Eckhard Wolf

Institute of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilian University

Affiliated withLudwig-Maximilian University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2017

Other Publications

Article	Year
Changes of higher order chromatin arrangements during major genome activation in bovine preimplantation embryos. Experimental cell research\| PubMed ID: 19254712	2009
Systemic first-line phenotyping. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19266331	2009
Maternal inexperience as a risk factor of innate fear and PTSD-like symptoms in mice. Journal of psychiatric research\| PubMed ID: 19304295	2009
The endometrium responds differently to cloned versus fertilized embryos. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19307558	2009
Scrapie-infected transgenic mice expressing a laminin receptor decoy mutant reveal a prolonged incubation time associated with low levels of PrPres. Journal of molecular biology\| PubMed ID: 19324055	2009
The C-terminal cytoplasmic domain of human proEGF is a negative modulator of body and organ weights in transgenic mice. FEBS letters\| PubMed ID: 19328792	2009
Distribution and expression of porcine endogenous retroviruses in multi-transgenic pigs generated for xenotransplantation. Xenotransplantation\| PubMed ID: 19392721	2009
A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease? Investigative ophthalmology & visual science\| PubMed ID: 19407009	2009
A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell\| PubMed ID: 19490899	2009
Chronic growth hormone excess is associated with increased aldosterone: a study in patients with acromegaly and in growth hormone transgenic mice. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 19491373	2009
Evidence for estrogen-dependent uterine serpin (SERPINA14) expression during estrus in the bovine endometrial glandular epithelium and lumen. Biology of reproduction\| PubMed ID: 19494250	2009
N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels. Journal of biomedical science\| PubMed ID: 19505327	2009
Reprogramming of active and repressive histone modifications following nuclear transfer with rabbit mesenchymal stem cells and adult fibroblasts. Cloning and stem cells\| PubMed ID: 19508112	2009
Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. PloS one\| PubMed ID: 19562077	2009
Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection. Infection and immunity\| PubMed ID: 19596769	2009
Specific transgene expression in mouse pancreatic beta-cells under the control of the porcine insulin promoter. Molecular and cellular endocrinology\| PubMed ID: 19682540	2010
Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism. American journal of physiology. Renal physiology\| PubMed ID: 19692485	2009
Epigen transgenic mice develop enlarged sebaceous glands. The Journal of investigative dermatology\| PubMed ID: 19693025	2010
Germ-line transmission of lentiviral PGK-EGFP integrants in transgenic cattle: new perspectives for experimental embryology. Transgenic research\| PubMed ID: 19862638	2010
EGFR ligands exert diverging effects on male reproductive organs. Experimental and molecular pathology\| PubMed ID: 19931240	2010
Genetic modification of pigs as organ donors for xenotransplantation. Molecular reproduction and development\| PubMed ID: 19998476	2010
Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 20033184	2010
Betacellulin protects from pancreatitis by activating stress-activated protein kinase. Gastroenterology\| PubMed ID: 20038432	2010
Transgenic pigs for xenotransplantation: selection of promoter sequences for reliable transgene expression. Current opinion in organ transplantation\| PubMed ID: 20061949	2010
Escherichia coli infection induces distinct local and systemic transcriptome responses in the mammary gland. BMC genomics\| PubMed ID: 20184744	2010
Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function. Diabetes\| PubMed ID: 20185813	2010
Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice. PloS one\| PubMed ID: 20209148	2010
Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia. American journal of physiology. Renal physiology\| PubMed ID: 20219826	2010
Transgenic pigs as models for translational biomedical research. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 20339830	2010
Differential endometrial gene expression in pregnant and nonpregnant sows. Biology of reproduction\| PubMed ID: 20393170	2010
Genomic integration of adenoviral gene transfer vectors following transduction of fertilized mouse oocytes. Transgenic research\| PubMed ID: 20464633	2011
Quantification of leukocyte genomic 5-methylcytosine levels reveals epigenetic plasticity in healthy adult cloned cattle. Cellular reprogramming\| PubMed ID: 20677931	2010
Mouse phenotyping. Methods (San Diego, Calif.)\| PubMed ID: 20708688	2011
FISH on 3D preserved bovine and murine preimplantation embryos. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20809333	2010
Actions and interactions of progesterone and estrogen on transcriptome profiles of the bovine endometrium. Physiological genomics\| PubMed ID: 20876846	2010
Bovine endometrial metallopeptidases MMP14 and MMP2 and the metallopeptidase inhibitor TIMP2 participate in maternal preparation of pregnancy. Molecular and cellular endocrinology\| PubMed ID: 20887771	2011
