Guosheng Fu

Department of Cardiology, Zhejiang University School of Medicine

Affiliated withZhejiang University School of Medicine Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province Zhejiang University Hangzhou

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 18	2017
Publication title Cited by 2	2023

Other Publications

Article	Year
Relation of thrombomodulin, TFPI and plasma antioxidants in healthy individuals and patients with coronary heart disease. Acta cardiologica\| PubMed ID: 18664025	2008
The expression of L-selectin at transcription and translation level in hemorrhagic shock rat. Zhonghua nei ke za zhi\| PubMed ID: 12189119	2002
Polymorphisms in the coagulation factor VII gene and the risk of myocardial infarction in patients undergoing coronary angiography. Chinese medical journal\| PubMed ID: 12935410	2003
D-box is required for the degradation of human Shugoshin and chromosome alignment. Biochemical and biophysical research communications\| PubMed ID: 17448445	2007
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis. Cell research\| PubMed ID: 17621308	2007
Phospho-regulation of HsCdc14A By Polo-like kinase 1 is essential for mitotic progression. The Journal of biological chemistry\| PubMed ID: 17623655	2007
Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduction pathway. Journal of cardiovascular pharmacology\| PubMed ID: 17878755	2007
SDF-1alpha/CXCR4 decreases endothelial progenitor cells apoptosis under serum deprivation by PI3K/Akt/eNOS pathway. Atherosclerosis\| PubMed ID: 18384792	2008
Reduced number and activity of circulating endothelial progenitor cells in patients with idiopathic pulmonary arterial hypertension. Respiratory medicine\| PubMed ID: 18394873	2008
Puerarin reduces endothelial progenitor cells senescence through augmentation of telomerase activity. Vascular pharmacology\| PubMed ID: 18692596	2008
Minocycline reduces intracerebral hemorrhage-induced brain injury. Neurological research\| PubMed ID: 19061541	2009
Nicotine-reduced endothelial progenitor cell senescence through augmentation of telomerase activity via the PI3K/Akt pathway. Cytotherapy\| PubMed ID: 19499400	2009
In situ endothelialization of intravascular stents coated with an anti-CD34 antibody functionalized heparin-collagen multilayer. Biomaterials\| PubMed ID: 20149438	2010
Epigallocatechin-3 gallate, a green tea catechin, attenuated the downregulation of the cardiac gap junction induced by high glucose in neonatal rat cardiomyocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 20798525	2010
Heparin/collagen multilayer as a thromboresistant and endothelial favorable coating for intravascular stent. Journal of biomedical materials research. Part A\| PubMed ID: 21105161	2011
Down-regulation of connexin43 gap junction by serum deprivation in human endothelial cells was improved by (-)-Epigallocatechin gallate via ERK MAP kinase pathway. Biochemical and biophysical research communications\| PubMed ID: 21110950	2011
Prevention and reversal of atrial fibrillation inducibility and autonomic remodeling by low-level vagosympathetic nerve stimulation. Journal of the American College of Cardiology\| PubMed ID: 21272747	2011
Thymosin Î²4 activates integrin-linked kinase and decreases endothelial progenitor cells apoptosis under serum deprivation. Journal of cellular physiology\| PubMed ID: 21935929	2011
Rosiglitazone attenuates endothelial progenitor cell apoptosis induced by TNF-Î± via ERK/MAPK and NF-ÎºB signal pathways. Journal of pharmacological sciences\| PubMed ID: 22129539	2011
Endothelial progenitor cells: current development of their paracrine factors in cardiovascular therapy. Journal of cardiovascular pharmacology\| PubMed ID: 22157259	2012
MicroRNAs as potential novel therapeutic targets and tools for regulating paracrine function of endothelial progenitor cells. Medical science monitor : international medical journal of experimental and clinical research\| PubMed ID: 22739741	2012
