Neal A. Deluca

Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine

Affiliated withUniversity of Pittsburgh School of Medicine

Research Area

Biography

Neal A. Deluca has not added Biography.
If you are Neal A. Deluca and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2017

Other Publications

Article	Year
The initiator element in a herpes simplex virus type 1 late-gene promoter enhances activation by ICP4, resulting in abundant late-gene expression. Journal of virology\| PubMed ID: 11799149	2002
Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection. Journal of virology\| PubMed ID: 11836395	2002
Phosphorylation of transcription factor Sp1 during herpes simplex virus type 1 infection. Journal of virology\| PubMed ID: 12050359	2002
Temperature-dependent conformational changes in herpes simplex virus ICP4 that affect transcription activation. Journal of virology\| PubMed ID: 12584349	2003
Relationship of herpes simplex virus genome configuration to productive and persistent infections. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12796511	2003
Treatment of rat gliosarcoma brain tumors by HSV-based multigene therapy combined with radiosurgery. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 14529825	2003
Differential cellular requirements for activation of herpes simplex virus type 1 early (tk) and late (gC) promoters by ICP4. Journal of virology\| PubMed ID: 15163709	2004
Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production. Journal of virology\| PubMed ID: 15280450	2004
Inhibition of DNA repair by a herpes simplex virus vector enhances the radiosensitivity of human glioblastoma cells. Cancer research\| PubMed ID: 15958578	2005
Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector. Virology\| PubMed ID: 16996101	2007
DNA-dependent oligomerization of herpes simplex virus type 1 regulatory protein ICP4. Journal of virology\| PubMed ID: 17581987	2007
Relaxed repression of herpes simplex virus type 1 genomes in Murine trigeminal neurons. Journal of virology\| PubMed ID: 17855552	2007
Binding of ICP4, TATA-binding protein, and RNA polymerase II to herpes simplex virus type 1 immediate-early, early, and late promoters in virus-infected cells. Journal of virology\| PubMed ID: 18094162	2008
Stabilized binding of TBP to the TATA box of herpes simplex virus type 1 early (tk) and late (gC) promoters by TFIIA and ICP4. Journal of virology\| PubMed ID: 18216093	2008
Oligomerization of ICP4 and rearrangement of heat shock proteins may be important for herpes simplex virus type 1 prereplicative site formation. Journal of virology\| PubMed ID: 18434395	2008
Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 18728637	2008
Epigenetic modulation of gene expression from quiescent herpes simplex virus genomes. Journal of virology\| PubMed ID: 19535445	2009
Reversal of heterochromatic silencing of quiescent herpes simplex virus type 1 by ICP0. Journal of virology\| PubMed ID: 21191021	2011
Activities of ICP0 involved in the reversal of silencing of quiescent herpes simplex virus 1. Journal of virology\| PubMed ID: 21411540	2011
Herpes simplex virus 1 ICP4 forms complexes with TFIID and mediator in virus-infected cells. Journal of virology\| PubMed ID: 21450820	2011
The N terminus and C terminus of herpes simplex virus 1 ICP4 cooperate to activate viral gene expression. Journal of virology\| PubMed ID: 22496239	2012
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23027953	2012
Requirement of the N-terminal activation domain of herpes simplex virus ICP4 for viral gene expression. Journal of virology\| PubMed ID: 23135715	2013
Temporal association of herpes simplex virus ICP4 with cellular complexes functioning at multiple steps in PolII transcription. PloS one\| PubMed ID: 24147125	2013
Transcription of the herpes simplex virus 1 genome during productive and quiescent infection of neuronal and nonneuronal cells. Journal of virology\| PubMed ID: 24719411	2014
Selective recruitment of nuclear factors to productively replicating herpes simplex virus genomes. PLoS pathogens\| PubMed ID: 26018390	2015
History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains. Virology\| PubMed ID: 26547038	2016
Production of immunogenic West Nile virus-like particles using a herpes simplex virus 1 recombinant vector. Virology\| PubMed ID: 27336950	2016
Replication-Coupled Recruitment of Viral and Cellular Factors to Herpes Simplex Virus Type 1 Replication Forks for the Maintenance and Expression of Viral Genomes. PLoS pathogens\| PubMed ID: 28095497	2017
A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts. mBio\| PubMed ID: 28611249	2017