Barry J. Grant

Department of Computational Medicine and Bioinformatics, University of Michigan Medical School

Affiliated withUniversity of Michigan Medical School

Research Area

Biography

Barry J. Grant has not added Biography.
If you are Barry J. Grant and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2017

Other Publications

Article	Year
LeuT conformational sampling utilizing accelerated molecular dynamics and principal component analysis. Biophysical journal\| PubMed ID: 22828348	2012
Domain-opening and dynamic coupling in the α-subunit of heterotrimeric G proteins. Biophysical journal\| PubMed ID: 23870276	2013
sgTarget: a target selection resource for structural genomics. Nucleic acids research\| PubMed ID: 16844998	2006
Bio3d: an R package for the comparative analysis of protein structures. Bioinformatics (Oxford, England)\| PubMed ID: 16940322	2006
Multivariate analysis of conserved sequence-structure relationships in kinesins: coupling of the active site and a tubulin-binding sub-domain. Journal of molecular biology\| PubMed ID: 17399740	2007
The 2006 automated function prediction meeting. BMC bioinformatics\| PubMed ID: 17570143	2007
Mapping the nucleotide and isoform-dependent structural and dynamical features of Ras proteins. Structure (London, England : 1993)\| PubMed ID: 18547521	2008
Ras conformational switching: simulating nucleotide-dependent conformational transitions with accelerated molecular dynamics. PLoS computational biology\| PubMed ID: 19300489	2009
Large conformational changes in proteins: signaling and other functions. Current opinion in structural biology\| PubMed ID: 20060708	2010
The distinct conformational dynamics of K-Ras and H-Ras A59G. PLoS computational biology\| PubMed ID: 20838576	2010
Conformational selection in G-proteins: lessons from Ras and Rho. Biophysical journal\| PubMed ID: 21112273	2010
Accessing a hidden conformation of the maltose binding protein using accelerated molecular dynamics. PLoS computational biology\| PubMed ID: 21533070	2011
Large-scale conformational changes of Trypanosoma cruzi proline racemase predicted by accelerated molecular dynamics simulation. PLoS computational biology\| PubMed ID: 22022240	2011
Novel allosteric sites on Ras for lead generation. PloS one\| PubMed ID: 22046245	2011
Induced fit or conformational selection? The role of the semi-closed state in the maltose binding protein. Biochemistry\| PubMed ID: 22050600	2011
Electrostatically biased binding of kinesin to microtubules. PLoS biology\| PubMed ID: 22140358	2011
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22645359	2012
Identification of potential small molecule binding pockets on Rho family GTPases. PloS one\| PubMed ID: 22815826	2012
Calcium binding and allosteric signaling mechanisms for the sarcoplasmic reticulum Ca²+ ATPase. Protein science : a publication of the Protein Society\| PubMed ID: 22821874	2012
Mapping the structural and dynamical features of kinesin motor domains. PLoS computational biology\| PubMed ID: 24244137	2013
Novel procedure for thermal equilibration in molecular dynamics simulation. Molecular simulation\| PubMed ID: 25125797	2009
Kinesin-5 allosteric inhibitors uncouple the dynamics of nucleotide, microtubule, and neck-linker binding sites. Biophysical journal\| PubMed ID: 25418105	2014
Integrating protein structural dynamics and evolutionary analysis with Bio3D. BMC bioinformatics\| PubMed ID: 25491031	2014
Enrichment of druggable conformations from apo protein structures using cosolvent-accelerated molecular dynamics. Biology\| PubMed ID: 25906084	2015
Mapping the Processivity Determinants of the Kinesin-3 Motor Domain. Biophysical journal\| PubMed ID: 26488644	2015
Dynamic Coupling and Allosteric Networks in the α Subunit of Heterotrimeric G Proteins. The Journal of biological chemistry\| PubMed ID: 26703464	2016
Rapid Characterization of Allosteric Networks with Ensemble Normal Mode Analysis. The journal of physical chemistry. B\| PubMed ID: 27056373	2016
Online interactive analysis of protein structure ensembles with Bio3D-web. Bioinformatics (Oxford, England)\| PubMed ID: 27423893	2016
Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies. Cell chemical biology\| PubMed ID: 28042045	2017
Computational and biochemical characterization of two partially overlapping interfaces and multiple weak-affinity K-Ras dimers. Scientific reports\| PubMed ID: 28067274	2017
Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. Molecular cell\| PubMed ID: 28306507	2017