Nancy Kedersha

Division of Rheumatology, Brigham and Women's Hospital

Affiliated withBrigham and Women's Hospital Harvard Medical School

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 33	2017

Other Publications

Article	Year
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Molecular biology of the cell\| PubMed ID: 11809833	2002
Stressful initiations. Journal of cell science\| PubMed ID: 12140254	2002
Sendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosis. The EMBO journal\| PubMed ID: 12356730	2002
Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation. Cell stress & chaperones\| PubMed ID: 12380690	2002
Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1. The Journal of experimental medicine\| PubMed ID: 12885872	2003
U1 snRNP-dependent function of TIAR in the regulation of alternative RNA processing of the human calcitonin/CGRP pre-mRNA. Molecular and cellular biology\| PubMed ID: 12917321	2003
Vaults bind directly to microtubules via their caps and not their barrels. Cell motility and the cytoskeleton\| PubMed ID: 14584025	2003
Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death. European journal of immunology\| PubMed ID: 14635036	2003
Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14769925	2004
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. The EMBO journal\| PubMed ID: 15014438	2004
Post-transcriptional regulation of proinflammatory proteins. Journal of leukocyte biology\| PubMed ID: 15075353	2004
FAST is a BCL-X(L)-associated mitochondrial protein. Biochemical and biophysical research communications\| PubMed ID: 15110758	2004
Stress granule assembly is mediated by prion-like aggregation of TIA-1. Molecular biology of the cell\| PubMed ID: 15371533	2004
FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression. Molecular and cellular biology\| PubMed ID: 15572676	2004
Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth. Molecular biology of the cell\| PubMed ID: 15659642	2005
Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arse... The Journal of biological chemistry\| PubMed ID: 15684421	2005
Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation. Molecular biology of the cell\| PubMed ID: 15930128	2005
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. The Journal of cell biology\| PubMed ID: 15967811	2005
RNA granules. The Journal of cell biology\| PubMed ID: 16520386	2006
Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. The Journal of biological chemistry\| PubMed ID: 16951406	2006
Polysome-bound endonuclease PMR1 is targeted to stress granules via stress-specific binding to TIA-1. Molecular and cellular biology\| PubMed ID: 16982678	2006
On again, off again: the SRC-3 transcriptional coactivator moonlights as a translational corepressor. Molecular cell\| PubMed ID: 17386257	2007
Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17592127	2007
Ribosomal slowdown mediates translational arrest during cellular division. Molecular and cellular biology\| PubMed ID: 17664278	2007
Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR. Molecular and cellular biology\| PubMed ID: 17682065	2007
T-cell intracellular antigen-1 (TIA-1)-induced translational silencing promotes the decay of selected mRNAs. The Journal of biological chemistry\| PubMed ID: 17711853	2007
Mammalian stress granules and processing bodies. Methods in enzymology\| PubMed ID: 17923231	2007
Stress granules: the Tao of RNA triage. Trends in biochemical sciences\| PubMed ID: 18291657	2008
Autoantibodies to the translational suppressors T cell intracytoplasmic antigen 1 and T cell intracytoplasmic antigen 1-related protein in patients with rheumatic diseases: increased prevale... Arthritis and rheumatism\| PubMed ID: 18438838	2008
A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nature cell biology\| PubMed ID: 18794846	2008
Real-time and quantitative imaging of mammalian stress granules and processing bodies. Methods in enzymology\| PubMed ID: 19111193	2008
Identification of a cytoplasmic complex that adds a cap onto 5'-monophosphate RNA. Molecular and cellular biology\| PubMed ID: 19223470	2009
RNA granules: post-transcriptional and epigenetic modulators of gene expression. Nature reviews. Molecular cell biology\| PubMed ID: 19461665	2009
Stress granules. Current biology : CB\| PubMed ID: 19467203	2009
Metazoan stress granule assembly is mediated by P-eIF2alpha-dependent and -independent mechanisms. RNA (New York, N.Y.)\| PubMed ID: 19661161	2009
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. The Journal of biological chemistry\| PubMed ID: 20129916	2010
Regulation of translation by stress granules and processing bodies. Progress in molecular biology and translational science\| PubMed ID: 20374741	2009
Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration. Biochemical and biophysical research communications\| PubMed ID: 20869947	2010
Visualization of single mRNAs reveals temporal association of proteins with microRNA-regulated mRNA. Nucleic acids research\| PubMed ID: 21653551	2011
Stress puts TIA on TOP. Genes & development\| PubMed ID: 22012617	2011
Relationship of GW/P-bodies with stress granules. Advances in experimental medicine and biology\| PubMed ID: 23224972	2013
Stress granules and cell signaling: more than just a passing phase? Trends in biochemical sciences\| PubMed ID: 24029419	2013
Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue. Neurogenetics\| PubMed ID: 24659297	2014
Activation of stress response pathways promotes formation of antiviral granules and restricts virus replication. Molecular and cellular biology\| PubMed ID: 24662051	2014
Stress granules, P-bodies and cancer. Biochimica et biophysica acta\| PubMed ID: 25482014	2015
Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation. PLoS pathogens\| PubMed ID: 25658430	2015
Stress granules regulate double-stranded RNA-dependent protein kinase activation through a complex containing G3BP1 and Caprin1. mBio\| PubMed ID: 25784705	2015
Methods for the characterization of stress granules in virus infected cells. Methods (San Diego, Calif.)\| PubMed ID: 25896634	2015
G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits. The Journal of cell biology\| PubMed ID: 27022092	2016
Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation. Oncotarget\| PubMed ID: 27083003	2016
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression. Nucleic acids research\| PubMed ID: 27174937	2016
Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation. Biochimica et biophysica acta\| PubMed ID: 27240544	2016
Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. Journal of virology\| PubMed ID: 27252530	2016
Stress-specific differences in assembly and composition of stress granules and related foci. Journal of cell science\| PubMed ID: 28096475	2017
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics. Molecular cell\| PubMed ID: 28306503	2017