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology\| PubMed ID: 23045301	2012
Thymosin β4 reduces senescence of endothelial progenitor cells via the PI3K/Akt/eNOS signal transduction pathway. Molecular medicine reports\| PubMed ID: 23151623	2013
Stretch current-induced abnormal impulses in CaMKIIδ knockout mouse ventricular myocytes. Journal of cardiovascular electrophysiology\| PubMed ID: 23279377	2013
MicroRNA-21 mediates the rapamycin-induced suppression of endothelial proliferation and migration. FEBS letters\| PubMed ID: 23313253	2013
Advanced Glycation End Product (AGE)-AGE Receptor (RAGE) System Upregulated Connexin43 Expression in Rat Cardiomyocytes via PKC and Erk MAPK Pathways. International journal of molecular sciences\| PubMed ID: 23348924	2013
A paradoxical outcome after ablation in patients with paroxysmal atrial fibrillation: only overweight patients might benefit from an enhanced PVI strategy. International journal of cardiology\| PubMed ID: 23608391	2013
O-GlcNAcylation involvement in high glucose-induced cardiac hypertrophy via ERK1/2 and cyclin D2. Amino acids\| PubMed ID: 23665912	2013
Mitotic regulator Mis18β interacts with and specifies the centromeric assembly of molecular chaperone holliday junction recognition protein (HJURP). The Journal of biological chemistry\| PubMed ID: 24519934	2014
A prospective, multicenter, randomized trial of paclitaxel-coated balloon versus paclitaxel-eluting stent for the treatment of drug-eluting stent in-stent restenosis: results from the PEPCAD... JACC. Cardiovascular interventions\| PubMed ID: 24556098	2014
Aliskiren-attenuated myocardium apoptosis via regulation of autophagy and connexin-43 in aged spontaneously hypertensive rats. Journal of cellular and molecular medicine\| PubMed ID: 24702827	2014
Nine-month angiographic and two-year clinical follow-up of polymer-free sirolimus-eluting stent versus durable-polymer sirolimus-eluting stent for coronary artery disease: the Nano randomize... Chinese medical journal\| PubMed ID: 24890170	2014
Leptin confers protection against TNF-α-induced apoptosis in rat cardiomyocytes. Biochemical and biophysical research communications\| PubMed ID: 25450703	2014
Inhibition of the mevalonate pathway ameliorates anoxia-induced down-regulation of FKBP12.6 and intracellular calcium handling dysfunction in H9c2 cells. Journal of molecular and cellular cardiology\| PubMed ID: 25636197	2015
Stromal cell-derived factor-1α prevents endothelial progenitor cells senescence and enhances re-endothelialization of injured arteries via human telomerase reverse transcriptase. Cell biology international\| PubMed ID: 25820929	2015
Breviscapine attenuatted contrast medium-induced nephropathy via PKC/Akt/MAPK signalling in diabetic mice. American journal of translational research\| PubMed ID: 27158329	2016
Safety and efficacy of autologous thymosin β4 pre-treated endothelial progenitor cell transplantation in patients with acute ST segment elevation myocardial infarction: A pilot study. Cytotherapy\| PubMed ID: 27288307	2016
Efficacy and safety of fenofibrate as an add-on in patients with elevated triglyceride despite receiving statin treatment. International journal of cardiology\| PubMed ID: 27434354	2016
Characterization of the epicardial substrate for catheter ablation of Brugada syndrome. Heart rhythm\| PubMed ID: 27453126	2016
Activation of liver X receptor attenuates lysophosphatidylcholine-induced IL-8 expression in endothelial cells via the NF-κB pathway and SUMOylation. Journal of cellular and molecular medicine\| PubMed ID: 27489081	2016
The Impact of Rosuvastatin on the Density Score of Coronary Artery Calcification in Coronary Artery Disease Patients with Type 2 Diabetes Mellitus: Rationale and Design of RosCal Study. Clinical drug investigation\| PubMed ID: 27541380	2016
p66Shc couples mechanical signals to RhoA through FAK-dependent recruitment of p115-RhoGEF and GEF-H1. Molecular and cellular biology\| PubMed ID: 27573018	2016
