Gabriella Sozzi

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori

Affiliated withFondazione IRCCS Istituto Nazionale dei Tumori

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 34	2017

Other Publications

Article	Year
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11891319	2002
Molecular changes track recurrence and progression of bronchial precancerous lesions. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 12234694	2002
Involvement of FHIT in lung carcinogenesis prospects for future clinical gene therapy applications. I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]\| PubMed ID: 12415825	2002
p16(INK4A) Hypermethylation detected by fluorescent methylation-specific PCR in plasmas from non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 12473590	2002
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines. Oncogene\| PubMed ID: 12881716	2003
Evidence of neural differentiation in a case of post-therapy primitive neuroectodermal tumor/Ewing sarcoma of bone. The American journal of surgical pathology\| PubMed ID: 12883251	2003
Quantification of free circulating DNA as a diagnostic marker in lung cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 14507943	2003
Detecting lung cancer in plasma with the use of multiple genetic markers. International journal of cancer\| PubMed ID: 14618621	2004
Molecular cytogenetic characterization of proximal-type epithelioid sarcoma. Genes, chromosomes & cancer\| PubMed ID: 15334553	2004
Dose-dependent effect of FHIT-inducible expression in Calu-1 lung cancer cell line. Oncogene\| PubMed ID: 15361849	2004
Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14. Human mutation\| PubMed ID: 15459955	2004
Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma. Molecular cancer\| PubMed ID: 15469606	2004
The apoptotic pathway triggered by the Fhit protein in lung cancer cell lines is not affected by Bcl-2 or Bcl-x(L) overexpression. Oncogene\| PubMed ID: 15489891	2004
Reduced FEZ1/LZTS1 expression and outcome prediction in lung cancer. Cancer research\| PubMed ID: 15735004	2005
Bilateral preaxial polydactyly in a WAGR syndrome patient. American journal of medical genetics. Part A\| PubMed ID: 15742368	2005
Reproducibility of a semiquantitative measurement of circulating DNA in plasma from neoplastic patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15860889	2005
SMARCB1/INI1 tumor suppressor gene is frequently inactivated in epithelioid sarcomas. Cancer research\| PubMed ID: 15899790	2005
Methylation profile in tumor and sputum samples of lung cancer patients detected by spiral computed tomography: a nested case-control study. International journal of cancer\| PubMed ID: 16152615	2006
Detecting cell-free circulating hTERT mRNA in the plasma may identify a subset of nonsmall cell lung cancer patients. Virchows Archiv : an international journal of pathology\| PubMed ID: 16193293	2006
Wilms tumor in monozygous twins: clinical, pathological, cytogenetic and molecular case report. Journal of pediatric hematology/oncology\| PubMed ID: 16217254	2005
Effects of prolonged storage of whole plasma or isolated plasma DNA on the results of circulating DNA quantification assays. Journal of the National Cancer Institute\| PubMed ID: 16368947	2005
Diadenosines as FHIT-ness instructors. Journal of cellular physiology\| PubMed ID: 16547961	2006
Salvage treatment for childhood ependymoma after surgery only: Pitfalls of omitting "at once" adjuvant treatment. International journal of radiation oncology, biology, physics\| PubMed ID: 16863927	2006
Quantitative analysis of plasma DNA in colorectal cancer patients: a novel prognostic tool. Annals of the New York Academy of Sciences\| PubMed ID: 17108210	2006
Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 17114655	2006
Fragile histidine triad expression in oral squamous cell carcinoma and precursor lesions. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17121892	2006
Non-chromosome 11-p syndromes in Wilms tumor patients: Clinical and cytogenetic report of two Down syndrome cases and one Turner syndrome case. American journal of medical genetics. Part A\| PubMed ID: 17163536	2007
Radiation effects on development of HER2-positive breast carcinomas. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17200337	2007
The role of chromosomal alterations in human cancer development. Journal of cellular biochemistry\| PubMed ID: 17722107	2007
Plasma DNA quantification in lung cancer computed tomography screening: five-year results of a prospective study. American journal of respiratory and critical care medicine\| PubMed ID: 18787214	2009
Fragile histidine triad gene inactivation in lung cancer: the European Early Lung Cancer project. American journal of respiratory and critical care medicine\| PubMed ID: 19096006	2009
EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues. The American journal of pathology\| PubMed ID: 19147828	2009
Prolonged remission of disseminated atypical adenomatous hyperplasia under gefitinib. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 19179908	2009
Tumor-initiating cells of HER2-positive carcinoma cell lines express the highest oncoprotein levels and are sensitive to trastuzumab. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19276287	2009
IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions. PloS one\| PubMed ID: 19582164	2009
The EML4-ALK transcript but not the fusion protein can be expressed in reactive and neoplastic lymphoid tissues. Haematologica\| PubMed ID: 19734424	2009
Plasma DNA levels in spiral CT-detected and clinically detected lung cancer patients: a validation analysis. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 19744743	2009
Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19805294	2009
Fluorodeoxyglucose uptake measured by positron emission tomography and standardized uptake value predicts long-term survival of CT screening detected lung cancer in heavy smokers. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 19861905	2009
Elevated levels of the acute-phase serum amyloid are associated with heightened lung cancer risk. Cancer\| PubMed ID: 20087959	2010
Molecular cytogenetic characterization of stem-like cancer cells isolated from established cell lines. Cancer letters\| PubMed ID: 20435407	2010
Prognostic determinants in epithelioid sarcoma. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 20932739	2011
