Stefan Lehr

Department of Clinical Biochemistry and Pathobiochemistry, Heinrich Heine University

Affiliated withHeinrich Heine University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2017

Other Publications

Article	Year
Primary skin fibroblasts as human model system for proteome analysis. Proteomics\| PubMed ID: 11921444	2002
Reliability of EMG time-frequency measures of fatigue during repetitive lifting. Medicine and science in sports and exercise\| PubMed ID: 12165687	2002
Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo. The Journal of biological chemistry\| PubMed ID: 14988395	2004
Identification of major ERK-related phosphorylation sites in Gab1. Biochemistry\| PubMed ID: 15379552	2004
Effect of sterol regulatory element binding protein-1a on the mitochondrial protein pattern in human liver cells detected by 2D-DIGE. Biochemistry\| PubMed ID: 15794649	2005
Glucuronic acid can extend O-linked core 1 glycans, but it contributes only weakly to the negative surface charge of Drosophila melanogaster Schneider-2 cells. FEBS letters\| PubMed ID: 18417079	2008
A critical comparison between two classical and a kit-based method for mitochondria isolation. Proteomics\| PubMed ID: 19415664	2009
Combinatorial hexapeptide ligand libraries (ProteoMiner): an innovative fractionation tool for differential quantitative clinical proteomics. Archives of physiology and biochemistry\| PubMed ID: 19604127	2009
Enhancing mass spectrometry based serum profiling by a combination of free flow electrophoresis and ClinProt. Archives of physiology and biochemistry\| PubMed ID: 19888797	2009
Proteomics in health and disease. Archives of physiology and biochemistry\| PubMed ID: 19891519	2009
Validation of self-made fluorescent cyanine dyes for 2D gel-based multi-fluorescence protein analysis. Archives of physiology and biochemistry\| PubMed ID: 19911952	2009
Mass spectrometry-based proteomics and its potential use in haematological research. Archives of physiology and biochemistry\| PubMed ID: 19916740	2009
ProteoMiner™ and SELDI-TOF-MS: a robust and highly reproducible combination for biomarker discovery from whole blood serum. Archives of physiology and biochemistry\| PubMed ID: 20662595	2010
Targeting phosphoprotein profiling by combination of hydroxyapatite-based phosphoprotein enrichment and SELDI-TOF MS. Archives of physiology and biochemistry\| PubMed ID: 20726833	2010
Biomarker discovery using SELDI-TOF protein chip technology. Archives of physiology and biochemistry\| PubMed ID: 20839924	2010
Integrative proteomics for the future US HUPO Fifth Annual Conference from genes to function 22-25 February 2009, San Diego, CA, USA. Proteomics. Clinical applications\| PubMed ID: 21136984	2009
Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes\| PubMed ID: 21593202	2011
The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway. Apoptosis : an international journal on programmed cell death\| PubMed ID: 21739277	2011
Identification and validation of novel adipokines released from primary human adipocytes. Molecular & cellular proteomics : MCP\| PubMed ID: 21947364	2012
Qualitative characteristics of HDL in young patients of an acute myocardial infarction. Atherosclerosis\| PubMed ID: 22056215	2012
Adipokines: a treasure trove for the discovery of biomarkers for metabolic disorders. Proteomics. Clinical applications\| PubMed ID: 22213627	2012
Multifluorescence 2D gel imaging and image analysis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22311751	2012
Combination of highly efficient hexapeptide ligand library-based sample preparation with 2D DIGE for the analysis of the hidden human serum/plasma proteome. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22311760	2012
Chemerin as biomarker for insulin sensitivity in males without typical characteristics of metabolic syndrome. Archives of physiology and biochemistry\| PubMed ID: 22335466	2012
Sex steroid-induced changes in circulating monocyte chemoattractant protein-1 levels may contribute to metabolic dysfunction in obese men. The Journal of clinical endocrinology and metabolism\| PubMed ID: 22523336	2012
Genetic variants in central metabolic genes influence some but not all relations of inflammatory markers in a collective with polycystic ovary syndrome. Archives of physiology and biochemistry\| PubMed ID: 22738153	2012
Multiplex immunoassays: an invaluable tool for biomarker discovery and validation. Archives of physiology and biochemistry\| PubMed ID: 22747464	2012
Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes. Molecular & cellular proteomics : MCP\| PubMed ID: 23382103	2013