The Rho kinase inhibitor, fasudil, ameliorates diabetes-induced cardiac dysfunction by improving calcium clearance and actin remodeling. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 27576917	2017
Erratum to: The Rho kinase inhibitor, fasudil, ameliorates diabetes-induced cardiac dysfunction by improving calcium clearance and actin remodeling. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 27654967	2017
Resveratrol prevents endothelial progenitor cells from senescence and reduces the oxidative reaction via PPAR‑γ/HO‑1 pathways. Molecular medicine reports\| PubMed ID: 27840978	2016
RasGRF Couples Nox4-Dependent Endoplasmic Reticulum Signaling to Ras. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 27856453	2017
Clinical and multimodality imaging results at 6 months of a bioresorbable sirolimus-eluting scaffold for patients with single de novo coronary artery lesions: the NeoVas first-in-man trial. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology\| PubMed ID: 27866137	2016
NADPH oxidase activation played a critical role in the oxidative stress process in stable coronary artery disease. American journal of translational research\| PubMed ID: 28077995	2016
Fn14 is regulated via the RhoA pathway and mediates nuclear factor-kappaB activation by Angiotensin II. American journal of translational research\| PubMed ID: 28078010	2016
PKC/NADPH oxidase are involved in the protective effect of pioglitazone in high homocysteine-induced paracrine dyfunction in endothelial progenitor cells. American journal of translational research\| PubMed ID: 28386331	2017
miR-1231 exacerbates arrhythmia by targeting calciumchannel gene CACNA2D2 in myocardial infarction. American journal of translational research\| PubMed ID: 28469787	2017
Inhibition of mevalonate pathway prevents ischemia-induced cardiac dysfunction in rats via RhoA-independent signaling pathway. Cardiovascular therapeutics\| PubMed ID: 28665545	2017
A Randomized Comparison of Biodegradable Polymer- and Permanent Polymer-coated Platinum Chromium Everolimus-ElutingCoronary Stents in China: The EVOLVE China Study. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology\| PubMed ID: 28741576	2017
Heart rate control is associated with reduced cardiovascular events in Asian patients with coronary artery disease treated with bisoprolol (BISO-CAD): results from a multi-national, real-wor... Current medical research and opinion\| PubMed ID: 28766382	2017
High glucose and free fatty acids induce endothelial progenitor cell senescence via PGC-1α/SIRT1 signaling pathway. Cell biology international\| PubMed ID: 28786152	2017
Efficacy and safety of renal denervation for Chinese patients with resistant hypertension using a microirrigated catheter: study design and protocol for a prospective multicentre randomised ... BMJ open\| PubMed ID: 28864691	2017
Photothermal-assisted surface-mediated gene delivery for enhancing transfection efficiency. Biomaterials science\| PubMed ID: 31588463	2019
Long non-coding RNA PCAT-1 promotes cardiac fibroblast proliferation via upregulating TGF-β1. European review for medical and pharmacological sciences\| PubMed ID: 31841207	2019
Bone marrow mesenchymal stem cell-secreted exosomes carrying microRNA-125b protect against myocardial ischemia reperfusion injury via targeting SIRT7. Molecular and cellular biochemistry\| PubMed ID: 31858380	2020
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells. BMC cardiovascular disorders\| PubMed ID: 31888640	2019
Rosuvastatin Reverses Hypertension-Induced Changes in the Aorta Structure and Endothelium-Dependent Relaxation in Rats Through Suppression of Apoptosis and Inflammation. Journal of cardiovascular pharmacology\| PubMed ID: 32205566	2020
Biodegradable phosphorylcholine copolymer for cardiovascular stent coating. Journal of materials chemistry. B\| PubMed ID: 32458930	2020
