Vadim Cherezov

Molecular Biology, The Scripps Research Institute

Affiliated withThe Scripps Research Institute University of Southern California

Research Area

Biography

Vadim Cherezov has not added Biography.
If you are Vadim Cherezov and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 29	2011
Publication title Cited by 20	2016

Other Publications

Article	Year
Molecular organization of cholesterol in polyunsaturated membranes: microdomain formation. Biophysical journal\| PubMed ID: 11751316	2002
Biophysical and transfection studies of the diC(14)-amidine/DNA complex. Biophysical journal\| PubMed ID: 12023234	2002
Controlling membrane cholesterol content. A role for polyunsaturated (docosahexaenoate) phospholipids. Biochemistry\| PubMed ID: 12369842	2002
Too hot to handle? Synchrotron X-ray damage of lipid membranes and mesophases. Journal of synchrotron radiation\| PubMed ID: 12409619	2002
Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase. Biophysical journal\| PubMed ID: 12496106	2002
Interaction of cholesterol with a docosahexaenoic acid-containing phosphatidylethanolamine: trigger for microdomain/raft formation? Biochemistry\| PubMed ID: 14556634	2003
A robotic system for crystallizing membrane and soluble proteins in lipidic mesophases. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 15388926	2004
Rational design of lipid for membrane protein crystallization. Journal of structural biology\| PubMed ID: 15477097	2004
Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation. Chemistry and physics of lipids\| PubMed ID: 15530450	2004
Membrane protein crystallization in lipidic mesophases with tailored bilayers. Structure (London, England : 1993)\| PubMed ID: 15576026	2004
Room to move: crystallizing membrane proteins in swollen lipidic mesophases. Journal of molecular biology\| PubMed ID: 16490208	2006
Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state 2H NMR reveal differences with phosphatidylcholines. Journal of the American Chemical Society\| PubMed ID: 16620109	2006
Controlling the passage of light through metal microchannels by nanocoatings of phospholipids. The journal of physical chemistry. B\| PubMed ID: 17064131	2006
Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 17671365	2007
Membrane protein crystallization in lipidic mesophases. A mechanism study using X-ray microdiffraction. Faraday discussions\| PubMed ID: 17955811	2007
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science (New York, N.Y.)\| PubMed ID: 17962519	2007
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science (New York, N.Y.)\| PubMed ID: 17962520	2007
In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Proteins\| PubMed ID: 18076035	2008
A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. Structure (London, England : 1993)\| PubMed ID: 18547522	2008
Insights into the mode of action of a putative zinc transporter CzrB in Thermus thermophilus. Structure (London, England : 1993)\| PubMed ID: 18786400	2008
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science (New York, N.Y.)\| PubMed ID: 18832607	2008
LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization. Crystal growth & design\| PubMed ID: 19234616	2008
Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. Journal of molecular recognition : JMR\| PubMed ID: 19353579	2009
Crystallizing membrane proteins using lipidic mesophases. Nature protocols\| PubMed ID: 19390528	2009
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam. Journal of the Royal Society, Interface / the Royal Society\| PubMed ID: 19535414	2009
Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases. Analytical chemistry\| PubMed ID: 20025250	2010
LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Biophysical journal\| PubMed ID: 20409473	2010
Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20665265	2010
Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. Journal of the American Chemical Society\| PubMed ID: 20669948	2010
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (New York, N.Y.)\| PubMed ID: 20929726	2010
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (New York, N.Y.)\| PubMed ID: 21097933	2010
Structure of an agonist-bound human A2A adenosine receptor. Science (New York, N.Y.)\| PubMed ID: 21393508	2011
Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases. Crystal growth & design\| PubMed ID: 21660116	2011
Structure of the human histamine H1 receptor complex with doxepin. Nature\| PubMed ID: 21697825	2011
Lipidic cubic phase technologies for membrane protein structural studies. Current opinion in structural biology\| PubMed ID: 21775127	2011
High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment. PloS one\| PubMed ID: 21814577	2011
Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering. Methods (San Diego, Calif.)\| PubMed ID: 21903166	2011
Diversity and modularity of G protein-coupled receptor structures. Trends in pharmacological sciences\| PubMed ID: 22032986	2012
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Methods (San Diego, Calif.)\| PubMed ID: 22041719	2011
Structure of the human κ-opioid receptor in complex with JDTic. Nature\| PubMed ID: 22437504	2012
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature\| PubMed ID: 22596163	2012
Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis. Structure (London, England : 1993)\| PubMed ID: 22658748	2012
