Martin Marsala

Neuroregeneration Laboratory, University of California, San Diego

Affiliated withUniversity of California, San Diego Slovak Academy of Sciences

Research Area

Biography

Martin Marsala has not added Biography.
If you are Martin Marsala and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2017

Other Publications

Article	Year
Electroporation for direct spinal gene transfer in rats. Neuroscience letters\| PubMed ID: 11750982	2002
The effects of OP-1206 alpha-CD on walking dysfunction in the rat neuropathic intermittent claudication model. Anesthesia and analgesia\| PubMed ID: 12032022	2002
Neuropathic pain is associated with alterations of nitric oxide synthase immunoreactivity and catalytic activity in dorsal root ganglia and spinal dorsal horn. Brain research bulletin\| PubMed ID: 12127013	2002
The regional distribution of nitric oxide synthase activity in the spinal cord of the dog. Brain research bulletin\| PubMed ID: 12127014	2002
The case for the bulbospinal respiratory nitric oxide synthase-immunoreactive pathway in the dog. Experimental neurology\| PubMed ID: 12429216	2002
Localization of N-type Ca2+ channels in the rat spinal cord following chronic constrictive nerve injury. Experimental brain research\| PubMed ID: 12444477	2002
Peripheral axotomy affects nicotinamide adenine dinucleotide phosphate diaphorase and nitric oxide synthases in the spinal cord of the rabbit. Journal of neuroscience research\| PubMed ID: 12503094	2003
Spinal amino acid release and repeated withdrawal in spinal morphine tolerant rats. British journal of pharmacology\| PubMed ID: 12598423	2003
Neuraxial morphine may trigger transient motor dysfunction after a noninjurious interval of spinal cord ischemia: a clinical and experimental study. Anesthesiology\| PubMed ID: 12657847	2003
Spinal adenosine agonist reduces c-fos and astrocyte activation in dorsal horn of rats with adjuvant-induced arthritis. Neuroscience letters\| PubMed ID: 12668251	2003
Localization and distribution patterns of nicotinamide adenine dinucleotide phosphate diaphorase exhibiting axons in the white matter of the spinal cord of the rabbit. Cellular and molecular neurobiology\| PubMed ID: 12701884	2003
Effects of orally administered OP-1206 alpha-CD with loxoprofen-Na on walking dysfunction in the rat neuropathic intermittent claudication model. Prostaglandins, leukotrienes, and essential fatty acids\| PubMed ID: 12907137	2003
Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing. Journal of neurochemistry\| PubMed ID: 12950462	2003
Spinal heat shock protein (70) expression: effect of spinal ischemia, hyperthermia (42 degrees C)/hypothermia (27 degrees C), NMDA receptor activation and potassium evoked depolarization on ... Neurochemistry international\| PubMed ID: 12963088	2004
Effects of OP-1206 alpha-CD on walking dysfunction in the rat neuropathic intermittent claudication model: comparison with nifedipine, ticlopidine and cilostazol. Prostaglandins & other lipid mediators\| PubMed ID: 14518565	2003
Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat. Journal of neuroscience research\| PubMed ID: 14598299	2003
Mediators of ischemic preconditioning identified by microarray analysis of rat spinal cord. Experimental neurology\| PubMed ID: 14697320	2004
Characterization of spinal HSP72 induction and development of ischemic tolerance after spinal ischemia in rats. Experimental neurology\| PubMed ID: 14697321	2004
The effect of cauda equina constriction on nitric oxide synthase activity. Neurochemical research\| PubMed ID: 15002741	2004
Premotor nitric oxide synthase immunoreactive pathway connecting lumbar segments with the ventral motor nucleus of the cervical enlargement in the dog. Journal of chemical neuroanatomy\| PubMed ID: 15036362	2004
Loop dialysis catheter: a technology for chronic spinal dialysis in a freely moving rat. Methods in molecular medicine\| PubMed ID: 15131332	2004
Region-specific cell grafting into cervical and lumbar spinal cord in rat: a qualitative and quantitative stereological study. Experimental neurology\| PubMed ID: 15473986	2004
Spinal implantation of hNT neurons and neuronal precursors: graft survival and functional effects in rats with ischemic spastic paraplegia. The European journal of neuroscience\| PubMed ID: 15525281	2004
Synaptogenesis and amino acid release from long term embryonic rat spinal cord neuronal culture using tissue culture inserts. Journal of neuroscience methods\| PubMed ID: 15585285	2005
