Jeung Whan Han

School of Pharmacy, SungKyunKwan University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2017

Other Publications

Article	Year
Cooperation of H2O2-mediated ERK activation with Smad pathway in TGF-beta1 induction of p21WAF1/Cip1. Cellular signalling\| PubMed ID: 15979845	2006
Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells. The Journal of biological chemistry\| PubMed ID: 11698395	2002
Autotaxin promotes motility via G protein-coupled phosphoinositide 3-kinase gamma in human melanoma cells. FEBS letters\| PubMed ID: 11943209	2002
Oligosaccharide-linked acyl carrier protein, a novel transmethylase inhibitor, from porcine liver inhibits cell growth. Archives of pharmacal research\| PubMed ID: 12214857	2002
5-Fluorouracil inhibits nitric oxide production through the inactivation of IkappaB kinase in stomach cancer cells. Biochemical pharmacology\| PubMed ID: 12417257	2002
Constitutive activation of p70S6k in cancer cells. Archives of pharmacal research\| PubMed ID: 12433206	2002
Doxorubicin inhibits the production of nitric oxide by colorectal cancer cells. Archives of pharmacal research\| PubMed ID: 12433207	2002
Cdc42 and Rac1 are necessary for autotaxin-induced tumor cell motility in A2058 melanoma cells. FEBS letters\| PubMed ID: 12482591	2002
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells. Clinical & experimental metastasis\| PubMed ID: 12498389	2002
Purification and characterization of nitric oxide synthase from Staphylococcus aureus. FEMS microbiology letters\| PubMed ID: 12770704	2003
Expression of p21(WAF1/Cip1) through Sp1 sites by histone deacetylase inhibitor apicidin requires PI 3-kinase-PKC epsilon signaling pathway. Oncogene\| PubMed ID: 12955081	2003
Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase. Experimental cell research\| PubMed ID: 14516795	2003
Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials. Biochemical and biophysical research communications\| PubMed ID: 14985106	2004
Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells. European journal of biochemistry\| PubMed ID: 15066181	2004
In-vitro and in-vivo anti-allergic actions of Arecae semen. The Journal of pharmacy and pharmacology\| PubMed ID: 15233873	2004
Activation of RBL-2H3 mast cells is dependent on tyrosine phosphorylation of phospholipase D2 by Fyn and Fgr. Molecular and cellular biology\| PubMed ID: 15282299	2004
Hydrogen peroxide mediates Rac1 activation of S6K1. Experimental cell research\| PubMed ID: 15475011	2004
Inhibitory activity of Chrysanthemi sibirici herba extract on RBL-2H3 mast cells and compound 48/80-induced anaphylaxis. Journal of ethnopharmacology\| PubMed ID: 15507370	2004
Development of a liquid chromatography/electrospray tandem mass spectrometry assay for the quantification of apicidin, a novel histone deacetylase inhibitor, in rat serum: application to a p... Rapid communications in mass spectrometry : RCM\| PubMed ID: 15645510	2005
Effect of a fermented ginseng extract, BST204, on the expression of cyclooxygenase-2 in murine macrophages. International immunopharmacology\| PubMed ID: 15778128	2005
p85 beta-PIX is required for cell motility through phosphorylations of focal adhesion kinase and p38 MAP kinase. Experimental cell research\| PubMed ID: 15893751	2005
beta-Carboline alkaloid suppresses NF-kappaB transcriptional activity through inhibition of IKK signaling pathway. Journal of toxicology and environmental health. Part A\| PubMed ID: 16326420	2005
Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression in RAW 264.7 macrophages by sesquiterpene lactones. Journal of toxicology and environmental health. Part A\| PubMed ID: 16326428	2005
Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells. The Journal of biological chemistry\| PubMed ID: 16326706	2006
Apoptotic potential of sesquiterpene lactone ergolide through the inhibition of NF-kappaB signaling pathway. The Journal of pharmacy and pharmacology\| PubMed ID: 16354403	2005
Histone deacetylase inhibitor apicidin induces cyclin E expression through Sp1 sites. Biochemical and biophysical research communications\| PubMed ID: 16516150	2006
