Jorge Busciglio

Department of Neurobiology and Behavior, University of California, Irvine

Affiliated withUniversity of California, Irvine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2010

Other Publications

Article	Year
Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome. Neuron\| PubMed ID: 11879646	2002
Fast axonal transport misregulation and Alzheimer's disease. Neuromolecular medicine\| PubMed ID: 12428805	2002
Aberrant activation of focal adhesion proteins mediates fibrillar amyloid beta-induced neuronal dystrophy. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12533609	2003
GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience\| PubMed ID: 12711349	2003
Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12805290	2003
Live discussion. From here to there: AbetaPP as an axonal transport receptor--how could this explain neurodegeneration in AD. 15 July 2002. Journal of Alzheimer's disease : JAD\| PubMed ID: 14765517	2003
Deposition of amyloid fibrils promotes cell-surface accumulation of amyloid beta precursor protein. Neurobiology of disease\| PubMed ID: 15262274	2004
ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15745955	2005
Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16738244	2006
Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16775141	2006
Beta-amyloid, oxidative stress and down syndrome. Current Alzheimer research\| PubMed ID: 17168651	2006
NAP and ADNF-9 protect normal and Down's syndrome cortical neurons from oxidative damage and apoptosis. Current pharmaceutical design\| PubMed ID: 17430172	2007
Tau isoform expression and regulation in human cortical neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 18263702	2008
Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease. Free radical biology & medicine\| PubMed ID: 18423383	2008
A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19339596	2009
A role for thrombospondin-1 deficits in astrocyte-mediated spine and synaptic pathology in Down's syndrome. PloS one\| PubMed ID: 21152035	2010
Mitochondrial dysfunction and Down's syndrome: is there a role for coenzyme Q(10) ? BioFactors (Oxford, England)\| PubMed ID: 22009852	2011