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Customizable Disposable Dosators to Deliver Dry Powder Aerosol Drugs to Mice

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Developing a Disposable Dosator for Preclinical Testing of Dry Powder Inhalers in Small Animal Models (Video) | JoVE

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Medicine

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JoVE Journal Medicine

Disposable Dosators Intended for Dry Powder Delivery to Mice

Developing a Disposable Dosator for Preclinical Testing of Dry Powder Inhalers in Small Animal Models (Video) | JoVE

Customizable Disposable Dosators to Deliver Dry Powder Aerosol Drugs to Mice

DOI:

10.3791/65756-v

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01:45 min

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August 18, 2023

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Sara E. Maloney, Ian E. Stewart, Jeffrey B. Mecham, Mercedes Gonzalez-Juarrero, Bernd Meibohm, Anthony J. Hickey

¹Technology Advancement and Commercialization,RTI International, ²Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology,Colorado State University, ³Department of Pharmaceutical Sciences, College of Pharmacy,University of Tennessee Health Science Center

Tags

Keywords: Disposable Dosators Dry Powder Delivery Mice Inhalational Therapy Mycobacterial Disease Drug-resistant Organisms Dry Powder Inhalers Murine Model Biotherapeutic Moieties Pathogen-specific Solid-state Drug Formulations Device Portability Bolus Metering And Dosing Propellant-free Dispersal In Vivo Testing Spray-dried Powders Dose Control Tamping Uniform Bulk Density Powder Bed

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