Toni Ibrahim

Osteoncology and Rare Tumors Center, IRCCS

Affiliated withIRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy

Research Area

Cancer Research

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 6	2017
Publication title Cited by 16	2018
Publication title Cited by 9	2018

Other Publications

Article	Year
"Misura" project: a retrospective survey on the use of 5fluorouracil in the treatment of colorectal cancer in 24 Italian clinical centers. Tumori\| PubMed ID: 12088248	2002
Docetaxel followed by gemcitabine in the treatment of advanced non-small cell lung cancer: a phase I study. Tumori\| PubMed ID: 12088266	2002
Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients. Therapeutic drug monitoring\| PubMed ID: 12352929	2002
Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer. Clinical pharmacology and therapeutics\| PubMed ID: 12496744	2002
Innovative sequence of docetaxel-gemcitabine based on preclinical data in the treatment of advanced non small cell lung cancer: a phase I study. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 15639725	2005
Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinet... Therapeutic drug monitoring\| PubMed ID: 15905808	2005
Osteonecrosis of the jaw in patients with bone metastases treated with bisphosphonates: a retrospective study. The oncologist\| PubMed ID: 18378544	2008
Multidisciplinary approach to the treatment of bone metastases: Osteo-Oncology Center, a new organizational model. Tumori\| PubMed ID: 19688966	2009
A phase IB dose-finding trial of liposomal doxorubicin in combination with capecitabine in patients with pretreated metastatic breast cancer. Cancer chemotherapy and pharmacology\| PubMed ID: 19693503	2010
Can we consider zoledronic acid a new antitumor agent? Recent evidence in clinical setting. Current cancer drug targets\| PubMed ID: 20088792	2010
Pathogenesis of osteoblastic bone metastases from prostate cancer. Cancer\| PubMed ID: 20108337	2010
Time-dependent pharmacokinetics of 5-fluorouracil and association with treatment tolerability in the adjuvant setting of colorectal cancer. Journal of clinical pharmacology\| PubMed ID: 21383342	2012
Bone metastases detection by circulating biomarkers: OPG and RANK-L. International journal of oncology\| PubMed ID: 21491082	2011
The role of CXCR4 in the prediction of bone metastases from breast cancer: a pilot study. Oncology\| PubMed ID: 21734413	2011
Role of RANK, RANKL, OPG, and CXCR4 tissue markers in predicting bone metastases in breast cancer patients. Clinical breast cancer\| PubMed ID: 21764390	2011
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature medicine\| PubMed ID: 21822286	2011
Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nature cell biology\| PubMed ID: 23086238	2012
Inhibition of breast cancer cell proliferation in repeated and non-repeated treatment with zoledronic acid. Cancer cell international\| PubMed ID: 23173568	2012
Hormonal receptor, human epidermal growth factor receptor-2, and Ki67 discordance between primary breast cancer and paired metastases: clinical impact. Oncology\| PubMed ID: 23257904	2013
Trastuzumab-induced cardiotoxicity in early breast cancer patients: a retrospective study of possible risk and protective factors. Heart (British Cardiac Society)\| PubMed ID: 23349345	2013
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nature cell biology\| PubMed ID: 23396050	2013
Cisplatin in combination with zoledronic acid: a synergistic effect in triple-negative breast cancer cell lines. International journal of oncology\| PubMed ID: 23403907	2013
Metastatic bone disease in the era of bone-targeted therapy: clinical impact. Tumori\| PubMed ID: 23548992	2013
Efficacy and safety of 12-weekly versus 4-weekly zoledronic acid for prolonged treatment of patients with bone metastases from breast cancer (ZOOM): a phase 3, open-label, randomised, non-in... The Lancet. Oncology\| PubMed ID: 23684411	2013
RANK/RANK-L/OPG in patients with bone metastases treated with anticancer agents and zoledronic acid: a prospective study. International journal of molecular sciences\| PubMed ID: 23702841	2013