Rubiae Radix suppresses the activation of mast cells through the inhibition of Syk kinase for anti-allergic activity. The Journal of pharmacy and pharmacology\| PubMed ID: 16597368	2006
Immunoglobulin can be functionally regulated by protein carboxylmethylation in Fc region. Archives of pharmacal research\| PubMed ID: 16756083	2006
Phospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cells. Blood\| PubMed ID: 16861349	2006
Involvement of HDAC1 and the PI3K/PKC signaling pathways in NF-kappaB activation by the HDAC inhibitor apicidin. Biochemical and biophysical research communications\| PubMed ID: 16870149	2006
Autotaxin stimulates urokinase-type plasminogen activator expression through phosphoinositide 3-kinase-Akt-nuclear [corrected] factor kappa B signaling cascade in human melanoma cells. Melanoma research\| PubMed ID: 17013094	2006
Activation of hypoxia-inducible factor-1alpha is necessary for lysophosphatidic acid-induced vascular endothelial growth factor expression. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17085645	2006
PKCepsilon is essential for gelsolin expression by histone deacetylase inhibitor apicidin in human cervix cancer cells. Biochemical and biophysical research communications\| PubMed ID: 17257588	2007
Reversal of multidrug resistance by 4-chloro-N-(3-((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)phenyl)benzamide through the reversible inhibition of P-glycoprotein. Biochemical and biophysical research communications\| PubMed ID: 17286965	2007
Coordinated change of a ratio of methylated H3-lysine 4 or acetylated H3 to acetylated H4 and DNA methylation is associated with tissue-specific gene expression in cloned pig. Experimental & molecular medicine\| PubMed ID: 17334232	2007
Meliae cortex extract exhibits anti-allergic activity through the inhibition of Syk kinase in mast cells. Toxicology and applied pharmacology\| PubMed ID: 17395225	2007
Suppression of the NF-kappaB signalling pathway by ergolide, sesquiterpene lactone, in HeLa cells. The Journal of pharmacy and pharmacology\| PubMed ID: 17430640	2007
Reversine stimulates adipocyte differentiation and downregulates Akt and p70(s6k) signaling pathways in 3T3-L1 cells. Biochemical and biophysical research communications\| PubMed ID: 17490611	2007
Modification of cap group in delta-lactam-based histone deacetylase (HDAC) inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 17904843	2007
Histone chaperones regulate histone exchange during transcription. The EMBO journal\| PubMed ID: 17914459	2007
Hypoxia enhances LPA-induced HIF-1alpha and VEGF expression: their inhibition by resveratrol. Cancer letters\| PubMed ID: 17919812	2007
Histone deacetylase inhibitor apicidin-mediated drug resistance: involvement of P-glycoprotein. Biochemical and biophysical research communications\| PubMed ID: 18275843	2008
Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk. The Journal of allergy and clinical immunology\| PubMed ID: 18394691	2008
TIMP-2 disrupts FGF-2-induced downstream signaling pathways. Microvascular research\| PubMed ID: 18721821	2008
Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model. Experimental & molecular medicine\| PubMed ID: 18985016	2008
Reversine increases the plasticity of lineage-committed cells toward neuroectodermal lineage. The Journal of biological chemistry\| PubMed ID: 19015271	2009
Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells. Experimental & molecular medicine\| PubMed ID: 19116446	2008
Rapamycin down-regulates inducible nitric oxide synthase by inducing proteasomal degradation. Biological & pharmaceutical bulletin\| PubMed ID: 19483303	2009
Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells: involvement of Nanog suppression. Cancer research\| PubMed ID: 19567677	2009
Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway. Journal of pharmacological sciences\| PubMed ID: 19763044	2009
A novel gamma-lactam-based histone deacetylase inhibitor potently inhibits the growth of human breast and renal cancer cells. Biological & pharmaceutical bulletin\| PubMed ID: 19801834	2009
The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression. Nucleic acids research\| PubMed ID: 19906718	2010
Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival. Stem cells (Dayton, Ohio)\| PubMed ID: 20049900	2010
HDAC inhibitors downregulate MRP2 expression in multidrug resistant cancer cells: implication for chemosensitization. International journal of oncology\| PubMed ID: 21170509	2011
Myogenic transcriptional activation of MyoD mediated by replication-independent histone deposition. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21173268	2011
Histone chaperones cooperate to mediate Mef2-targeted transcriptional regulation during skeletal myogenesis. Biochemical and biophysical research communications\| PubMed ID: 21414300	2011
Requirement of protein l-isoaspartyl O-methyltransferase for transcriptional activation of trefoil factor 1 (TFF1) gene by estrogen receptor alpha. Biochemical and biophysical research communications\| PubMed ID: 22382029	2012
The role of histone chaperones in osteoblastic differentiation of C2C12 myoblasts. Biochemical and biophysical research communications\| PubMed ID: 22705305	2012
Protein L-isoaspartyl methyltransferase regulates p53 activity. Nature communications\| PubMed ID: 22735455	2012
PRMT6 overexpression upregulates TSP-1 and downregulates MMPs: its implication in motility and invasion. Biochemical and biophysical research communications\| PubMed ID: 23380452	2013
Dissecting the roles of the histone chaperones reveals the evolutionary conserved mechanism of transcription-coupled deposition of H3.3. Nucleic acids research\| PubMed ID: 23563152	2013
DNA microarray profiling of genes differentially regulated by three heterochromatin protein 1 (HP1) homologs in Drosophila. Biochemical and biophysical research communications\| PubMed ID: 23611785	2013
Destabilization of TNF-α mRNA by Rapamycin. Biomolecules & therapeutics\| PubMed ID: 24116273	2012
Reversine induces multipotency of lineage-committed cells through epigenetic silencing of miR-133a. Biochemical and biophysical research communications\| PubMed ID: 24513286	2014
The role of tumor suppressor menin in IL-6 regulation in mouse islet tumor cells. Biochemical and biophysical research communications\| PubMed ID: 25088994	2014
HP1β suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2. International journal of oncology\| PubMed ID: 25201136	2014
Epigenetic activation of the Foxa2 gene is required for maintaining the potential of neural precursor cells to differentiate into dopaminergic neurons after expansion. Stem cells and development\| PubMed ID: 25233056	2015
Identification of small molecules that inhibit the histone chaperone Asf1 and its chromatin function. BMB reports\| PubMed ID: 26058396	2015
Syntaxin 4 regulates the surface localization of a promyogenic receptor Cdo thereby promoting myogenic differentiation. Skeletal muscle\| PubMed ID: 26347807	2015
JQ1, an inhibitor of the epigenetic reader BRD4, suppresses the bidirectional MYC-AP4 axis via multiple mechanisms. Oncology reports\| PubMed ID: 26573731	2016
Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer. Oncotarget\| PubMed ID: 27081696	2016
S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis. Molecular cell\| PubMed ID: 27151441	2016
Patent cliff and strategic switch: exploring strategic design possibilities in the pharmaceutical industry. SpringerPlus\| PubMed ID: 27347468	2016
Epigenetic role of nuclear S6K1 in early adipogenesis. BMB reports\| PubMed ID: 27439608	2016
Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Experimental & molecular medicine\| PubMed ID: 27515126	2016
Mapping the Technological Knowledge Landscape: The Case of Epigenetics. Recent patents on anti-cancer drug discovery\| PubMed ID: 27557814	2016
PKN2 and Cdo interact to activate AKT and promote myoblast differentiation. Cell death & disease\| PubMed ID: 27763641	2016
A new manufacturing process to remove thrombogenic factors (II, VII, IX, X, and XI) from intravenous immunoglobulin gamma preparations. Biologicals : journal of the International Association of Biological Standardization\| PubMed ID: 27876270	2017
Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 28432138	2017