Shaun R. Brinsmade

Department of Biology, Georgetown University

Affiliated withGeorgetown University

Research Area

Biochemistry Genetics

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 1	2017
Publication title Cited by 4	2019

Other Publications

Article	Year
The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state. Biochemistry\| PubMed ID: 12564922	2003
The eutD gene of Salmonella enterica encodes a protein with phosphotransacetylase enzyme activity. Journal of bacteriology\| PubMed ID: 14996820	2004
Minimal functions and physiological conditions required for growth of salmonella enterica on ethanolamine in the absence of the metabolosome. Journal of bacteriology\| PubMed ID: 16291677	2005
Mutation of phosphotransacetylase but not isocitrate lyase reduces the virulence of Salmonella enterica serovar Typhimurium in mice. Infection and immunity\| PubMed ID: 16552088	2006
In vivo and in vitro analyses of single-amino acid variants of the Salmonella enterica phosphotransacetylase enzyme provide insights into the function of its N-terminal domain. The Journal of biological chemistry\| PubMed ID: 17339319	2007
Regulation of CodY activity through modulation of intracellular branched-chain amino acid pools. Journal of bacteriology\| PubMed ID: 20935095	2010
Involvement of protein acetylation in glucose-induced transcription of a stress-responsive promoter. Molecular microbiology\| PubMed ID: 21696463	2011
Dissecting complex metabolic integration provides direct genetic evidence for CodY activation by guanine nucleotides. Journal of bacteriology\| PubMed ID: 21856856	2011
GTP dysregulation in Bacillus subtilis cells lacking (p)ppGpp results in phenotypic amino acid auxotrophy and failure to adapt to nutrient downshift and regulate biosynthesis genes. Journal of bacteriology\| PubMed ID: 24163341	2014
Hierarchical expression of genes controlled by the Bacillus subtilis global regulatory protein CodY. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24843172	2014
Genome Sequence of the Clinical Isolate Staphylococcus aureus subsp. aureus Strain UAMS-1. Genome announcements\| PubMed ID: 25676774	2015
Intermediate Levels of Bacillus subtilis CodY Activity Are Required for Derepression of the Branched-Chain Amino Acid Permease, BraB. PLoS genetics\| PubMed ID: 26473603	2015
A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus. Molecular microbiology\| PubMed ID: 27116338	2016
CodY, a master integrator of metabolism and virulence in Gram-positive bacteria. Current genetics\| PubMed ID: 27744611	2016
Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus aureus. Journal of bacteriology\| PubMed ID: 29378891	2018
Guanine limitation results in CodY-dependent and -independent alteration of physiology and gene expression. Journal of bacteriology\| PubMed ID: 29712876	2018