Variability in blood lipids affects the neutrophil to lymphocyte ratio in patients undergoing elective percutaneous coronary intervention: a retrospective study. Lipids in health and disease\| PubMed ID: 32493321	2020
TANK-binding kinase 1 alleviates myocardial ischemia/reperfusion injury through regulating apoptotic pathway. Biochemical and biophysical research communications\| PubMed ID: 32505355	2020
Detection of peripherally inserted central catheter (PICC) in chest X-ray images: A multi-task deep learning model. Computer methods and programs in biomedicine\| PubMed ID: 32738678	2020
Effect of Shexiang Tongxin dropping pill on stable coronary artery disease patients with normal fractional flow reserve and coronary microvascular disease: A study protocol. Medicine\| PubMed ID: 32957332	2020
The influence of substrate stiffness on osteogenesis of vascular smooth muscle cells. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 33096417	2021
The impact of homocysteine on the risk of coronary artery diseases in individuals with diabetes: a Mendelian randomization study. Acta diabetologica\| PubMed ID: 33113028	2021
Impact of increased inflammation biomarkers on periprocedural myocardial infarction in patients undergoing elective percutaneous coronary intervention: a cohort study. Journal of thoracic disease\| PubMed ID: 33209373	2020
Substrate stiffness differentially impacts autophagy of endothelial cells and smooth muscle cells. Bioactive materials\| PubMed ID: 33210033	2021
Weighted gene co-expression network analysis identified underlying hub genes and mechanisms in the occurrence and development of viral myocarditis. Annals of translational medicine\| PubMed ID: 33313093	2020
Comparison of low-density lipoprotein cholesterol/high-density lipoprotein cholesterol and total cholesterol/high-density lipoprotein cholesterol for the prediction of thin-cap fibroatheroma... Journal of geriatric cardiology : JGC\| PubMed ID: 33343645	2020
Methotrexate Therapy Promotes Cell Coverage and Stability in in-Stent Neointima. Cardiovascular drugs and therapy\| PubMed ID: 33394362	2021
Predictors of recurrent angina in patients with no need for secondary revascularization. World journal of emergency medicine\| PubMed ID: 33505549	2021
Expression of farnesyl pyrophosphate synthase is increased in diabetic cardiomyopathy. Cell biology international\| PubMed ID: 33595160	2021
Safety and Efficacy of Perioperative Use of Evolocumab in Myocardial Infarction Patients: Study Protocol for a Multicentre Randomized Controlled Trial. Advances in therapy\| PubMed ID: 33638801	2021
Effects of salvianolate on microcirculatory disturbance in patients with stable coronary heart disease: study protocol for a randomized controlled trial. Trials\| PubMed ID: 33685500	2021
Feasibility and safety of both His bundle pacing and left bundle branch area pacing in atrial fibrillation patients: intermediate term follow-up. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing\| PubMed ID: 33723691	2021
Comparison of rotational atherectomy and modified balloons prior to drug-eluting stent implantation for the treatment of heavily calcified coronary lesions. Medicine\| PubMed ID: 33761735	2021
Mitochondria-associated membrane-modulated Ca transfer: A potential treatment target in cardiac ischemia reperfusion injury and heart failure. Life sciences\| PubMed ID: 33864818	2021
Genetically predicted serum uric acid levels and the risk of coronary artery disease in patients with diabetes: A Mendelian randomization study. Nutrition, metabolism, and cardiovascular diseases : NMCD\| PubMed ID: 33975736	2021
β-blocker use before elective percutaneous coronary intervention as a risk factor for periprocedural myocardial injury incidence in male patients below 75 years old: a single-center retrospe... Annals of palliative medicine\| PubMed ID: 34044554	2021
miR-22 eluting cardiovascular stent based on a self-healable spongy coating inhibits in-stent restenosis. Bioactive materials\| PubMed ID: 34095625	2021
PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart. Circulation\| PubMed ID: 34102853	2021
