Angelika Eggert

Department of Pediatric Oncology, University Children's Hospital Essen

Affiliated withUniversity Children's Hospital Essen Charité-Universitätsmedizin Berlin, Klinik für Pädiatrie m.S. Onkologie/Hämatologie

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 32	2010
Publication title	2025

Other Publications

Article	Year
Expression of the neurotrophin receptor TrkA down-regulates expression and function of angiogenic stimulators in SH-SY5Y neuroblastoma cells. Cancer research\| PubMed ID: 11912158	2002
Resistance to chemotherapy mediated by TrkB in neuroblastomas. Cancer research\| PubMed ID: 12438236	2002
Apoptosis induction by TRAIL. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12512293	2003
Angiogenic cytokines. Quantitative and functional analysis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12512294	2003
The Phox2B homeobox gene is mutated in sporadic neuroblastomas. Oncogene\| PubMed ID: 15516980	2004
Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas. Oncogene\| PubMed ID: 15637590	2005
Identification of dynamic proteome changes upon ligand activation of Trk-receptors using two-dimensional fluorescence difference gel electrophoresis and mass spectrometry. Molecular & cellular proteomics : MCP\| PubMed ID: 15654083	2005
Biological effects of TrkA and TrkB receptor signaling in neuroblastoma. Cancer letters\| PubMed ID: 15921851	2005
Application of microarray-based technology to neuroblastoma. Cancer letters\| PubMed ID: 15951106	2005
Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma. Oncogene\| PubMed ID: 16007192	2005
The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness. Carcinogenesis\| PubMed ID: 16051641	2005
Phox2B mutations and the Delta-Notch pathway in neuroblastoma. Cancer letters\| PubMed ID: 16084642	2005
Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling. Oncogene\| PubMed ID: 16103881	2005
VEGF plasma levels in non-ruptured intracranial aneurysms. Neurosurgical review\| PubMed ID: 16133453	2006
Vascular endothelial growth factor plasma levels are significantly elevated in patients with cerebral arteriovenous malformations. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 16388189	2006
Identification of a set of seven genes for the monitoring of minimal residual disease in pediatric acute myeloid leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16638849	2006
Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes. Genome biology\| PubMed ID: 16989664	2006
High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors. International journal of cancer. Journal international du cancer\| PubMed ID: 17096344	2007
Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17332289	2007
Fractalkine (CX3CL1)- and interleukin-2-enriched neuroblastoma microenvironment induces eradication of metastases mediated by T cells and natural killer cells. Cancer research\| PubMed ID: 17332365	2007
The mutagenic potential of non-homologous end joining in the absence of the NHEJ core factors Ku70/80, DNA-PKcs and XRCC4-LigIV. Mutagenesis\| PubMed ID: 17347130	2007
ArrayCGH-based classification of neuroblastoma into genomic subgroups. Genes, chromosomes & cancer\| PubMed ID: 17823929	2007
MYCN regulates oncogenic MicroRNAs in neuroblastoma. International journal of cancer. Journal international du cancer\| PubMed ID: 17943719	2008
Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomics. International journal of cancer. Journal international du cancer\| PubMed ID: 17973261	2008
Neurotrophin receptor expression in human primary retinoblastomas and retinoblastoma cell lines. Pediatric blood & cancer\| PubMed ID: 17973327	2008
Neuroblastoma: biology, prognosis, and treatment. Pediatric clinics of North America\| PubMed ID: 18242317	2008
Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18281552	2008
Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 18294840	2008
CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23. BMC cancer\| PubMed ID: 18559103	2008
Photodynamic therapy in retinoblastoma: effects of verteporfin on retinoblastoma cell lines. Investigative ophthalmology & visual science\| PubMed ID: 18579764	2008
Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells. Cancer letters\| PubMed ID: 18620802	2008
MicroRNAs in the pathogenesis of neuroblastoma. Cancer letters\| PubMed ID: 18639376	2009
Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cells. DNA repair\| PubMed ID: 18678285	2008
The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo. International journal of cancer. Journal international du cancer\| PubMed ID: 19142969	2009
Overall genomic pattern is a predictor of outcome in neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19171713	2009
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy. Cancer research\| PubMed ID: 19223552	2009
Reanalysis of neuroblastoma expression profiling data using improved methodology and extended follow-up increases validity of outcome prediction. Cancer letters\| PubMed ID: 19349112	2009
Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compounds. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19435837	2009
Xenogeneic immunization with human tyrosine hydroxylase DNA vaccines suppresses growth of established neuroblastoma. Molecular cancer therapeutics\| PubMed ID: 19671753	2009
Neuroblastoma: biology, prognosis, and treatment. Hematology/oncology clinics of North America\| PubMed ID: 20113896	2010
IL-2-driven regulation of NK cell receptors with regard to the distribution of CD16+ and CD16- subpopulations and in vivo influence after haploidentical NK cell infusion. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 20145545	2010
Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20179214	2010
Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20406844	2010
Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma. Nucleic acids research\| PubMed ID: 20466808	2010
Accurate prediction of neuroblastoma outcome based on miRNA expression profiles. International journal of cancer. Journal international du cancer\| PubMed ID: 20473924	2010
Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20719933	2010
The quassinoid derivative NBT-272 targets both the AKT and ERK signaling pathways in embryonal tumors. Molecular cancer therapeutics\| PubMed ID: 20889731	2010
A small kiss of death for cancer. Nature medicine\| PubMed ID: 20930746	2010
Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21169242	2011
Regulatory BCL2 promoter polymorphism (-938C>A) is associated with adverse outcome in patients with prostate carcinoma. International journal of cancer. Journal international du cancer\| PubMed ID: 21207420	2011
High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21632861	2011
Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas. International journal of cancer. Journal international du cancer\| PubMed ID: 21796619	2011
Progress in treatment and risk stratification of neuroblastoma: impact on future clinical and basic research. Seminars in cancer biology\| PubMed ID: 21798350	2011
miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22031095	2011
The metallophosphodiesterase Mpped2 impairs tumorigenesis in neuroblastoma. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22262177	2012
[In Process Citation]. Krankenpflege. Soins infirmiers\| PubMed ID: 22338269	2012
Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 27479119	2016
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions. Nature communications\| PubMed ID: 34815394	2021