Gaetano Donofrio

Dipartimento di Scienze Medico-Veterinarie, University of Parma

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 14	2017
Publication title Cited by 20	2018

Other Publications

Article	Year
Potential of bovine herpesvirus 4 as a gene delivery vector. Journal of virological methods\| PubMed ID: 11849683	2002
Activation of bovine herpesvirus 4 lytic replication in a non-permissive cell line by overexpression of BoHV-4 immediate early (IE) 2 gene. Journal of virological methods\| PubMed ID: 14738989	2004
Bovine herpesvirus 4 infects differentiated neuronal cells in culture and establish persistent infection upon selection. Journal of neurovirology\| PubMed ID: 15204931	2004
Biologically active bisquaternary ammonium chlorides: physico-chemical properties of long chain amphiphiles and their evaluation as non-viral vectors for gene delivery. Biochimica et biophysica acta\| PubMed ID: 15725392	2005
Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies. Journal of virology\| PubMed ID: 15956578	2005
Potential secondary pathogenic role for bovine herpesvirus 4. Journal of clinical microbiology\| PubMed ID: 16000468	2005
Outcome of bovine herpesvirus 4 infection following direct viral injection in the lateral ventricle of the mouse brain. Microbes and infection\| PubMed ID: 16503181	2006
Bovine herpesvirus 4 based vector interaction with liver cells in vitro and in vivo. Journal of virological methods\| PubMed ID: 16712963	2006
Expression of bovine viral diarrhea virus glycoprotein E2 as a soluble secreted form in a Mammalian cell line. Clinical and vaccine immunology : CVI\| PubMed ID: 16760329	2006
Recombinant bovine herpesvirus 4 (BoHV-4) expressing glycoprotein D of BoHV-1 is immunogenic and elicits serum-neutralizing antibodies against BoHV-1 in a rabbit model. Clinical and vaccine immunology : CVI\| PubMed ID: 16928886	2006
Association between Coxiella burnetii seropositivity and abortion in dairy cattle of Northern Italy. The new microbiologica\| PubMed ID: 17058789	2006
DNA condensation and cell transfection properties of guanidinium calixarenes: dependence on macrocycle lipophilicity, size, and conformation. Journal of the American Chemical Society\| PubMed ID: 17090036	2006
Generation of a transposon insertion mutant library for bovine herpesvirus 4 cloned as a bacterial artificial chromosome by in vitro MuA based DNA transposition system. Journal of virological methods\| PubMed ID: 17182112	2007
First Serbian isolates of bovine herpesvirus 4 (BoHV-4) from a herd with a history of postpartum metritis. The new microbiologica\| PubMed ID: 17319601	2007
Bovine herpesvirus 4 is tropic for bovine endometrial cells and modulates endocrine function. Reproduction (Cambridge, England)\| PubMed ID: 17641100	2007
Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment. Cancer research\| PubMed ID: 17702698	2007
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha ... Blood\| PubMed ID: 17848618	2007
Establishment of a bovine herpesvirus 4 based vector expressing a secreted form of the bovine viral diarrhoea virus structural glycoprotein E2 for immunization purposes. BMC biotechnology\| PubMed ID: 17945009	2007
Assessment of bovine herpesvirus 4 based vector in chicken. Journal of virological methods\| PubMed ID: 18243344	2008
Transduction of the rat brain by Bovine Herpesvirus 4. Genetic vaccines and therapy\| PubMed ID: 18267037	2008
Bacterial infection of endometrial stromal cells influences bovine herpesvirus 4 immediate early gene activation: a new insight into bacterial and viral interaction for uterine disease. Reproduction (Cambridge, England)\| PubMed ID: 18577555	2008
Thermodynamics and biological properties of the aqueous solutions of new glucocationic surfactants. The journal of physical chemistry. B\| PubMed ID: 18616333	2008
Macrocyclic nonviral vectors: high cell transfection efficiency and low toxicity in a lower rim guanidinium calix[4]arene. Organic letters\| PubMed ID: 18722463	2008
Double immunization strategy with a BoHV-4-vectorialized secreted chimeric peptide BVDV-E2/BoHV-1-gD. Vaccine\| PubMed ID: 18812200	2008