Utilization of a mutagenesis screen to generate mouse models of hyperaldosteronism. Endocrinology\| PubMed ID: 21068155	2011
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation. PloS one\| PubMed ID: 21179475	2010
Formation of nucleoli in interspecies nuclear transfer embryos derived from bovine, porcine, and rabbit oocytes and nuclear donor cells of various species. Reproduction (Cambridge, England)\| PubMed ID: 21239525	2011
A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. Arthritis and rheumatism\| PubMed ID: 21305534	2011
Decreased incidence of papillomas in mice with impaired EGFR function during multi-stage skin carcinogenesis. Experimental dermatology\| PubMed ID: 21323750	2011
Increase of essential amino acids in the bovine uterine lumen during preimplantation development. Reproduction (Cambridge, England)\| PubMed ID: 21383026	2011
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia. Journal of cell science\| PubMed ID: 21406566	2011
Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice. The Journal of biological chemistry\| PubMed ID: 21467037	2011
Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 21553221	2011
Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells. Nature communications\| PubMed ID: 21772266	2011
Reduced amino acids in the bovine uterine lumen of cloned versus in vitro fertilized pregnancies prior to implantation. Cellular reprogramming\| PubMed ID: 21774685	2011
Cell arrest and cell death in mammalian preimplantation development: lessons from the bovine model. PloS one\| PubMed ID: 21811561	2011
Postnatal development of numbers and mean sizes of pancreatic islets and beta-cells in healthy mice and GIPR(dn) transgenic diabetic mice. PloS one\| PubMed ID: 21818396	2011
In vivo evidence for epidermal growth factor receptor (EGFR)-mediated release of prolactin from the pituitary gland. The Journal of biological chemistry\| PubMed ID: 21914800	2011
A transgenic mouse line expressing cre recombinase in pancreatic β-cells. Genesis (New York, N.Y. : 2000)\| PubMed ID: 21998080	2012
Lack of Pur-alpha alters postnatal brain development and causes megalencephaly. Human molecular genetics\| PubMed ID: 22010047	2012
Gene expression profiling of bovine peripartal placentomes: detection of molecular pathways potentially involved in the release of foetal membranes. Reproduction (Cambridge, England)\| PubMed ID: 22031715	2012
Comparison of the effects of early pregnancy with human interferon, alpha 2 (IFNA2), on gene expression in bovine endometrium. Biology of reproduction\| PubMed ID: 22034527	2012
Normal epidermal growth factor receptor signaling is dispensable for bone anabolic effects of parathyroid hormone. Bone\| PubMed ID: 22056328	2012
First inducible transgene expression in porcine large animal models. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22138035	2012
Clinical chemistry of human FcRn transgenic mice. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 22193411	2012
Negative feedback mechanisms surpass the effect of intrinsic EGFR activation during skin chemical carcinogenesis. The American journal of pathology\| PubMed ID: 22306420	2012
Human TNF-related apoptosis-inducing ligand-expressing dendritic cells from transgenic pigs attenuate human xenogeneic T cell responses. Xenotransplantation\| PubMed ID: 22360752	2012
Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans. PLoS genetics\| PubMed ID: 22438821	2012
Changing metabolic signatures of amino acids and lipids during the prediabetic period in a pig model with impaired incretin function and reduced β-cell mass. Diabetes\| PubMed ID: 22492530	2012
Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice. Diabetes\| PubMed ID: 22522620	2012
New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 22527485	2012
A new mouse model for studying EGFR-dependent gastric polyps. Biochimica et biophysica acta\| PubMed ID: 22579588	2012
Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo. PLoS pathogens\| PubMed ID: 22685399	2012
Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system. PloS one\| PubMed ID: 22701626	2012
Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22730437	2012
Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines. European journal of oral sciences\| PubMed ID: 22813216	2012
Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγ(null) mice engrafted with human peripheral blood mononuclear cells. Disease models & mechanisms\| PubMed ID: 22822046	2013
A porcine model of familial adenomatous polyposis. Gastroenterology\| PubMed ID: 22864254	2012
Transcriptome analyses of bovine, porcine and equine endometrium during the pre-implantation phase. Animal reproduction science\| PubMed ID: 22917876	2012
Innovations in phenotyping of mouse models in the German Mouse Clinic. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 22926221	2012
In-vivo biodegradation of extruded lipid implants in rabbits. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22964393	2012
The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22982378	2012
Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs. PloS one\| PubMed ID: 23071491	2012
Truncation of MIMT1 gene in the PEG3 domain leads to major changes in placental gene expression and stillbirth in cattle. Biology of reproduction\| PubMed ID: 23100617	2012