The activation of spinal N-methyl-D-aspartate receptors may contribute to degeneration of spinal motor neurons induced by neuraxial morphine after a noninjurious interval of spinal cord isch... Anesthesia and analgesia\| PubMed ID: 15673851	2005
The evidence for nitric oxide synthase immunopositivity in the monosynaptic Ia-motoneuron pathway of the dog. Experimental neurology\| PubMed ID: 15979072	2005
Measurement of peripheral muscle resistance in rats with chronic ischemia-induced paraplegia or morphine-induced rigidity using a semi-automated computer-controlled muscle resistance meter. Journal of neurotrauma\| PubMed ID: 16305323	2005
Immunohistochemical, histochemical and radioassay analysis of nitric oxide synthase immunoreactivity in the lumbar and sacral dorsal root ganglia of the dog. Cellular and molecular neurobiology\| PubMed ID: 16633899	2006
Development of baclofen tolerance in a rat model of chronic spasticity and rigidity. Neuroscience letters\| PubMed ID: 16716507	2006
Nitrergic proprioceptive afferents originating from quadriceps femoris muscle are related to monosynaptic Ia-motoneuron stretch reflex circuit in the dog. Cellular and molecular neurobiology\| PubMed ID: 16724275	2006
The effect of a spinal cord hemisection on changes in nitric oxide synthase pools in the site of injury and in regions located far away from the injured site. Cellular and molecular neurobiology\| PubMed ID: 16786429	2006
Low-speed subcellular fractionation method for determining noxious stimulus-evoked spinal neurokinin-1 receptor internalization. Journal of neuroscience methods\| PubMed ID: 17083983	2007
The distribution of primary nitric oxide synthase- and parvalbumin- immunoreactive afferents in the dorsal funiculus of the lumbosacral spinal cord in a dog. Cellular and molecular neurobiology\| PubMed ID: 17387607	2007
Morphologic and volumetric studies of the meibomian glands in elderly human eyelids. Cornea\| PubMed ID: 17525661	2007
Cell therapy and stem cells in animal models of motor neuron disorders. The European journal of neuroscience\| PubMed ID: 17897390	2007
Intravenous infusion of dexmedetomidine can prevent the degeneration of spinal ventral neurons induced by intrathecal morphine after a noninjurious interval of spinal cord ischemia in rats. Anesthesia and analgesia\| PubMed ID: 17898393	2007
Spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17942713	2007
The effect of N-nitro-L-arginine and aminoguanidine treatment on changes in constitutive and inducible nitric oxide synthases in the spinal cord after sciatic nerve transection. International journal of molecular medicine\| PubMed ID: 18360686	2008
Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18719118	2008
The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19176818	2009
Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery. Growth factors (Chur, Switzerland)\| PubMed ID: 19294549	2009
Transcriptional signature and memory retention of human-induced pluripotent stem cells. PloS one\| PubMed ID: 19763270	2009
Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury. Nature medicine\| PubMed ID: 20190766	2010
The pleotrophic effects of insulin-like growth factor-I on human spinal cord neural progenitor cells. Stem cells and development\| PubMed ID: 20406098	2010
Analysis of dosing regimen and reproducibility of intraspinal grafting of human spinal stem cells in immunosuppressed minipigs. Cell transplantation\| PubMed ID: 20412634	2010
The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers. PloS one\| PubMed ID: 20730054	2010
Suppression of stretch reflex activity after spinal or systemic treatment with AMPA receptor antagonist NGX424 in rats with developed baclofen tolerance. British journal of pharmacology\| PubMed ID: 20977450	2010
Identification of NO/sGC signalling in the bulbospinal respiratory pathway after C2-C3 hemisection of the spinal cord in rats. Acta histochemica\| PubMed ID: 21145575	2011
Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PloS one\| PubMed ID: 21407814	2011
Optimization of immunosuppressive therapy for spinal grafting of human spinal stem cells in a rat model of ALS. Cell transplantation\| PubMed ID: 21669047	2011
Spinal cord transection modifies neuronal nitric oxide synthase expression in medullar reticular nuclei and in the spinal cord and increases parvalbumin immunopositivity in motoneurons below... Acta histochemica\| PubMed ID: 22000862	2012
