Geert Berx

Department of Biomedical Molecular Biology, Ghent University

Affiliated withGhent University VIB Cancer Research Institute Ghent (CRIG)

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2017

Other Publications

Article	Year
Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells. Oncogene\| PubMed ID: 12203117	2002
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal ... Genes, chromosomes & cancer\| PubMed ID: 12203774	2002
Identification of excretory-secretory products of larval and adult Ostertagia ostertagi by immunoscreening of cDNA libraries. Molecular and biochemical parasitology\| PubMed ID: 12615319	2003
Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells. Oncogene\| PubMed ID: 14562048	2003
Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons. BMC genomics\| PubMed ID: 15018647	2004
GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3. Nucleic acids research\| PubMed ID: 15302915	2004
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene\| PubMed ID: 15674322	2005
Unraveling signalling cascades for the Snail family of transcription factors. Cellular signalling\| PubMed ID: 15683729	2005
The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. Cancer research\| PubMed ID: 16024625	2005
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions. Nucleic acids research\| PubMed ID: 16314317	2005
Snail in the frame of malignant tumor recurrence. Breast cancer research : BCR\| PubMed ID: 16834762	2006
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology\| PubMed ID: 16952552	2006
E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion. Cancer research\| PubMed ID: 17047063	2006
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail. Molecular and cellular biology\| PubMed ID: 17060462	2007
Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. Molecular biology of the cell\| PubMed ID: 17855508	2007
Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clinical & experimental metastasis\| PubMed ID: 17978854	2007
Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expressio... The American journal of pathology\| PubMed ID: 18385519	2008
A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes. PloS one\| PubMed ID: 18493581	2008
Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front. Histochemistry and cell biology\| PubMed ID: 18648847	2008
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells. Nucleic acids research\| PubMed ID: 19279185	2009
Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair. Breast cancer research : BCR\| PubMed ID: 19664188	2009
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes. Blood\| PubMed ID: 19726720	2009
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. PLoS genetics\| PubMed ID: 20090939	2010
Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma. The American journal of pathology\| PubMed ID: 20150431	2010
Module network inference from a cancer gene expression data set identifies microRNA regulated modules. PloS one\| PubMed ID: 20418949	2010
Involvement of members of the cadherin superfamily in cancer. Cold Spring Harbor perspectives in biology\| PubMed ID: 20457567	2009
Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression. Breast cancer research : BCR\| PubMed ID: 20594364	2010
The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. Blood\| PubMed ID: 21355089	2011
Identification of putative cancer genes through data integration and comparative genomics between plants and humans. Cellular and molecular life sciences : CMLS\| PubMed ID: 22218400	2012
Evolutionary functional analysis and molecular regulation of the ZEB transcription factors. Cellular and molecular life sciences : CMLS\| PubMed ID: 22349261	2012
Concepts of metastasis in flux: the stromal progression model. Seminars in cancer biology\| PubMed ID: 22374376	2012
Gene expression profiling to dissect the complexity of cancer biology: pitfalls and promise. Seminars in cancer biology\| PubMed ID: 22459768	2012
Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron\| PubMed ID: 23312517	2013
Regulatory networks defining EMT during cancer initiation and progression. Nature reviews. Cancer\| PubMed ID: 23344542	2013
Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression. Biochemical and biophysical research communications\| PubMed ID: 23376074	2013
Cadherins and epithelial-to-mesenchymal transition. Progress in molecular biology and translational science\| PubMed ID: 23481201	2013
ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins. Cellular and molecular life sciences : CMLS\| PubMed ID: 24573695	2014
Strategies for immortalization of primary hepatocytes. Journal of hepatology\| PubMed ID: 24911463	2014
Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability. Neoplasia (New York, N.Y.)\| PubMed ID: 25246271	2014
Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity. Frontiers in oncology\| PubMed ID: 25538895	2014
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling. Nature communications\| PubMed ID: 25565005	2015
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium. The EMBO journal\| PubMed ID: 25759216	2015
Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells. Biomaterials\| PubMed ID: 25907048	2015
NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest. BMC cancer\| PubMed ID: 25958384	2015
Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection. The Journal of experimental medicine\| PubMed ID: 26503444	2015
Development and characterization of a new human hepatic cell line. EXCLI journal\| PubMed ID: 26869867	2015
LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19. Haematologica\| PubMed ID: 26969084	2016
Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell reports\| PubMed ID: 27050509	2016
The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2. The Journal of experimental medicine\| PubMed ID: 27185854	2016
Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells. Cancer research\| PubMed ID: 27221703	2016
p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification. PLoS genetics\| PubMed ID: 27556156	2016
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation. The Journal of investigative dermatology\| PubMed ID: 27725202	2017
Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells. Stem cells (Dayton, Ohio)\| PubMed ID: 27739137	2017
Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia. Blood\| PubMed ID: 28069602	2017
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research. Nature methods\| PubMed ID: 28245209	2017