Jun-ichi Abe

Department of Cardiology, University of Texas MD Anderson Cancer Center

Affiliated withUniversity of Texas MD Anderson Cancer Center University of Texas MD Anderson Cancer Center

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 20	2017

Other Publications

Article	Year
Activation of mitogen-activated protein kinases and p90 ribosomal S6 kinase in failing human hearts with dilated cardiomyopathy. Cardiovascular research\| PubMed ID: 11744021	2002
Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor. The Journal of biological chemistry\| PubMed ID: 11940581	2002
The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation. The Journal of biological chemistry\| PubMed ID: 12011040	2002
Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression... Circulation research\| PubMed ID: 12065326	2002
Hypoxia and HIF-1alpha stability: another stress-sensing mechanism for Shc. Circulation research\| PubMed ID: 12114314	2002
Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12426206	2002
Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation. The Journal of biological chemistry\| PubMed ID: 12637502	2003
Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases. Journal of pharmacological sciences\| PubMed ID: 12686737	2003
Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells. Circulation research\| PubMed ID: 12919948	2003
Inhibition of tumor necrosis factor-[alpha]-induced SHP-2 phosphatase activity by shear stress: a mechanism to reduce endothelial inflammation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12947019	2003
Preparation and reactivity of a novel disaccharide, glucosyl 1,5-anhydro-D-fructose (1,5-anhydro-3-O-alpha-glucopyranosyl-D-fructose). Carbohydrate research\| PubMed ID: 14553983	2003
Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation. The Journal of biological chemistry\| PubMed ID: 14583600	2004
Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells. The Journal of biological chemistry\| PubMed ID: 14963042	2004
ERK1/2 associates with the c-Met-binding domain of growth factor receptor-bound protein 2 (Grb2)-associated binder-1 (Gab1): role in ERK1/2 and early growth response factor-1 (Egr-1) nuclear... The Journal of biological chemistry\| PubMed ID: 15078886	2004
Activation of big MAP kinase 1 (BMK1/ERK5) inhibits cardiac injury after myocardial ischemia and reperfusion. FEBS letters\| PubMed ID: 15147905	2004
The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional ac... Molecular and cellular biology\| PubMed ID: 15367687	2004
Adenovirus-mediated overexpression of diacylglycerol kinase-zeta inhibits endothelin-1-induced cardiomyocyte hypertrophy. Circulation\| PubMed ID: 15781737	2005
Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation. The Journal of biological chemistry\| PubMed ID: 15840586	2005
Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells. The Journal of biological chemistry\| PubMed ID: 15855164	2005
Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure. Circulation\| PubMed ID: 15867171	2005
BMK1/ERK5 is a novel regulator of angiogenesis by destabilizing hypoxia inducible factor 1alpha. Circulation research\| PubMed ID: 15879308	2005
A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16186489	2005
Cardiac-specific overexpression of diacylglycerol kinase zeta prevents Gq protein-coupled receptor agonist-induced cardiac hypertrophy in transgenic mice. Circulation\| PubMed ID: 16380548	2006
Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium. Circulation\| PubMed ID: 16585392	2006
Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury. Circulation\| PubMed ID: 16717153	2006
Central role of endogenous Toll-like receptor-2 activation in regulating inflammation, reactive oxygen species production, and subsequent neointimal formation after vascular injury. Biochemical and biophysical research communications\| PubMed ID: 16730663	2006
Bone morphogenetic protein (BMP) family, SMAD signaling and Id helix-loop-helix proteins in the vasculature: the continuous mystery of BMPs pleotropic effects. Journal of molecular and cellular cardiology\| PubMed ID: 16762360	2006
Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation. The Journal of biological chemistry\| PubMed ID: 16882656	2006
ERK5 activation inhibits inflammatory responses via peroxisome proliferator-activated receptor delta (PPARdelta) stimulation. The Journal of biological chemistry\| PubMed ID: 16943204	2006
Activation of extracellular signal-regulated kinase 5 reduces cardiac apoptosis and dysfunction via inhibition of a phosphodiesterase 3A/inducible cAMP early repressor feedback loop. Circulation research\| PubMed ID: 17272811	2007
Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart. Circulation research\| PubMed ID: 17332439	2007
Flow antagonizes TNF-alpha signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing. Circulation research\| PubMed ID: 17525369	2007
Neural mechanisms involved in the comprehension of metaphoric and literal sentences: an fMRI study. Brain research\| PubMed ID: 17662699	2007
Role of PKCs and NF-kappaB activation in myocardial inflammation: enemy or ally? Journal of molecular and cellular cardiology\| PubMed ID: 17707396	2007
Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy. Circulation\| PubMed ID: 17967980	2007
Extracellular signal-regulated kinase 5 SUMOylation antagonizes shear stress-induced antiinflammatory response and endothelial nitric oxide synthase expression in endothelial cells. Circulation research\| PubMed ID: 18218985	2008
Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells. Biochemical and biophysical research communications\| PubMed ID: 18358237	2008
Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction. Circulation research\| PubMed ID: 18467627	2008
Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation. Circulation\| PubMed ID: 18541741	2008
Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity. Circulation research\| PubMed ID: 18599872	2008
Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells. Circulation research\| PubMed ID: 19023129	2009
[The effect of L1 word reading system on L2 English word recognition: a comparison of Japanese and Chinese native speakers]. Shinrigaku kenkyu : The Japanese journal of psychology\| PubMed ID: 19069116	2008
NADPH oxidase in vascular injury: a new insight about its regulation and role in T cells. Circulation research\| PubMed ID: 19179667	2009
Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. Nature medicine\| PubMed ID: 19430489	2009
TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19666541	2009
Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy. Circulation research\| PubMed ID: 19797176	2009
Neural substrates of irony comprehension: A functional MRI study. Brain research\| PubMed ID: 19853585	2010
Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart. Circulation research\| PubMed ID: 20075332	2010
SUMO--a post-translational modification with therapeutic potential? Current opinion in pharmacology\| PubMed ID: 20079693	2010
[Is the victim of irony identified by echoic mention?]. Shinrigaku kenkyu : The Japanese journal of psychology\| PubMed ID: 20235473	2010
CCN notch signaling in vascular smooth muscle cells: good or bad? Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20237327	2010
Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20448200	2010
PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5. Blood\| PubMed ID: 20538799	2010
1,5-anhydro-D-fructose and its derivatives: biosynthesis, preparation and potential medical applications. Planta medica\| PubMed ID: 20645241	2010
Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early... FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20724525	2010
Flow shear stress and atherosclerosis: a matter of site specificity. Antioxidants & redox signaling\| PubMed ID: 21050140	2011
Ca2+/calmodulin-stimulated PDE1 regulates the beta-catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells. The FEBS journal\| PubMed ID: 21078118	2010
MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation. Blood\| PubMed ID: 21131586	2011
Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. The Journal of experimental medicine\| PubMed ID: 21173104	2011
p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: a pathogenic mechanism for ischemia-reperfusion injury. Journal of molecular and cellular cardiology\| PubMed ID: 21609719	2011
PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation. The Journal of cell biology\| PubMed ID: 21624955	2011
Fast optical channel recovery in field demonstration of 100-Gbit/s Ethernet over OTN using real-time DSP. Optics express\| PubMed ID: 21747472	2011
Neural processing associated with comprehension of an indirect reply during a scenario reading task. Neuropsychologia\| PubMed ID: 21930137	2011
Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 22076424	2011
p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction. Circulation research\| PubMed ID: 22267842	2012
Does simile comprehension differ from metaphor comprehension? A functional MRI study. Brain and language\| PubMed ID: 22534570	2012
Glucagon-like peptide-1 and its cardiovascular effects. Current atherosclerosis reports\| PubMed ID: 22878937	2012
Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation. International journal of inflammation\| PubMed ID: 22991685	2012