Bovine endometrial stromal cells display osteogenic properties. Reproductive biology and endocrinology : RB&E\| PubMed ID: 19087287	2008
Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle. Biology of reproduction\| PubMed ID: 19439727	2009
Isolation and characterization of bovine herpesvirus 4 (BoHV-4) from a cow affected by post partum metritis and cloning of the genome as a bacterial artificial chromosome. Reproductive biology and endocrinology : RB&E\| PubMed ID: 19691825	2009
Cellular targeting of engineered heterologous antigens is a determinant factor for bovine herpesvirus 4-based vaccine vector development. Clinical and vaccine immunology : CVI\| PubMed ID: 19793901	2009
Isolation and characterization of a strain of Lichtheimia corymbifera (ex Absidia corymbifera) from a case of bovine abortion. Reproductive biology and endocrinology : RB&E\| PubMed ID: 19948023	2009
The chemokine IL8 is up-regulated in bovine endometrial stromal cells by the BoHV-4 IE2 gene product, ORF50/Rta: a step ahead toward a mechanism for BoHV-4 induced endometritis. Biology of reproduction\| PubMed ID: 20720165	2010
Integration of bovine herpesvirus 4 genome into cultured persistently infected host cell genome. Virology journal\| PubMed ID: 20854697	2010
Virally and physically transgenized equine adipose-derived stromal cells as a cargo for paracrine secreted factors. BMC cell biology\| PubMed ID: 20863390	2010
Bovine herpesvirus 4 immediate early 2 (Rta) gene is an essential gene and is duplicated in bovine herpesvirus 4 isolate U. Veterinary microbiology\| PubMed ID: 21035279	2011
Bovine herpesvirus 4 based vector as a potential oncolytic-virus for treatment of glioma. Virology journal\| PubMed ID: 21047419	2010
Swine adipose stromal cells loaded with recombinant bovine herpesvirus 4 virions expressing a foreign antigen induce potent humoral immune responses in pigs. Vaccine\| PubMed ID: 21115049	2011
Immunization of knock-out α/β interferon receptor mice against lethal bluetongue infection with a BoHV-4-based vector expressing BTV-8 VP2 antigen. Vaccine\| PubMed ID: 21320537	2011
Herpes simplex virus type 1 thymidine kinase-armed bovine herpesvirus type 4-based vector displays enhanced oncolytic properties in immunocompetent orthotopic syngenic mouse and rat glioma m... Neuro-oncology\| PubMed ID: 22228853	2012
Lower rim guanidinocalix[4]arenes: macrocyclic nonviral vectors for cell transfection. Bioconjugate chemistry\| PubMed ID: 22463059	2012
In vivo imaging of transiently transgenized mice with a bovine interleukin 8 (CXCL8) promoter/luciferase reporter construct. PloS one\| PubMed ID: 22761878	2012
Clinical protection of goats against CpHV-1 induced genital disease with a BoHV-4-based vector expressing CpHV-1 gD. PloS one\| PubMed ID: 23300989	2013
Bovine herpesvirus 4 glycoprotein B is indispensable for lytic replication and irreplaceable by VSVg. BMC veterinary research\| PubMed ID: 23302472	2013
Characterization of caprine herpesvirus 1 (CpHV1) glycoprotein E and glycoprotein I ectodomains expressed in mammalian cells. Veterinary microbiology\| PubMed ID: 23490557	2013
Bovine endometrial stromal cells support tumor necrosis factor alpha-induced bovine herpesvirus type 4 enhanced replication. Biology of reproduction\| PubMed ID: 23515672	2013
Arginine clustering on calix[4]arene macrocycles for improved cell penetration and DNA delivery. Nature communications\| PubMed ID: 23591888	2013
Efficient heterologous antigen gene delivery and expression by a replication-attenuated BoHV-4-based vaccine vector. Vaccine\| PubMed ID: 23830977	2013
Aurora and IKK kinases cooperatively interact to protect multiple myeloma cells from Apo2L/TRAIL. Blood\| PubMed ID: 23974204	2013
Enlightened Mannhemia haemolytica lung inflammation in bovinized mice. Veterinary research\| PubMed ID: 24460618	2014
In vivo image analysis of BoHV-4-based vector in mice. PloS one\| PubMed ID: 24752229	2014
Retinal transduction profiles by high-capacity viral vectors. Gene therapy\| PubMed ID: 24989814	2014
