glycoproteomics-extracellular-matrix-method-for-intact-glycopeptide

Glycoproteomics of the Extracellular Matrix: A Method for Intact Glycopeptide Analysis Using Mass Spectrometry

Fibrosis is a hallmark of many cardiovascular diseases and is associated with the exacerbated secretion and deposition of the extracellular matrix (ECM). ...

King's College London

Abdominal aortic aneurysms constitute a degenerative process in the aortic wall. Both the miR-29 and miR-15 families have been implicated in regulating the vascular extracellular matrix.

Role of miR-195 in aortic aneurysmal disease.

Extracellular matrix remodelling has been implicated in a number of vascular conditions, including venous hypertension and varicose veins. However, to date, no systematic analysis of matrix remodelling in human veins has been performed.

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

Myocardial fibrosis is a feature of many cardiac diseases. We used proteomics to profile glycoproteins in the human cardiac extracellular matrix (ECM).

Article	Year
Role of miR-195 in aortic aneurysmal disease. Circulation research\| PubMed ID: 25201911	2014
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins. Cardiovascular research\| PubMed ID: 27068509	2016
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. Circulation\| PubMed ID: 27559042	2016

Marika Fava

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