Sabine Gilch

Dept. of Ecosystem and Public Health, University of Calgary

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 24	2017

Other Publications

Article	Year
Prion-protein-specific aptamer reduces PrPSc formation. Chembiochem : a European journal of chemical biology\| PubMed ID: 12203970	2002
Essential role of the prion protein N terminus in subcellular trafficking and half-life of cellular prion protein. The Journal of biological chemistry\| PubMed ID: 12431994	2003
Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells. The Journal of biological chemistry\| PubMed ID: 12637572	2003
Promising developments bringing prion diseases closer to therapy and prophylaxis. Trends in molecular medicine\| PubMed ID: 13129701	2003
Prion diseases: from molecular biology to intervention strategies. Chembiochem : a European journal of chemical biology\| PubMed ID: 14661267	2003
Recognition of lumenal prion protein aggregates by post-ER quality control mechanisms is mediated by the preoctarepeat region of PrP. Traffic (Copenhagen, Denmark)\| PubMed ID: 15030571	2004
The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells. The Journal of biological chemistry\| PubMed ID: 15247213	2004
The prion protein requires cholesterol for cell surface localization. Molecular and cellular neurosciences\| PubMed ID: 16278084	2006
Prion infection influences murine endogenous retrovirus expression in neuronal cells. Biochemical and biophysical research communications\| PubMed ID: 16564028	2006
Antibodies to a nonconjugated prion protein peptide 95-123 interfere with PrP( Sc ) propagation in prion-infected cells. Cellular and molecular neurobiology\| PubMed ID: 17205391	2007
Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cel... The FEBS journal\| PubMed ID: 17313482	2007
Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation. Veterinary microbiology\| PubMed ID: 17493775	2007
Peptide aptamers expressed in the secretory pathway interfere with cellular PrPSc formation. Journal of molecular biology\| PubMed ID: 17574575	2007
The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery. Journal of neurovirology\| PubMed ID: 17849316	2007
CpG and LPS can interfere negatively with prion clearance in macrophage and microglial cells. The FEBS journal\| PubMed ID: 17944938	2007
Cell type-specific cleavage of nucleocapsid protein by effector caspases during SARS coronavirus infection. Journal of molecular biology\| PubMed ID: 18155731	2008
Neuroendocrine cultured cells counteract persistent prion infection by down-regulation of PrPc. Molecular and cellular neurosciences\| PubMed ID: 18387818	2008
Targeting prion proteins in neurodegenerative disease. Expert opinion on biological therapy\| PubMed ID: 18549323	2008
Toxic effects of intracerebral PrP antibody administration during the course of BSE infection in mice. Prion\| PubMed ID: 19164902	2007
Autophagy induction by trehalose counteracts cellular prion infection. Autophagy\| PubMed ID: 19182537	2009
Therapy in prion diseases: from molecular and cellular biology to therapeutic targets. Infectious disorders drug targets\| PubMed ID: 19200010	2009
Aptamers against prion proteins and prions. Cellular and molecular life sciences : CMLS\| PubMed ID: 19396399	2009
Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells. The Journal of biological chemistry\| PubMed ID: 19748890	2009
Inhibition of cholesterol recycling impairs cellular PrP(Sc) propagation. Cellular and molecular life sciences : CMLS\| PubMed ID: 19823766	2009
Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20615969	2010
Chronic wasting disease. Topics in current chemistry\| PubMed ID: 21598099	2011
Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein. The Journal of biological chemistry\| PubMed ID: 21835918	2011
Severe acute respiratory syndrome coronavirus replication is severely impaired by MG132 due to proteasome-independent inhibition of M-calpain. Journal of virology\| PubMed ID: 22787216	2012
Failure of prion protein oxidative folding guides the formation of toxic transmembrane forms. The Journal of biological chemistry\| PubMed ID: 22955286	2012
A genome-wide survey for prion-regulated miRNAs associated with cholesterol homeostasis. BMC genomics\| PubMed ID: 22985096	2012
Early detection of chronic wasting disease prions in urine of pre-symptomatic deer by real-time quaking-induced conversion assay. Prion\| PubMed ID: 23764839	2013
Assessing proteinase K resistance of fish prion proteins in a scrapie-infected mouse neuroblastoma cell line. Viruses\| PubMed ID: 25402173	2014
Cholesterol balance in prion diseases and Alzheimer's disease. Viruses\| PubMed ID: 25419621	2014
Prion infection impairs lysosomal degradation capacity by interfering with rab7 membrane attachment in neuronal cells. Scientific reports\| PubMed ID: 26865414	2016
Early and Non-Invasive Detection of Chronic Wasting Disease Prions in Elk Feces by Real-Time Quaking Induced Conversion. PloS one\| PubMed ID: 27829062	2016
High prevalence of prion protein genotype associated with resistance to chronic wasting disease in one Alberta woodland caribou population. Prion\| PubMed ID: 28350512	2017
Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency. PLoS pathogens\| PubMed ID: 28800624	2017