Anthony J. Hickey

Technology Advancement and Commercialization, RTI International

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 10	2017
Publication title Cited by 2	2023

Other Publications

Article	Year
Back to the future: inhaled drug products. Journal of pharmaceutical sciences\| PubMed ID: 23381932	2013
New mechanisms to explain the effects of added lactose fines on the dispersion performance of adhesive mixtures for inhalation. PloS one\| PubMed ID: 24489969	2014
Lipid-based carriers for pulmonary products: preclinical development and case studies in humans. Advanced drug delivery reviews\| PubMed ID: 24819218	2014
Controlled delivery of inhaled therapeutic agents. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 24907604	2014
Scale of health: indices of safety and efficacy in the evolving environment of large biological datasets. Pharmaceutical research\| PubMed ID: 24919930	2014
The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy. Journal of microencapsulation\| PubMed ID: 25090595	2014
Targeting inhaled therapy beyond the lungs. Respiration; international review of thoracic diseases\| PubMed ID: 25277464	2014
In vitro dry powder inhaler formulation performance considerations. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 25497311	2015
Inhaled drug treatment for tuberculosis: Past progress and future prospects. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 26596254	2016
Real-Time Investigation of Tuberculosis Transmission: Developing the Respiratory Aerosol Sampling Chamber (RASC). PloS one\| PubMed ID: 26807816	2016
A dry powder combination of pyrazinoic acid and its n-propyl ester for aerosol administration to animals. International journal of pharmaceutics\| PubMed ID: 27130363	2016
Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis. Pharmaceutical research\| PubMed ID: 27351427	2016
Nanomaterial Drug Products: Manufacturing and Analytical Perspectives. The AAPS journal\| PubMed ID: 27822601	2017
Systems biology for organotypic cell cultures. ALTEX\| PubMed ID: 27846345	2016
Influence of Formulation Factors on the Aerosol Performance of Suspension and Solution Metered Dose Inhalers: A Systematic Approach. The AAPS journal\| PubMed ID: 28593514	2017
Density and Shape Factor Terms in Stokes' Equation for Aerodynamic Behavior of Aerosols. Journal of pharmaceutical sciences\| PubMed ID: 29154770	2018
Reproducibility, sharing and progress in nanomaterial databases. Nature nanotechnology\| PubMed ID: 29209007	2017
Co-suspension delivery technology in pressurized metered-dose inhalers for multi-drug dosing in the treatment of respiratory diseases. Respiratory medicine\| PubMed ID: 29413503	2018
Effects of Formulation Variables on Lung Dosimetry of Albuterol Sulfate Suspension and Beclomethasone Dipropionate Solution Metered Dose Inhalers. AAPS PharmSciTech\| PubMed ID: 29858973	2018
Pharmacokinetics and pharmacodynamics of high doses of inhaled dry powder drugs. International journal of pharmaceutics\| PubMed ID: 30077761	2018
Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis. PloS one\| PubMed ID: 30261007	2018
Exploiting machine learning for end-to-end drug discovery and development. Nature materials\| PubMed ID: 31000803	2019
A Spray-Dried Combination of Capreomycin and CPZEN-45 for Inhaled Tuberculosis Therapy. Journal of pharmaceutical sciences\| PubMed ID: 31152746	2019
Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599. Pharmaceutical research\| PubMed ID: 31321552	2019
Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 31378268	2019
Why Wait? The Case for Treating Tuberculosis with Inhaled Drugs. Pharmaceutical research\| PubMed ID: 31650321	2019
Emerging trends in inhaled drug delivery. Advanced drug delivery reviews\| PubMed ID: 32663488	2020
Synergistic drug combinations and machine learning for drug repurposing in chordoma. Scientific reports\| PubMed ID: 32737414	2020
Designing inhalable metal organic frameworks for pulmonary tuberculosis treatment and theragnostics via spray drying. Chemical communications (Cambridge, England)\| PubMed ID: 33025961	2020
A mechanism-based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID-19 treatment in humans. CPT: pharmacometrics & systems pharmacology\| PubMed ID: 33296558	2021
User-life of ICS/LABA inhaler devices should be considered when prescribed as relievers. The European respiratory journal\| PubMed ID: 33446577	2021
Microfluidic and Organ-on-a-Chip Approaches to Investigate Cellular and Microenvironmental Contributions to Cardiovascular Function and Pathology. Frontiers in bioengineering and biotechnology\| PubMed ID: 33614613	2021
Inhaled antibodies: Quality and performance considerations. Human vaccines & immunotherapeutics\| PubMed ID: 34191682	2022
A technology evaluation of CVT-301 (Inbrija): an inhalable therapy for treatment of Parkinson's disease. Expert opinion on drug delivery\| PubMed ID: 34311641	2021
Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis. ACS infectious diseases\| PubMed ID: 34546724	2021
In vitro-in vivo correlation of pharmaceutical aerosols. Advanced drug delivery reviews\| PubMed ID: 34710531	2021
COVID-19 symptoms are reduced by targeted hydration of the nose, larynx and trachea. Scientific reports\| PubMed ID: 35351914	2022
Nanoformulated Remdesivir with Extremely Low Content of Poly(2-oxazoline)-Based Stabilizer for Aerosol Treatment of COVID-19. Macromolecular bioscience\| PubMed ID: 35526106	2022
Efficacy of inhaled CPZEN-45 in treating tuberculosis in the guinea pig. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 35588549	2022
Optimization and Scale Up of Spray Dried CPZEN-45 Aerosol Powders for Inhaled Tuberculosis Treatment. Pharmaceutical research\| PubMed ID: 36114362	2022
Multiple approaches to repurposing drugs for neuroblastoma. Bioorganic & medicinal chemistry\| PubMed ID: 36208544	2022
Stable nebulization and muco-trapping properties of regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19. Bioengineering & translational medicine\| PubMed ID: 36248234	2022
Spray dried tigecycline dry powder aerosols for the treatment of Nontuberculous mycobacterial pulmonary infections. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 36716525	2023
Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 37120915	2023
Preparation Strategies of the Anti-Mycobacterial Drug Bedaquiline for Intrapulmonary Routes of Administration. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 37242512	2023
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics. Pharmaceutics\| PubMed ID: 37376207	2023
Pharmacokinetic Considerations for Optimizing Inhaled Spray-Dried Pyrazinoic Acid Formulations. Molecular pharmaceutics\| PubMed ID: 37590399	2023