Feasibility and Outcomes of Upgrading to Left Bundle Branch Pacing in Patients With Pacing-Induced Cardiomyopathy and Infranodal Atrioventricular Block. Frontiers in cardiovascular medicine\| PubMed ID: 34195236	2021
iPLAβ Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury. Cells\| PubMed ID: 34207793	2021
Identification of Underlying Hub Genes Associated with Hypertrophic Cardiomyopathy by Integrated Bioinformatics Analysis. Pharmacogenomics and personalized medicine\| PubMed ID: 34285551	2021
Long Noncoding RNA Promotes Angiotensin II-Induced Renal Fibrosis by Binding to Mineralocorticoid Receptor and Negatively Regulating MicroR-29b-3p. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 34333990	2021
Comparison of synchronization between left bundle branch and his bundle pacing in atrial fibrillation patients: An intra-patient-controlled study. Pacing and clinical electrophysiology : PACE\| PubMed ID: 34337768	2021
Intrastent haematoma after treatment with a drug-eluting balloon for in-stent restenosis: a case report. European heart journal. Case reports\| PubMed ID: 34377925	2021
Genetic Determinants of Increased Body Mass Index Partially Mediate the Effect of Elevated Birth Weight on the Increased Risk of Atrial Fibrillation. Frontiers in cardiovascular medicine\| PubMed ID: 34422928	2021
Downregulation of activating transcription factor 4 attenuates lysophosphatidycholine-induced inflammation via the NF-κB pathway. European journal of pharmacology\| PubMed ID: 34582847	2021
The impact of serum 25-hydroxyvitamin D, calcium, and parathyroid hormone levels on the risk of coronary artery disease in patients with diabetes: a Mendelian randomization study. Nutrition journal\| PubMed ID: 34602077	2021
Dabigatran Use after Argatroban for Heparin-induced Thrombocytopenia with Thrombosis: A Case Series and Literature Review. Annals of vascular surgery\| PubMed ID: 34656708	2022
Bioinspired NO release coating enhances endothelial cells and inhibits smooth muscle cells. Journal of materials chemistry. B\| PubMed ID: 34698745	2022
Sacubitril/Valsartan in the Treatment of Right Ventricular Dysfunction in Patients With Heart Failure With Reduced Ejection Fraction: A Real-world Study. Journal of cardiovascular pharmacology\| PubMed ID: 34711748	2022
Mean Scar Entropy by Late Gadolinium Enhancement Cardiac Magnetic Resonance Is Associated With Ventricular Arrhythmias Events in Hypertrophic Cardiomyopathy. Frontiers in cardiovascular medicine\| PubMed ID: 34869672	2021
Effects of Metoprolol on Periprocedural Myocardial Infarction After Percutaneous Coronary Intervention (Type 4a MI): An Inverse Probability of Treatment Weighting Analysis. Frontiers in cardiovascular medicine\| PubMed ID: 34888360	2021
Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell research\| PubMed ID: 34997220	2022
Anatomical and histological assessment of left bundle branch area pacing in human heart with refractory heart failure. ESC heart failure\| PubMed ID: 35038791	2022
Dendritic cell-mediated chronic low-grade inflammation is regulated by the RAGE-TLR4-PKCβ signaling pathway in diabetic atherosclerosis. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 35062863	2022
Cardiomyocyte IL-1R2 protects heart from ischemia/reperfusion injury by attenuating IL-17RA-mediated cardiomyocyte apoptosis. Cell death & disease\| PubMed ID: 35087030	2022
Assessment of Ultra-Early Administration of Sacubitril Valsartan to Improve Cardiac Remodeling in Patients With Acute Myocardial Infarction Following Primary PCI: Rational and Design of a Pr... Frontiers in physiology\| PubMed ID: 35222091	2022
Comparison of diagnostic accuracy of immediate angiography derived residual quantitative flow ratio after bioresorbable scaffold and drug eluting stent implantation. Reviews in cardiovascular medicine\| PubMed ID: 35229550	2022
Admission electrolyte and osmotic pressure levels are associated with the incidence of contrast-associated acute kidney injury. Scientific reports\| PubMed ID: 35304524	2022