Potential of primary kidney cells for somatic cell nuclear transfer mediated transgenesis in pig. BMC biotechnology\| PubMed ID: 23140586	2012
Genetic deletion of the EGFR ligand epigen does not affect mouse embryonic development and tissue homeostasis. Experimental cell research\| PubMed ID: 23142483	2013
Completion of the swine genome will simplify the production of swine as a large animal biomedical model. BMC medical genomics\| PubMed ID: 23151353	2012
The endocytic adaptor Eps15 controls marginal zone B cell numbers. PloS one\| PubMed ID: 23226392	2012
Hosting the preimplantation embryo: potentials and limitations of different approaches for analysing embryo-endometrium interactions in cattle. Reproduction, fertility, and development\| PubMed ID: 23244829	2012
Permanent neonatal diabetes in INS(C94Y) transgenic pigs. Diabetes\| PubMed ID: 23274907	2013
NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways. Journal of translational medicine\| PubMed ID: 23294516	2013
Immune aspects of embryo-maternal cross-talk in the bovine uterus. Journal of reproductive immunology\| PubMed ID: 23432868	2013
SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities. DNA repair\| PubMed ID: 23518413	2013
Modeling hepatic osteodystrophy in Abcb4 deficient mice. Bone\| PubMed ID: 23545228	2013
Tissue-specific and minor inter-individual variation in imprinting of IGF2R is a common feature of Bos taurus Concepti and not correlated with fetal weight. PloS one\| PubMed ID: 23593146	2013
Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. PloS one\| PubMed ID: 23593477	2013
iTRAQ proteome analysis reflects a progressed differentiation state of epiblast derived versus inner cell mass derived murine embryonic stem cells. Journal of proteomics\| PubMed ID: 23603003	2013
Cytoplasmic mislocalization of POU3F4 due to novel mutations leads to deafness in humans and mice. Human mutation\| PubMed ID: 23606368	2013
High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner. The Journal of biological chemistry\| PubMed ID: 23620591	2013
Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set. BMC biotechnology\| PubMed ID: 23688045	2013
Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice. Human molecular genetics\| PubMed ID: 23748428	2013
Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle. Human molecular genetics\| PubMed ID: 23784375	2013
An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease. The American journal of pathology\| PubMed ID: 23791841	2013
Rapamycin extends murine lifespan but has limited effects on aging. The Journal of clinical investigation\| PubMed ID: 23863708	2013
Increased activation of the epidermal growth factor receptor in transgenic mice overexpressing epigen causes peripheral neuropathy. Biochimica et biophysica acta\| PubMed ID: 23899604	2013
Activation of the lectin pathway of complement in pig-to-human xenotransplantation models. Transplantation\| PubMed ID: 23958924	2013
Expression pattern of STAT5A gene during early bovine embryogenesis. Zygote (Cambridge, England)\| PubMed ID: 23981721	2015
Genetically engineered pig models for diabetes research. Transgenic research\| PubMed ID: 24065178	2014
Ligand-independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice. Experimental dermatology\| PubMed ID: 24079739	2013
Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs. Transplantation\| PubMed ID: 24150517	2014
Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice. PloS one\| PubMed ID: 24205203	2013
A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice. PloS one\| PubMed ID: 24278347	2013
Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24297939	2013
Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis. Molecular metabolism\| PubMed ID: 24327959	2013
Comparative and retrospective molecular analysis of Parapoxvirus (PPV) isolates. Virus research\| PubMed ID: 24373950	2014
The ABC of BTC: structural properties and biological roles of betacellulin. Seminars in cell & developmental biology\| PubMed ID: 24440602	2014
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43. The Journal of biological chemistry\| PubMed ID: 24515116	2014
No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease. The Journal of biological chemistry\| PubMed ID: 24567330	2014
Fine mapping of genome activation in bovine embryos by RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24591639	2014
Homologous recombination contributes to the repair of zinc-finger-nuclease induced double strand breaks in pig primary cells and facilitates recombination with exogenous DNA. Journal of biotechnology\| PubMed ID: 24613297	2014
Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood. Xenotransplantation\| PubMed ID: 24635052	2014
Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments. PloS one\| PubMed ID: 24896637	2014
Genome activation in bovine embryos: review of the literature and new insights from RNA sequencing experiments. Animal reproduction science\| PubMed ID: 24975847	2014
Uniformity of nucleosome preservation pattern in Mammalian sperm and its connection to repetitive DNA elements. Developmental cell\| PubMed ID: 24998597	2014
Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus. PloS one\| PubMed ID: 25025770	2014
DRO1 inactivation drives colorectal carcinogenesis in ApcMin/+ mice. Molecular cancer research : MCR\| PubMed ID: 25053805	2014
Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice. Diabetes\| PubMed ID: 25071027	2015
Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice. Journal of biomedical science\| PubMed ID: 25084970	2014
Stage-specific proteome signatures in early bovine embryo development. Journal of proteome research\| PubMed ID: 25102770	2014
Pleiotropic functions for transcription factor zscan10. PloS one\| PubMed ID: 25111779	2014
Proteome analysis of early lineage specification in bovine embryos. Proteomics\| PubMed ID: 25143135	2015
Nuclear transfer and transgenesis in the pig. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25287337	2015
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts. Nature communications\| PubMed ID: 25333900	2014
Uterine responses to the preattachment embryo in domestic ungulates: recognition of pregnancy and preparation for implantation. Annual review of animal biosciences\| PubMed ID: 25387113	2015
Uromodulin retention in thick ascending limb of Henle's loop affects SCD1 in neighboring proximal tubule: renal transcriptome studies in mouse models of uromodulin-associated kidney disease. PloS one\| PubMed ID: 25409434	2014
Reprogramming of fibroblast nuclei in cloned bovine embryos involves major structural remodeling with both striking similarities and differences to nuclear phenotypes of in vitro fertilized ... Nucleus (Austin, Tex.)\| PubMed ID: 25482066	2014
Positional changes of a pluripotency marker gene during structural reorganization of fibroblast nuclei in cloned early bovine embryos. Nucleus (Austin, Tex.)\| PubMed ID: 25495180	2014
Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine\| PubMed ID: 25636453	2015
Efavirenz Causes Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Endothelial Cells. Cardiovascular toxicology\| PubMed ID: 25666561	2016
Commentary on "Meta-analysis of the independent and cumulative effects of multiple genetic modifications on pig lung xenograft performance during ex vivo perfusion with human blood" (by Harr... Xenotransplantation\| PubMed ID: 25711248	2015
Viable pigs with a conditionally-activated oncogenic KRAS mutation. Transgenic research\| PubMed ID: 25716163	2015
Glucose tolerance tests for systematic screening of glucose homeostasis in mice. Current protocols in mouse biology\| PubMed ID: 25727201	2015
Pig-to-baboon heterotopic heart transplantation--exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimen... Xenotransplantation\| PubMed ID: 25847282	2015
Inactivation of Itf2 promotes intestinal tumorigenesis in Apc(Min/+) mice. Biochemical and biophysical research communications\| PubMed ID: 25869068	2015
Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition. Journal of translational medicine\| PubMed ID: 25890210	2015
Remodeling of the Nuclear Envelope and Lamina during Bovine Preimplantation Development and Its Functional Implications. PloS one\| PubMed ID: 25932910	2015
Virus safety of islet cell transplantation from transgenic pigs to marmosets. Virus research\| PubMed ID: 25956348	2015
Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions. Transplantation\| PubMed ID: 25965410	2015
Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy. Acta neuropathologica\| PubMed ID: 26025657	2015
Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum. Current protocols in mouse biology\| PubMed ID: 26069059	2013
Blood Collection from Mice and Hematological Analyses on Mouse Blood. Current protocols in mouse biology\| PubMed ID: 26069060	2013
Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers. Genome research\| PubMed ID: 26156321	2015
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics. Nature genetics\| PubMed ID: 26214591	2015
Xenotransplantation of Cells, Tissues, Organs and the German Research Foundation Transregio Collaborative Research Centre 127. Advances in experimental medicine and biology\| PubMed ID: 26306448	2015
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription. Nature communications\| PubMed ID: 26383020	2015
Phytohemagglutinin facilitates the aggregation of blastomere pairs from Day 5 donor embryos with Day 4 host embryos for chimeric bovine embryo multiplication. Theriogenology\| PubMed ID: 26409823	2015
Metamizol Relieves Pain Without Interfering With Cerulein-Induced Acute Pancreatitis in Mice. Pancreas\| PubMed ID: 26418910	2016
Incretin actions and consequences of incretin-based therapies: lessons from complementary animal models. The Journal of pathology\| PubMed ID: 26455904	2016
Pigs pave a way to de novo formation of functional human kidneys. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26460047	2015
Engraftment and reversal of diabetes after intramuscular transplantation of neonatal porcine islet-like clusters. Xenotransplantation\| PubMed ID: 26490671	2015
Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD-deficient IGFBP-2 variant in female transgenic mice. Aging cell\| PubMed ID: 26507795	2016
Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies. Toxicologic pathology\| PubMed ID: 26511847	2016
MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26564819	2016
Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets. PloS one\| PubMed ID: 26600426	2015
Pre-clinical heterotopic intrathoracic heart xenotransplantation: a possibly useful clinical technique. Xenotransplantation\| PubMed ID: 26602740	2015
3D structured illumination microscopy of mammalian embryos and spermatozoa. BMC developmental biology\| PubMed ID: 26610350	2015