Treatment of chondral defects of the knee with one step matrix-assisted technique enhanced by autologous concentrated bone marrow: in vitro characterisation of mesenchymal stem cells from il... Injury\| PubMed ID: 20934693	2010
MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21300873	2011
MicroRNAs and lung cancer: from markers to targets. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21623159	2011
Inactivation of both FHIT and p53 cooperate in deregulating proliferation-related pathways in lung cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 22425911	2012
Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)\| PubMed ID: 22465911	2012
Progressive lung cancer determined by expression profiling and transcriptional regulation. International journal of oncology\| PubMed ID: 22469662	2012
Patient-derived xenografts of non small cell lung cancer: resurgence of an old model for investigation of modern concepts of tailored therapy and cancer stem cells. Journal of biomedicine & biotechnology\| PubMed ID: 22547927	2012
Role of microRNAs in lung cancer: microRNA signatures in cancer prognosis. Cancer journal (Sudbury, Mass.)\| PubMed ID: 22647364	2012
Multiparametric molecular characterization of pulmonary sarcomatoid carcinoma reveals a nonrandom amplification of anaplastic lymphoma kinase (ALK) gene. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 22705117	2012
Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysis. Neuro-oncology\| PubMed ID: 23076205	2012
Clinical utility of a plasma-based miRNA signature classifier within computed tomography lung cancer screening: a correlative MILD trial study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 24419137	2014
Assessment of circulating microRNAs in plasma of lung cancer patients. Molecules (Basel, Switzerland)\| PubMed ID: 24619302	2014
YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes. Oncotarget\| PubMed ID: 24810989	2014
Ewing sarcoma of the small bowel: a study of seven cases, including one with the uncommonly reported EWSR1-FEV translocation. Histopathology\| PubMed ID: 24898918	2014
Therapeutic use of microRNAs in lung cancer. BioMed research international\| PubMed ID: 25309923	2014
Potential biomarkers for lung cancer screening. Translational lung cancer research\| PubMed ID: 25806293	2014
Recent advances of microRNA-based molecular diagnostics to reduce false-positive lung cancer imaging. Expert review of molecular diagnostics\| PubMed ID: 25924864	2015
Combination Treatment with All-Trans Retinoic Acid Prevents Cisplatin-Induced Enrichment of CD133+ Tumor-Initiating Cells and Reveals Heterogeneity of Cancer Stem Cell Compartment in Lung Ca... Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 26020124	2015
Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis. Cancer research\| PubMed ID: 26141860	2015
Gene Signatures Stratify Computed Tomography Screening Detected Lung Cancer in High-Risk Populations. EBioMedicine\| PubMed ID: 26425689	2015
Circulating microRNA signature as liquid-biopsy to monitor lung cancer in low-dose computed tomography screening. Oncotarget\| PubMed ID: 26451608	2015
Novel method to detect microRNAs using chip-based QuantStudio 3D digital PCR. BMC genomics\| PubMed ID: 26493562	2015
Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells. Molecular oncology\| PubMed ID: 26514616	2016
IL12RB2 Polymorphisms correlate with risk of lung adenocarcinoma. Immunobiology\| PubMed ID: 26547104	2016
Synergistic Activation upon MET and ALK Coamplification Sustains Targeted Therapy in Sarcomatoid Carcinoma, a Deadly Subtype of Lung Cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 26804638	2016
Screening with Low-Dose Computed Tomography Does Not Improve Survival of Small Cell Lung Cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 26845115	2016
Stopping Smoking Reduces Mortality in Low-Dose Computed Tomography Screening Participants. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 26921675	2016
[Lung cancer screening in high-risk subjects: early detection with LDCT and risk stratification using miRNA-based blood test]. Epidemiologia e prevenzione\| PubMed ID: 26951732	2016
Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes. eLife\| PubMed ID: 26987019	2016
Lung cancer screening with low-dose spiral computed tomography: evidence from a pooled analysis of two Italian randomized trials. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)\| PubMed ID: 27222939	2017
Anaplastic lymphoma kinase aberrations correlate with metastatic features in pediatric rhabdomyosarcoma. Oncotarget\| PubMed ID: 27385213	2016
MicroRNA Profile of Lung Tumor Tissues Is Associated with a High Risk Plasma miRNA Signature. Microarrays (Basel, Switzerland)\| PubMed ID: 27600084	2016
CDCP1 is a novel marker of the most aggressive human triple-negative breast cancers. Oncotarget\| PubMed ID: 27626701	2016
Metabolic Evaluation of Non-Small Cell Lung Cancer Patient-Derived Xenograft Models Using 18F-FDG PET: A Potential Tool for Early Therapy Response. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 27765858	2017
Early Effector T Lymphocytes Coexpress Multiple Inhibitory Receptors in Primary Non-Small Cell Lung Cancer. Cancer research\| PubMed ID: 27979840	2017
GENOMIC PROFILING OF PATIENT-DERIVED XENOGRAFTS FOR LUNG CANCER IDENTIFIES B2M INACTIVATION IMPAIRING IMMUNORECOGNITION. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 28003304	2016
LKB1 Expression Correlates with Increased Survival in Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy and Bevacizumab. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 28119362	2017
mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis. International journal of molecular sciences\| PubMed ID: 28124991	2017
Mutational Profile from Targeted NGS Predicts Survival in LDCT Screening-Detected Lung Cancers. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 28302568	2017
Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 28302866	2017
Inflammatory status and lung function predict mortality in lung cancer screening participants. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)\| PubMed ID: 28333763	2017
Detection of microRNAs Using Chip-Based QuantStudio 3D Digital PCR. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28439837	2017
Baseline and postoperative C-reactive protein levels predict mortality in operable lung cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 28472743	2017
Establishment of patient derived xenografts as functional testing of lung cancer aggressiveness. Scientific reports\| PubMed ID: 28751748	2017