What can we learn from the ZOOM trial?--Authors' reply. The Lancet. Oncology\| PubMed ID: 23993381	2013
Bone and cancer: the osteoncology. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases\| PubMed ID: 24133529	2013
Tumor-Induced Osteoclast miRNA Changes as Regulators and Biomarkers of Osteolytic Bone Metastasis. Cancer cell\| PubMed ID: 24135284	2013
A new emergency in oncology: Bone metastases in breast cancer patients (Review). Oncology letters\| PubMed ID: 24137321	2013
Natural history of malignant bone disease in gastric cancer: final results of a multicenter bone metastasis survey. PloS one\| PubMed ID: 24204569	2013
Natural history of malignant bone disease in renal cancer: final results of an Italian bone metastasis survey. PloS one\| PubMed ID: 24386138	2013
Targeting bone metastatic cancer: Role of the mTOR pathway. Biochimica et biophysica acta\| PubMed ID: 24508774	2014
CSF-1 blockade impairs breast cancer osteoclastogenic potential in co-culture systems. Bone\| PubMed ID: 24956020	2014
The microRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasis-suppressive gene prosaposin. The Journal of biological chemistry\| PubMed ID: 24966325	2014
Natural history of malignant bone disease in hepatocellular carcinoma: final results of a multicenter bone metastasis survey. PloS one\| PubMed ID: 25170882	2014
ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling. Nature cell biology\| PubMed ID: 25241036	2014
Single bone metastasis from adenocarcinoma of the lacrimal gland: a case report. Future oncology (London, England)\| PubMed ID: 25303054	2014
Metronomic capecitabine in gastroenteropancreatic neuroendrocrine tumors: a suitable regimen and review of the literature. OncoTargets and therapy\| PubMed ID: 25364262	2014
Pleural effusion in a patient with metastatic gastrointestinal stromal tumor treated with imatinib: case report. Future oncology (London, England)\| PubMed ID: 25525851	2014
Bone metastases in patients with metastatic renal cell carcinoma: are they always associated with poor prognosis? Journal of experimental & clinical cancer research : CR\| PubMed ID: 25651794	2015
Efficacy of endocrine therapy in relation to progesterone receptor and Ki67 expression in advanced breast cancer. Breast cancer research and treatment\| PubMed ID: 26012644	2015
Progesterone receptor status and clinical outcome in breast cancer patients with estrogen receptor-positive locoregional recurrence. Tumori\| PubMed ID: 26045108	2015
Hypocalcaemia in patients with metastatic bone disease treated with denosumab. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 26093811	2015
Feasibility and utility of re-treatment with (177)Lu-DOTATATE in GEP-NENs relapsed after treatment with (90)Y-DOTATOC. European journal of nuclear medicine and molecular imaging\| PubMed ID: 26112388	2015
Treatment of cancer patients in their last month of life: aimless chemotherapy. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer\| PubMed ID: 26391890	2016
Paraneoplastic hypocalcemia-induced heart failure in advanced breast cancer: A case report and literature review. Oncology letters\| PubMed ID: 26622568	2015
First-line chemotherapy in patients with metastatic gastroenteropancreatic neuroendocrine carcinoma. OncoTargets and therapy\| PubMed ID: 26664145	2015
Natural History of Non-Small-Cell Lung Cancer with Bone Metastases. Scientific reports\| PubMed ID: 26690845	2015
Long-lasting activity of trabectedin in refractory uterine leiomyosarcoma: a case report. BMC cancer\| PubMed ID: 26695071	2015
Distribution and correlates of non-high-density lipoprotein cholesterol and triglycerides in Lebanese school children. Journal of clinical lipidology\| PubMed ID: 27055969	2016
Corrigendum: Natural History of Non-Small-Cell Lung Cancer with Bone Metastases. Scientific reports\| PubMed ID: 27079142	2016
Tirofiban-Induced Thrombocytopenia Occurring with Crohn's Disease. Case reports in cardiology\| PubMed ID: 27144035	2016
Characteristics of Incident Testicular Cancer in Lebanon - 1990-2015 Single Institutional Experience. Asian Pacific journal of cancer prevention : APJCP\| PubMed ID: 27221873	2016
Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model. International journal of molecular sciences\| PubMed ID: 27556456	2016
Recombinant granulocyte colony-stimulating factor (rG-CSF) in the management of neutropenia induced by anthracyclines and ifosfamide in patients with soft tissue sarcomas (NEUSAR). Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer\| PubMed ID: 27568305	2017
[Corrigendum] Cisplatin in combination with zoledronic acid: A synergistic effect in triple-negative breast cancer cell lines. International journal of oncology\| PubMed ID: 27573164	2016
RANKL: A promising circulating marker for bone metastasis response. Oncology letters\| PubMed ID: 27698885	2016
Current classification, treatment options, and new perspectives in the management of adipocytic sarcomas. OncoTargets and therapy\| PubMed ID: 27785071	2016
The Effect of Everolimus in an In Vitro Model of Triple Negative Breast Cancer and Osteoclasts. International journal of molecular sciences\| PubMed ID: 27809291	2016
Innovative approaches to establish and characterize primary cultures: an ex vivo 3D system and the zebrafish model. Biology open\| PubMed ID: 27895047	2017
Splicing factor ratio as an index of epithelial-mesenchymal transition and tumor aggressiveness in breast cancer. Oncotarget\| PubMed ID: 27911856	2017
Activity of Eribulin in a Primary Culture of Well-Differentiated/Dedifferentiated Adipocytic Sarcoma. Molecules (Basel, Switzerland)\| PubMed ID: 27918490	2016
The role of 68Ga-DOTA-NOC PET/CT in evaluating neuroendocrine tumors: real-world experience from two large neuroendocrine tumor centers. Nuclear medicine communications\| PubMed ID: 27922538	2017
Outcome Analysis of First-line Somatostatin Analog Treatment in Metastatic Pulmonary Neuroendocrine Tumors and Prognostic Significance of (18)FDG-PET/CT. Clinical lung cancer\| PubMed ID: 27956089	2017
Vitamin D receptor polymorphisms or serum levels as key drivers of breast cancer development? The question of the vitamin D pathway. Oncotarget\| PubMed ID: 28061456	2017
Everolimus in Pancreatic Neuroendocrine Carcinomas G3. Pancreas\| PubMed ID: 28099254	2017
PET/CT Scanner and Bone Marrow Biopsy in Detection of Bone Marrow Involvement in Diffuse Large B-Cell Lymphoma. PloS one\| PubMed ID: 28099514	2017
CORRECTION: Innovative approaches to establish and characterize primary cultures: an ex vivo 3D system and the zebrafish model. Biology open\| PubMed ID: 28202474	2017
Update on the role of trabectedin in the treatment of intractable soft tissue sarcomas. OncoTargets and therapy\| PubMed ID: 28260930	2017
Prognostic impact of the cumulative dose and dose intensity of everolimus in patients with pancreatic neuroendocrine tumors. Cancer medicine\| PubMed ID: 28547856	2017
Tumor-Stroma Crosstalk in Bone Tissue: The Osteoclastogenic Potential of a Breast Cancer Cell Line in a Co-Culture System and the Role of EGFR Inhibition. International journal of molecular sciences\| PubMed ID: 28758931	2017
Epidemiology and Survival Analysis of Gastrointestinal Stromal Tumors in Lebanon: Real-life study from a Hospital tumor registry 2000-2015. The Gulf journal of oncology\| PubMed ID: 28798000	2017
Management and potentialities of primary cancer cultures in preclinical and translational studies. Journal of translational medicine\| PubMed ID: 29116016	2017
Primary leiomyosarcoma of the bone: a case report and a review of the literature. Medicine\| PubMed ID: 29137065	2017
Osteoblastic bone metastases from neuroendocrine tumor (NET) of unknown origin detected by 18fluorocholine PET/CT and its comparison with 68gallium-DOTATOC PET/CT: Case report and review of ... Medicine\| PubMed ID: 29145267	2017
Primary Culture of Undifferentiated Pleomorphic Sarcoma: Molecular Characterization and Response to Anticancer Agents. International journal of molecular sciences\| PubMed ID: 29292724	2017
Myxofibrosarcoma primary cultures: molecular and pharmacological profile. Therapeutic advances in medical oncology\| PubMed ID: 29449896	2017