PubMed ID: 15653568	2005
Adrenomedullin reduces Staphylococcus aureus alpha-toxin-induced rat ileum microcirculatory damage. Critical care medicine\| PubMed ID: 15818111	2005
Adhesion of Moraxella catarrhalis to human bronchial epithelium characterized by a novel fluorescence-based assay. Medical microbiology and immunology\| PubMed ID: 16059698	2006
Streptococcus pneumoniae R6x induced p38 MAPK and JNK-mediated caspase-dependent apoptosis in human endothelial cells. Thrombosis and haemostasis\| PubMed ID: 16113818	2005
Intracellular bacteria differentially regulated endothelial cytokine release by MAPK-dependent histone modification. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16116170	2005
Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16299055	2006
Mechanisms of Chlamydophila pneumoniae-mediated GM-CSF release in human bronchial epithelial cells. American journal of respiratory cell and molecular biology\| PubMed ID: 16340003	2006
Adrenomedullin treatment abolishes ileal mucosal hypoperfusion induced by Staphylococcus aureus alpha-toxin--an intravital microscopic study on an isolated rat ileum. Critical care medicine\| PubMed ID: 16352964	2005
Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16365441	2006
Moraxella catarrhalis induces inflammatory response of bronchial epithelial cells via MAPK and NF-kappaB activation and histone deacetylase activity reduction. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16399788	2006
Streptococcus pneumoniae induced p38 MAPK- and NF-kappaB-dependent COX-2 expression in human lung epithelium. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16414978	2006
Perturbation of endothelial junction proteins by Staphylococcus aureus alpha-toxin: inhibition of endothelial gap formation by adrenomedullin. Histochemistry and cell biology\| PubMed ID: 16596365	2006
Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia. Critical care medicine\| PubMed ID: 16715037	2006
Lung epithelium as a sentinel and effector system in pneumonia--molecular mechanisms of pathogen recognition and signal transduction. Respiratory research\| PubMed ID: 16827942	2006
Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells. Respiratory research\| PubMed ID: 16834785	2006
Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells. Biochemical pharmacology\| PubMed ID: 16884694	2006
Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication. The Journal of biological chemistry\| PubMed ID: 16984921	2006
Legionella pneumophila-induced PKCalpha-, MAPK-, and NF-kappaB-dependent COX-2 expression in human lung epithelium. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17012371	2007
IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein. Cellular microbiology\| PubMed ID: 17140406	2007
Comparative transcriptional profiling of the lung reveals shared and distinct features of Streptococcus pneumoniae and influenza A virus infection. Immunology\| PubMed ID: 17163962	2007
Adrenomedullin reduces vascular hyperpermeability and improves survival in rat septic shock. Intensive care medicine\| PubMed ID: 17318497	2007
The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells. The Journal of infectious diseases\| PubMed ID: 17471435	2007
Role of platelet-activating factor in pneumolysin-induced acute lung injury. Critical care medicine\| PubMed ID: 17522574	2007
Cell-specific interleukin-15 and interleukin-15 receptor subunit expression and regulation in pneumococcal pneumonia--comparison to chlamydial lung infection. Cytokine\| PubMed ID: 17611121	2007
Proteomic characterization of the whole secretome of Legionella pneumophila and functional analysis of outer membrane vesicles. Infection and immunity\| PubMed ID: 18250176	2008
Simvastatin reduces Chlamydophila pneumoniae-mediated histone modifications and gene expression in cultured human endothelial cells. Circulation research\| PubMed ID: 18309103	2008
Rho-kinase and contractile apparatus proteins in murine airway hyperresponsiveness. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie\| PubMed ID: 18434112	2008
NAIP and Ipaf control Legionella pneumophila replication in human cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18453601	2008
Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18606645	2008
Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18684957	2008
Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia. Critical care medicine\| PubMed ID: 19114881	2009
Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia. Critical care medicine\| PubMed ID: 19114892	2009
Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 19122173	2009
Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20008285	2010
TLR2- and nucleotide-binding oligomerization domain 2-dependent Krüppel-like factor 2 expression downregulates NF-kappa B-related gene expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20525885	2010
Legionella pneumophila induces human beta defensin-3 in pulmonary cells. Respiratory research\| PubMed ID: 20615218	2010
Simvastatin attenuates ventilator-induced lung injury in mice. Critical care (London, England)\| PubMed ID: 20673352	2010
Rac1 regulates the NLRP3 inflammasome which mediates IL-1beta production in Chlamydophila pneumoniae infected human mononuclear cells. PloS one\| PubMed ID: 22276187	2012
TLR9- and Src-dependent expression of Krueppel-like factor 4 controls interleukin-10 expression in pneumonia. The European respiratory journal\| PubMed ID: 22653776	2013
Systems biology and bioinformatics in aging research: a workshop report. Rejuvenation research\| PubMed ID: 22950424	2012
Asthma phenotyping, therapy, and prevention: what can we learn from systems biology? Pediatric research\| PubMed ID: 23314293	2013
MicroRNAs in the lung. Advances in experimental medicine and biology\| PubMed ID: 23377971	2013
Benefits of whole body vibration training in patients hospitalised for COPD exacerbations - a randomized clinical trial. BMC pulmonary medicine\| PubMed ID: 24725369	2014
Malignancy Associated MicroRNA Expression Changes in Canine Mammary Cancer of Different Malignancies. ISRN veterinary science\| PubMed ID: 25002976	2014
Impaired TLR4 and HIF expression in cystic fibrosis bronchial epithelial cells downregulates hemeoxygenase-1 and alters iron homeostasis in vitro. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 25239913	2014
Therapy with plasma purified alpha1-antitrypsin (Prolastin®) induces time-dependent changes in plasma levels of MMP-9 and MPO. PloS one\| PubMed ID: 25635861	2015
Training in Systems Approaches for the Next Generation of Life Scientists and Medical Doctors. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26677180	2016
Systems Medicine for Lung Diseases: Phenotypes and Precision Medicine in Cancer, Infection, and Allergy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26677183	2016
Third-Kind Encounters in Biomedicine: Immunology Meets Mathematics and Informatics to Become Quantitative and Predictive. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26677184	2016
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A. Oncotarget\| PubMed ID: 26760764	2016
MicroRNAs Constitute a Negative Feedback Loop in Streptococcus pneumoniae-Induced Macrophage Activation. The Journal of infectious diseases\| PubMed ID: 26984146	2016
Legionella pneumophila-Derived Outer Membrane Vesicles Promote Bacterial Replication in Macrophages. PLoS pathogens\| PubMed ID: 27105429	2016
Genome-wide Chromatin Profiling of Legionella pneumophila-Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2. The Journal of infectious diseases\| PubMed ID: 27130431	2016
Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation. The Journal of allergy and clinical immunology\| PubMed ID: 27373325	2016
An Interactive Macrophage Signal Transduction Map Facilitates Comparative Analyses of High-Throughput Data. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 28137890	2017