2D-ToGo workflow: increasing feasibility and reproducibility of 2-dimensional gel electrophoresis. Archives of physiology and biochemistry\| PubMed ID: 23679042	2013
So close and yet so far: mitochondria and peroxisomes are one but with specific talents. Archives of physiology and biochemistry\| PubMed ID: 23705958	2013
The impact of pre-analytical conditions on the serum proteome: heat-stabilization versus nitrogen storage. Archives of physiology and biochemistry\| PubMed ID: 23826811	2013
2-dimensional gel electrophoresis reloaded. Archives of physiology and biochemistry\| PubMed ID: 23837539	2013
A mutation in the c-fos gene associated with congenital generalized lipodystrophy. Orphanet journal of rare diseases\| PubMed ID: 23919306	2013
Cytokine response of primary human myotubes in an in vitro exercise model. American journal of physiology. Cell physiology\| PubMed ID: 23926130	2013
Secretome profiling of primary human skeletal muscle cells. Biochimica et biophysica acta\| PubMed ID: 23994228	2014
The secretome of the working human skeletal muscle--a promising opportunity to combat the metabolic disaster? Proteomics. Clinical applications\| PubMed ID: 24376246	2014
Profiling of low molecular weight proteins in plasma from locally irradiated individuals. Journal of radiation research\| PubMed ID: 24570173	2014
Interleukin-6-dependent phenotypic modulation of cardiac fibroblasts after acute myocardial infarction. Basic research in cardiology\| PubMed ID: 25236954	2014
Identification of novel adipokines differential regulated in C57BL/Ks and C57BL/6. Archives of physiology and biochemistry\| PubMed ID: 25319219	2014
Proteomics in practice. Archives of physiology and biochemistry\| PubMed ID: 25353340	2014
Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2. Archives of physiology and biochemistry\| PubMed ID: 25353341	2014
Preparation of "functional" mitochondria: a challenging business. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25630998	2015
Isolation and quality control of functional mitochondria. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25630999	2015
Deficiency in lymphotoxin β receptor protects from atherosclerosis in apoE-deficient mice. Circulation research\| PubMed ID: 25740843	2015
Peroxisomes compensate hepatic lipid overflow in mice with fatty liver. Biochimica et biophysica acta\| PubMed ID: 25790917	2015
Investigating the adipose tissue secretome: a protocol to generate high-quality samples appropriate for comprehensive proteomic profiling. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25820712	2015
Methods for proteomics-based analysis of the human muscle secretome using an in vitro exercise model. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25820713	2015
Deep serum discoveries: SDF-1α and HSA fragments in myelodysplastic syndromes. American journal of hematology\| PubMed ID: 26010554	2015
Increased cathepsin D protein expression is a biomarker for osteosarcomas, pulmonary metastases and other bone malignancies. Oncotarget\| PubMed ID: 26203049	2015
Deletion of Hyaluronan Synthase 3 Inhibits Neointimal Hyperplasia in Mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26586662	2016
Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes. The Journal of clinical endocrinology and metabolism\| PubMed ID: 26829444	2016
Untargeted mass spectrometric approach in metabolic healthy offspring of patients with type 2 diabetes reveals medium-chain acylcarnitine as potential biomarker for lipid induced glucose int... Archives of physiology and biochemistry\| PubMed ID: 27373781	2016
Impact of fibroblast growth factor 21 on the secretome of human perivascular preadipocytes and adipocytes: a targeted proteomics approach. Archives of physiology and biochemistry\| PubMed ID: 27494767	2016
Oxygen and differentiation status modulate the effect of X-ray irradiation on physiology and mitochondrial proteome of human neuroblastoma cells. Archives of physiology and biochemistry\| PubMed ID: 27615280	2016
Mass spectrometry in life science research. Archives of physiology and biochemistry\| PubMed ID: 27808565	2016
Lipidomics-Reshaping the Analysis and Perception of Type 2 Diabetes. International journal of molecular sciences\| PubMed ID: 27827927	2016
Association between copy-number variation on metabolic phenotypes and HDL-C levels in patients with polycystic ovary syndrome. Molecular biology reports\| PubMed ID: 27878529	2017
Differential Patterns of Impaired Cardiorespiratory Fitness and Cardiac Autonomic Dysfunction in Recently Diagnosed Type 1 and Type 2 Diabetes. Diabetes care\| PubMed ID: 27899499	2017
Mechanisms of Insulin Resistance in Primary and Secondary Non-Alcoholic Fatty Liver. Diabetes\| PubMed ID: 28490610	2017