Chronic spinal compression model in minipigs: a systematic behavioral, qualitative, and quantitative neuropathological study. Journal of neurotrauma\| PubMed ID: 22029501	2012
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature\| PubMed ID: 22278060	2012
Combinational spinal GAD65 gene delivery and systemic GABA-mimetic treatment for modulation of spasticity. PloS one\| PubMed ID: 22291989	2012
In vivo gene knockdown in rat dorsal root ganglia mediated by self-complementary adeno-associated virus serotype 5 following intrathecal delivery. PloS one\| PubMed ID: 22403675	2012
Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell metabolism\| PubMed ID: 22560226	2012
Development of AMPA receptor and GABA B receptor-sensitive spinal hyper-reflexia after spinal air embolism in rat: a systematic neurological, electrophysiological and qualitative histopathol... Experimental neurology\| PubMed ID: 22721766	2012
Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation. PloS one\| PubMed ID: 22916141	2012
Long-distance growth and connectivity of neural stem cells after severe spinal cord injury. Cell\| PubMed ID: 22980985	2012
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23382207	2013
Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation. Stem cell research & therapy\| PubMed ID: 23710605	2013
Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: effect on spinally grafted human neural precursor survival. Experimental neurology\| PubMed ID: 23748136	2013
Signaling proteins in spinal parenchyma and dorsal root ganglion in rat with spinal injury-induced spasticity. Journal of proteomics\| PubMed ID: 23835433	2013
Repeated Baclofen treatment ameliorates motor dysfunction, suppresses reflex activity and decreases the expression of signaling proteins in reticular nuclei and lumbar motoneurons after spin... Acta histochemica\| PubMed ID: 24074748	2014
Neural stem cell dissemination after grafting to CNS injury sites. Cell\| PubMed ID: 24485445	2014
Pig models of neurodegenerative disorders: Utilization in cell replacement-based preclinical safety and efficacy studies. The Journal of comparative neurology\| PubMed ID: 24610493	2014
A transgenic minipig model of Huntington's Disease. Journal of Huntington's disease\| PubMed ID: 25063429	2013
Neural stem cells in models of spinal cord injury. Experimental neurology\| PubMed ID: 25079369	2014
Baclofen or nNOS inhibitor affect molecular and behavioral alterations evoked by traumatic spinal cord injury in rat spinal cord. The spine journal : official journal of the North American Spine Society\| PubMed ID: 25151131	2015
Proteome-wide analysis of neural stem cell differentiation to facilitate transition to cell replacement therapies. Expert review of proteomics\| PubMed ID: 25363140	2015
Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1. Neuron\| PubMed ID: 25801706	2015
Large animal and primate models of spinal cord injury for the testing of novel therapies. Experimental neurology\| PubMed ID: 25902036	2015
Human mutant huntingtin disrupts vocal learning in transgenic songbirds. Nature neuroscience\| PubMed ID: 26436900	2015
The α5 subunit containing GABAA receptors contribute to chronic pain. Pain\| PubMed ID: 26545088	2016
Surface N-glycoproteome patterns reveal key proteins of neuronal differentiation. Journal of proteomics\| PubMed ID: 26581640	2016
Thoracic 9 Spinal Transection-Induced Model of Muscle Spasticity in the Rat: A Systematic Electrophysiological and Histopathological Characterization. PloS one\| PubMed ID: 26713446	2015
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs. Neuron\| PubMed ID: 27112497	2016
172 A Phase I, Open-Label, Single-Site, Safety Study of Human Spinal Cord-Derived Neural Stem Cell Transplantation for the Treatment of Chronic Spinal Cord Injury. Neurosurgery\| PubMed ID: 27399451	2016
Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs. Molecular therapy. Methods & clinical development\| PubMed ID: 27462649	2016
A Review of Stem Cell Therapy for Spinal Cord Injury: Large Animal Models and the Frontier in Humans. World neurosurgery\| PubMed ID: 27876663	2017
A robust vitronectin-derived peptide for the scalable long-term expansion and neuronal differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (hNPCs). Acta biomaterialia\| PubMed ID: 27989923	2017
Immunosurveillance and immunoediting in MMTV-PyMT-induced mammary oncogenesis. Oncoimmunology\| PubMed ID: 28344881	2017