Current Opinions on New-Onset Left Bundle Branch Block after Transcatheter Aortic Valve Replacement and the Search for Physiological Pacing. Reviews in cardiovascular medicine\| PubMed ID: 35345257	2022
An Online Pre-procedural Nomogram for the Prediction of Contrast-Associated Acute Kidney Injury in Patients Undergoing Coronary Angiography. Frontiers in medicine\| PubMed ID: 35360720	2022
Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle. Cell death & disease\| PubMed ID: 35368021	2022
Systemic Immune-Inflammation Index Predicts Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Cross-Sectional Study. Frontiers in medicine\| PubMed ID: 35372392	2022
Mir-22-incorporated polyelectrolyte coating prevents intima hyperplasia after balloon-induced vascular injury. Biomaterials science\| PubMed ID: 35642971	2022
Development and Validation of a Risk Score in Chinese Patients With Chronic Heart Failure. Frontiers in cardiovascular medicine\| PubMed ID: 35647038	2022
Association of Hemoglobin Glycation Index With Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Retrospective Study. Frontiers in physiology\| PubMed ID: 35669583	2022
Transcriptome analysis uncovers the autophagy-mediated regulatory patterns of the immune microenvironment in dilated cardiomyopathy. Journal of cellular and molecular medicine\| PubMed ID: 35752958	2022
Association between electronic cigarettes use and whole blood cell among adults in the USA-a cross-sectional study of National Health and Nutrition Examination Survey analysis. Environmental science and pollution research international\| PubMed ID: 35834083	2022
Gensini score values for predicting periprocedural myocardial infarction: An observational study analysis. Medicine\| PubMed ID: 35866829	2022
Nanomaterials-Mediated Therapeutics and Diagnosis Strategies for Myocardial Infarction. Frontiers in chemistry\| PubMed ID: 35873037	2022
Farnesyl diphosphate synthase regulated endothelial proliferation and autophagy during rat pulmonary arterial hypertension induced by monocrotaline. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 35962329	2022
Appraising the Causal Association between Systemic Iron Status and Heart Failure Risk: A Mendelian Randomisation Study. Nutrients\| PubMed ID: 36014764	2022
Targeted delivery of liver X receptor agonist to inhibit neointimal hyperplasia by differentially regulating cell behaviors. Biomaterials science\| PubMed ID: 36018302	2022
Efficacy and safety of hybutimibe in combination with atorvastatin for treatment of hypercholesteremia among patients with atherosclerotic cardiovascular disease risk equivalent: A multicent... Frontiers in cardiovascular medicine\| PubMed ID: 36072875	2022
Association Between Contrast Volume-to-Creatinine Clearance Ratio and the Risk of Perioperative Myocardial Infarction After Elective Percutaneous Coronary Intervention. International heart journal\| PubMed ID: 36104241	2022
The association between nutritional risk and contrast-induced acute kidney injury in patients undergoing coronary angiography: a cross-sectional study. Nutrition journal\| PubMed ID: 36114539	2022
Inhibition of neointimal hyperplasia in balloon-induced vascular injuries in a rat model by miR-22 loading Laponite hydrogels. Biomaterials advances\| PubMed ID: 36228507	2022
Combined effects of physical activity and sedentary behavior on all-cause mortality in heart failure patients: A cohort study of national health and nutrition examination survey analysis. Frontiers in cardiovascular medicine\| PubMed ID: 36312250	2022
Targeting Theranostics of Atherosclerosis by Dual-Responsive Nanoplatform via Photoacoustic Imaging and Three-In-One Integrated Lipid Management. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 36394179	2023
Cardiovascular imaging in conduction system pacing: What does the clinician need? Pacing and clinical electrophysiology : PACE\| PubMed ID: 36516139	2022