p62 binding to protein kinase C ζ regulates tumor necrosis factor α-induced apoptotic pathway in endothelial cells. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 23023376	2012
Magnetoencephalography evidence for different brain subregions serving two musical cultures. Neuropsychologia\| PubMed ID: 23063935	2012
Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 lig... Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 23202365	2013
A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis. Circulation\| PubMed ID: 23243209	2013
De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis. Circulation research\| PubMed ID: 23381569	2013
Cardiovascular Inflammation 2012: Reactive Oxygen Species, SUMOylation, and Biomarkers in Cardiovascular Inflammation. International journal of inflammation\| PubMed ID: 23555068	2013
Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure. Cardiovascular research\| PubMed ID: 23708738	2013
Cezanne paints inflammation by regulating ubiquitination. Circulation research\| PubMed ID: 23743222	2013
Atheroprone flow activation of the sterol regulatory element binding protein 2 and nod-like receptor protein 3 inflammasome mediates focal atherosclerosis. Circulation\| PubMed ID: 23838164	2013
Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury. Journal of molecular and cellular cardiology\| PubMed ID: 23988739	2013
Insulin activates RSK (p90 ribosomal S6 kinase) to trigger a new negative feedback loop that regulates insulin signaling for glucose metabolism. The Journal of biological chemistry\| PubMed ID: 24036112	2013
Functional modulations in brain activity for the first and second music: a comparison of high- and low-proficiency bimusicals. Neuropsychologia\| PubMed ID: 24365653	2014
Shear stress and atherosclerosis. Molecules and cells\| PubMed ID: 24781409	2014
ERK5 activation in macrophages promotes efferocytosis and inhibits atherosclerosis. Circulation\| PubMed ID: 25001623	2014
Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agen... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25187658	2014
Novel mechanisms of endothelial mechanotransduction. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25301843	2014
¹³⁷Cs concentrations in foliose lichens within Tsukuba-city as a reflection of radioactive fallout from the Fukushima Dai-ichi Nuclear Power Plant accident. Journal of environmental radioactivity\| PubMed ID: 25521042	2015
Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function. The Journal of clinical investigation\| PubMed ID: 25689261	2015
High-mobility group box 1-mediated heat shock protein beta 1 expression attenuates mitochondrial dysfunction and apoptosis. Journal of molecular and cellular cardiology\| PubMed ID: 25736854	2015
PDZK1 prevents neointima formation via suppression of breakpoint cluster region kinase in vascular smooth muscle. PloS one\| PubMed ID: 25886360	2015
Platelet Extracellular Regulated Protein Kinase 5 Is a Redox Switch and Triggers Maladaptive Platelet Responses and Myocardial Infarct Expansion. Circulation\| PubMed ID: 25934838	2015
Axl modulates immune activation of smooth muscle cells in vein graft remodeling. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26276821	2015
The acquisition process of musical tonal schema: implications from connectionist modeling. Frontiers in psychology\| PubMed ID: 26441725	2015
Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events. Antioxidants & redox signaling\| PubMed ID: 26714841	2016
Kinase-SUMO networks in diabetes-mediated cardiovascular disease. Metabolism: clinical and experimental\| PubMed ID: 27085771	2016
Pyroptosis as a Regulated Form of Necrosis: PI+/Annexin V-/High Caspase 1/Low Caspase 9 Activity in Cells = Pyroptosis? Circulation research\| PubMed ID: 27174943	2016
Comparison of Chain-Length Preferences and Glucan Specificities of Isoamylase-Type α-Glucan Debranching Enzymes from Rice, Cyanobacteria, and Bacteria. PloS one\| PubMed ID: 27309534	2016
Multiple Functions of Protein Inhibitor of Activated STAT1 in Regulating Endothelial Cell Proliferation and Inflammation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 27559144	2016
The Future of Onco-Cardiology: We Are Not Just "Side Effect Hunters". Circulation research\| PubMed ID: 27688305	2016
Flow signaling and atherosclerosis. Cellular and molecular life sciences : CMLS\| PubMed ID: 28039525	2017
Sub-cellular localization specific SUMOylation in the heart. Biochimica et biophysica acta\| PubMed ID: 28130202	2017
Coordination of Cellular Localization-Dependent Effects of Sumoylation in Regulating Cardiovascular and Neurological Diseases. Advances in experimental medicine and biology\| PubMed ID: 28197922	2017
STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 28302626	2017