Nikolai Klymiuk

Institute of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilian University

Affiliated withLudwig-Maximilian University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2017

Other Publications

Article	Year
Characterization of porcine endogenous retrovirus gamma pro-pol nucleotide sequences. Journal of virology\| PubMed ID: 12388734	2002
Recombination analysis of human-tropic porcine endogenous retroviruses. The Journal of general virology\| PubMed ID: 13679607	2003
Characterization of endogenous retroviruses in sheep. Journal of virology\| PubMed ID: 14512574	2003
Reliable classification and recombination analysis of porcine endogenous retroviruses. Virus genes\| PubMed ID: 15830154	2005
Phylogeny, recombination and expression of porcine endogenous retrovirus gamma2 nucleotide sequences. The Journal of general virology\| PubMed ID: 16528048	2006
Concise classification of the genomic porcine endogenous retroviral gamma1 load to defined lineages. Virology\| PubMed ID: 17964627	2008
Genomic, tissue expression, and protein characterization of pCLCA1, a putative modulator of cystic fibrosis in the pig. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 19755716	2009
Genetic modification of pigs as organ donors for xenotransplantation. Molecular reproduction and development\| PubMed ID: 19998476	2010
Transgenic pigs for xenotransplantation: selection of promoter sequences for reliable transgene expression. Current opinion in organ transplantation\| PubMed ID: 20061949	2010
Transgenic pigs as models for translational biomedical research. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 20339830	2010
Tissue and cellular expression patterns of porcine CFTR: similarities to and differences from human CFTR. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 20498480	2010
First inducible transgene expression in porcine large animal models. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22138035	2012
The porcine chloride channel calcium-activated family member pCLCA4a mirrors lung expression of the human hCLCA4. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 22205680	2012
Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice. Diabetes\| PubMed ID: 22522620	2012
Potential of primary kidney cells for somatic cell nuclear transfer mediated transgenesis in pig. BMC biotechnology\| PubMed ID: 23140586	2012
Permanent neonatal diabetes in INS(C94Y) transgenic pigs. Diabetes\| PubMed ID: 23274907	2013
Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set. BMC biotechnology\| PubMed ID: 23688045	2013
Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle. Human molecular genetics\| PubMed ID: 23784375	2013
Activation of the lectin pathway of complement in pig-to-human xenotransplantation models. Transplantation\| PubMed ID: 23958924	2013
Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs. Transplantation\| PubMed ID: 24150517	2014
Homologous recombination contributes to the repair of zinc-finger-nuclease induced double strand breaks in pig primary cells and facilitates recombination with exogenous DNA. Journal of biotechnology\| PubMed ID: 24613297	2014
Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood. Xenotransplantation\| PubMed ID: 24635052	2014
Pig-to-baboon heterotopic heart transplantation--exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimen... Xenotransplantation\| PubMed ID: 25847282	2015
Virus safety of islet cell transplantation from transgenic pigs to marmosets. Virus research\| PubMed ID: 25956348	2015
Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions. Transplantation\| PubMed ID: 25965410	2015
Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype. PloS one\| PubMed ID: 26474299	2015
Engraftment and reversal of diabetes after intramuscular transplantation of neonatal porcine islet-like clusters. Xenotransplantation\| PubMed ID: 26490671	2015
Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies. Toxicologic pathology\| PubMed ID: 26511847	2016
Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets. PloS one\| PubMed ID: 26600426	2015
Pre-clinical heterotopic intrathoracic heart xenotransplantation: a possibly useful clinical technique. Xenotransplantation\| PubMed ID: 26602740	2015
Inhibition of complement component C5 prevents clotting in an ex vivo model of xenogeneic activation of coagulation. Xenotransplantation\| PubMed ID: 26773447	2016
Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft. Nature communications\| PubMed ID: 27045379	2016
Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation. Transplantation\| PubMed ID: 27077599	2016
Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs. PloS one\| PubMed ID: 27175998	2016
Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy. Scientific reports\| PubMed ID: 27634466	2016
Direct introduction of gene constructs into the pronucleus-like structure of cloned embryos: a new strategy for the generation of genetically modified pigs. Transgenic research\| PubMed ID: 27943082	2017
Transgenic expression of human leukocyte antigen-E attenuates GalKO.hCD46 porcine lung xenograft injury. Xenotransplantation\| PubMed ID: 28258595	2017
Vessel network architecture of adult human islets promotes distinct cell-cell interactions in situ and is altered after transplantation. Endocrinology\| PubMed ID: 28324008	2017
Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood. Scientific reports\| PubMed ID: 28667310	2017