Stage-dependent remodeling of the nuclear envelope and lamina during rabbit early embryonic development. The Journal of reproduction and development\| PubMed ID: 26640117	2016
Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation. Thrombosis and haemostasis\| PubMed ID: 26676803	2016
Pillars Article: CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs. Cell. 1999. 99: 23-33. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26685313	2016
Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice. American journal of physiology. Renal physiology\| PubMed ID: 26764204	2016
Inhibition of complement component C5 prevents clotting in an ex vivo model of xenogeneic activation of coagulation. Xenotransplantation\| PubMed ID: 26773447	2016
Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 26803617	2016
Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice. Journal of inherited metabolic disease\| PubMed ID: 26830550	2016
Tissue Sampling Guides for Porcine Biomedical Models. Toxicologic pathology\| PubMed ID: 26883152	2016
First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 2b: ... Xenotransplantation\| PubMed ID: 26926888	2016
Growth hormone (GH)-transgenic insulin-like growth factor 1 (IGF1)-deficient mice allow dissociation of excess GH and IGF1 effects on glomerular and tubular growth. Physiological reports\| PubMed ID: 26997624	2016
Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice. PloS one\| PubMed ID: 27003440	2016
Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft. Nature communications\| PubMed ID: 27045379	2016
Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation. Transplantation\| PubMed ID: 27077599	2016
Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs. PloS one\| PubMed ID: 27175998	2016
Comparative aspects of rodent and nonrodent animal models for mechanistic and translational diabetes research. Theriogenology\| PubMed ID: 27180329	2016
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice. Diabetes\| PubMed ID: 27284107	2016
Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing. Scientific reports\| PubMed ID: 27353424	2016
Missense Mutation of POU Domain Class 3 Transcription Factor 3 in Pou3f3L423P Mice Causes Reduced Nephron Number and Impaired Development of the Thick Ascending Limb of the Loop of Henle. PloS one\| PubMed ID: 27420727	2016
Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus). Journal of the American Association for Laboratory Animal Science : JAALAS\| PubMed ID: 27423143	2016
Progress in Clinical Encapsulated Islet Xenotransplantation. Transplantation\| PubMed ID: 27482959	2016
A mouse model for ulcerative colitis based on NOD-scid IL2R γnull mice reconstituted with peripheral blood mononuclear cells from affected individuals. Disease models & mechanisms\| PubMed ID: 27491073	2016
Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy. Scientific reports\| PubMed ID: 27634466	2016
Loss of DRO1/CCDC80 results in obesity and promotes adipocyte differentiation. Molecular and cellular endocrinology\| PubMed ID: 27645901	2017
Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 27671791	2016
The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations. G3 (Bethesda, Md.)\| PubMed ID: 27815347	2016
Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms. Molecular neurobiology\| PubMed ID: 27914009	2016
Direct introduction of gene constructs into the pronucleus-like structure of cloned embryos: a new strategy for the generation of genetically modified pigs. Transgenic research\| PubMed ID: 27943082	2017
Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium. Journal of the American College of Cardiology\| PubMed ID: 28081822	2017
Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD). Scientific reports\| PubMed ID: 28220896	2017
Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice. Biochimica et biophysica acta\| PubMed ID: 28235645	2017
Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice. Molecular metabolism\| PubMed ID: 28271032	2017
INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters. Diabetologia\| PubMed ID: 28315950	2017
Vessel network architecture of adult human islets promotes distinct cell-cell interactions in situ and is altered after transplantation. Endocrinology\| PubMed ID: 28324008	2017
Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes. Nature genetics\| PubMed ID: 28369036	2017
Retinopathy with central oedema in an INS (C94Y) transgenic pig model of long-term diabetes. Diabetologia\| PubMed ID: 28480495	2017
Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016. Molecular and cellular pediatrics\| PubMed ID: 28516419	2017
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression. Scientific reports\| PubMed ID: 28546545	2017
Meis1: effects on motor phenotypes and the sensorimotor system in mice. Disease models & mechanisms\| PubMed ID: 28645892	2017
Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood. Scientific reports\| PubMed ID: 28667310	2017
The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes. Molecular metabolism\| PubMed ID: 28752056	2017
Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice. Nature communications\| PubMed ID: 28761067	2017
Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 (I27N) mutant mice. Journal of biomedical science\| PubMed ID: 28818080	2017