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Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice
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Neuroscience
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JoVE Journal Neuroscience
Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice

Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice

English

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16,964 Views

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08:32 min

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July 13, 2017

DOI:

10.3791/55770-v

DOI:
10.3791/55770-v

•

08:32 min
July 13, 2017

•

19 Views
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1Neuroregeneration Laboratory, Department of Anesthesiology,University of California, San Diego, 2Institute of Animal Physiology and Genetics,Czech Academy of Sciences, 3Department of Neurosurgery,University of California, San Diego, 4Institute of Neurobiology,Slovak Academy of Sciences

Summary

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The goal of the present study was to develop and validate the potency and safety of spinal adeno-associated virus 9 (AAV9)-mediated gene delivery by using a novel subpial gene delivery technique in adult mice.

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Tadokoro, T., Miyanohara, A., Navarro, M., Kamizato, K., Juhas, S., Juhasova, J., Marsala, S., Platoshyn, O., Curtis, E., Gabel, B., Ciacci, J., Lukacova, N., Bimbova, K., Marsala, M. Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice. J. Vis. Exp. (125), e55770, doi:10.3791/55770 (2017).

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