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure (London, England : 1993)\| PubMed ID: 22681902	2012
Structural basis for allosteric regulation of GPCRs by sodium ions. Science (New York, N.Y.)\| PubMed ID: 22798613	2012
Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes. The Journal of biological chemistry\| PubMed ID: 23095758	2012
Structure-function of the G protein-coupled receptor superfamily. Annual review of pharmacology and toxicology\| PubMed ID: 23140243	2013
The GPCR Network: a large-scale collaboration to determine human GPCR structure and function. Nature reviews. Drug discovery\| PubMed ID: 23237917	2013
Structural basis for molecular recognition at serotonin receptors. Science (New York, N.Y.)\| PubMed ID: 23519210	2013
Structural features for functional selectivity at serotonin receptors. Science (New York, N.Y.)\| PubMed ID: 23519215	2013
Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 23633594	2013
Structure of the human smoothened receptor bound to an antitumour agent. Nature\| PubMed ID: 23636324	2013
Hydrogen bonding of cholesterol in the lipidic cubic phase. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 23763339	2013
Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline. Journal of synchrotron radiation\| PubMed ID: 23765294	2013
Structure of the human glucagon class B G-protein-coupled receptor. Nature\| PubMed ID: 23863937	2013
Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. Molecular pharmacology\| PubMed ID: 24021214	2013
Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (New York, N.Y.)\| PubMed ID: 24030490	2013
The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor. Structure (London, England : 1993)\| PubMed ID: 24210756	2013
Functional assay for T4 lysozyme-engineered G protein-coupled receptors with an ion channel reporter. Structure (London, England : 1993)\| PubMed ID: 24268646	2014
Serial femtosecond crystallography of G protein-coupled receptors. Science (New York, N.Y.)\| PubMed ID: 24357322	2013
Molecular control of δ-opioid receptor signalling. Nature\| PubMed ID: 24413399	2014
Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nature communications\| PubMed ID: 24525480	2014
Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. Science (New York, N.Y.)\| PubMed ID: 24603153	2014
Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature\| PubMed ID: 24670650	2014
Allosteric sodium in class A GPCR signaling. Trends in biochemical sciences\| PubMed ID: 24767681	2014
Agonist-bound structure of the human P2Y12 receptor. Nature\| PubMed ID: 24784220	2014
Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 24914147	2014
Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nature communications\| PubMed ID: 25008467	2014
Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography. Nature protocols\| PubMed ID: 25122522	2014
Constitutive phospholipid scramblase activity of a G protein-coupled receptor. Nature communications\| PubMed ID: 25296113	2014
Two classes of cholesterol binding sites for the β2AR revealed by thermostability and NMR. Biophysical journal\| PubMed ID: 25418299	2014
Generic GPCR residue numbers - aligning topology maps while minding the gaps. Trends in pharmacological sciences\| PubMed ID: 25541108	2015
Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science (New York, N.Y.)\| PubMed ID: 25612609	2015
Structural basis for bifunctional peptide recognition at human δ-opioid receptor. Nature structural & molecular biology\| PubMed ID: 25686086	2015
GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 25772061	2015
Two disparate ligand-binding sites in the human P2Y1 receptor. Nature\| PubMed ID: 25822790	2015
Lipidic cubic phase serial millisecond crystallography using synchrotron radiation. IUCrJ\| PubMed ID: 25866654	2015
Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. Cell\| PubMed ID: 25913193	2015
Fluorescence Recovery After Photobleaching in Lipidic Cubic Phase (LCP-FRAP): A Precrystallization Assay for Membrane Proteins. Methods in enzymology\| PubMed ID: 25950976	2015
A novel inert crystal delivery medium for serial femtosecond crystallography. IUCrJ\| PubMed ID: 26177184	2015
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature\| PubMed ID: 26200343	2015
Serial femtosecond crystallography of soluble proteins in lipidic cubic phase. IUCrJ\| PubMed ID: 26306196	2015
Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. The Journal of biological chemistry\| PubMed ID: 26420482	2015
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. Structure (London, England : 1993)\| PubMed ID: 26526853	2015
The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR-Ligand Interactions. Journal of chemical information and modeling\| PubMed ID: 26642258	2016
Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nature communications\| PubMed ID: 26673816	2015
Serial femtosecond X-ray diffraction of enveloped virus microcrystals. Structural dynamics (Melville, N.Y.)\| PubMed ID: 26798819	2015
X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Scientific data\| PubMed ID: 27070998	2016
Serial femtosecond crystallography datasets from G protein-coupled receptors. Scientific data\| PubMed ID: 27479354	2016
Serial Femtosecond Crystallography of Membrane Proteins. Advances in experimental medicine and biology\| PubMed ID: 27553241	2016