Generation and characterization of the first immortalized alpaca cell line suitable for diagnostic and immunization studies. PloS one\| PubMed ID: 25140515	2014
Interferon gamma-mediated BoHV-4 replication restriction in bovine endometrial stromal cells is host IDO1 gene expression independent and BoHV-4 IE2 gene expression dependent. Biology of reproduction\| PubMed ID: 25273529	2014
Nonviral gene delivery: gemini bispyridinium surfactant-based DNA nanoparticles. The journal of physical chemistry. B\| PubMed ID: 25340646	2014
Cyclodextrin- and calixarene-based polycationic amphiphiles as gene delivery systems: a structure-activity relationship study. Organic & biomolecular chemistry\| PubMed ID: 25474077	2015
Azithromycin inhibits nuclear factor-κB activation during lung inflammation: an in vivo imaging study. Pharmacology research & perspectives\| PubMed ID: 25505605	2014
BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge. PLoS neglected tropical diseases\| PubMed ID: 26086739	2015
In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin. Journal of translational medicine\| PubMed ID: 26239109	2015
BoHV-4 immediate early 1 gene is a dispensable gene and its product is not a bone marrow stromal cell antigen 2 counteracting factor. BMC veterinary research\| PubMed ID: 26307352	2015
The anti-tumoral effect of lenalidomide is increased in vivo by hypoxia-inducible factor (HIF)-1α inhibition in myeloma cells. Haematologica\| PubMed ID: 26659917	2016
Bovine herpesvirus 4-based vector delivering a hybrid rat/human HER-2 oncoantigen efficiently protects mice from autochthonous Her-2(+) mammary cancer. Oncoimmunology\| PubMed ID: 27141335	2016
Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target. Blood\| PubMed ID: 27268090	2016
A chimeric protein comprising the immunogenic domains of Mannheimia haemolytica leukotoxin and outer membrane protein PlpE induces antibodies against leukotoxin and PlpE. Veterinary immunology and immunopathology\| PubMed ID: 27269790	2016
Virus-Mediated Metalloproteinase 1 Induction Revealed by Transcriptome Profiling of Bovine Herpesvirus 4-Infected Bovine Endometrial Stromal Cells. Biology of reproduction\| PubMed ID: 27281703	2016
In vivo monitoring of lung inflammation in CFTR-deficient mice. Journal of translational medicine\| PubMed ID: 27468800	2016
Nonviral gene-delivery by highly fluorinated gemini bispyridinium surfactant-based DNA nanoparticles. Journal of colloid and interface science\| PubMed ID: 27769002	2017
BoHV-4-based vector delivering Ebola virus surface glycoprotein. Journal of translational medicine\| PubMed ID: 27881138	2016
IL21R expressing CD14(+)CD16(+) monocytes expand in multiple myeloma patients leading to increased osteoclasts. Haematologica\| PubMed ID: 28057743	2017
Interleukin 8 haplotypes drive divergent responses in uterine endometrial cells and are associated with somatic cell score in Holstein-Friesian cattle. Veterinary immunology and immunopathology\| PubMed ID: 28166928	2017
Immunization of bighorn sheep against Mannheimia haemolytica with a bovine herpesvirus 1-vectored vaccine. Vaccine\| PubMed ID: 28228321	2017
Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice. Frontiers in immunology\| PubMed ID: 28298912	2017
Bovine herpes virus type 4 alters TNF-α and IL-8 profiles and impairs the survival of bovine endometrial epithelial cells. Reproductive biology\| PubMed ID: 28546031	2017
Assessment and optimization of Theileria parva sporozoite full-length p67 antigen expression in mammalian cells. PLoS neglected tropical diseases\| PubMed ID: 28800590	2017
Coordinated Role of Toll-Like Receptor-3 and Retinoic Acid-Inducible Gene-I in the Innate Response of Bovine Endometrial Cells to Virus. Frontiers in immunology\| PubMed ID: 28878771	2017
Induction of Antihuman C-C Chemokine Receptor Type 5 Antibodies by a Bovine Herpesvirus Type-4 Based Vector. Frontiers in immunology\| PubMed ID: 29118763	2017
Bovine Herpesvirus-4-Based Vector Delivering Peste des Petits Ruminants Virus Hemagglutinin ORF Induces both Neutralizing Antibodies and Cytotoxic T Cell Responses. Frontiers in immunology\| PubMed ID: 29556236	2018